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Effect of cumulative exposure to tacrolimus on the recurrence of hepatocellular carcinoma after liver transplantation

Kim DG, Lee JG, Joo DJ, Kim MS

Background: Previous studies reported that maintaining at lower trough level of tacrolimus could reduce the recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT); however, this has never been assessed...
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Antiplatelet drugs on the recurrence of hepatocellular carcinoma after liver transplantation

Kim DG, Choi MC, Min EK, Lee JG, Joo DJ, Kim MS

Background: Previous studies reported suppressive effects of antiplatelet agents on hepatocellular carcinoma (HCC); however, this has never been assessed in patients who underwent liver transplantation (LT). Methods: This retrospective observational study...
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Cancer prevalence and risk factors among Korean solid organ transplant recipients

Min J, Choi N, Kim J, Hong KT, Ahn YH, Kim MS, Kang HG

Background: With the number of solid organ transplantations (SOT) in Korea increasing, interest in long-term complications in solid organ transplant recipients (SOTRs) is also increasing. Malignancy is one of the...
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Current trends and clinical impact of cytomegalovirus prophylaxis in kidney transplant recipients in Korea: the Korean Organ Transplantation Registry study

Kim JS, Lee NR, Kim MS, Yang J, Park KI, Hwang HS, Ko MJ, Jeong KH

Background: Cytomegalovirus (CMV) infection is a frequent and devastating complication after kidney transplantation (KT). To minimize adverse effects of CMV, anti-viral prophylaxis is considered an essential treatment in KT recipients,...
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Incident fractures in kidney transplant recipients: a nationwide cohort study from South Korea

Eum SH, Lee JH, Jeon JS, Jun H, Yang J, Kim MS, Yoon HE

Background: An increased fracture incidence is a challenging issue in kidney transplant recipients (KTRs). This study investigated the incidence, location, and predictors of fractures after kidney transplantation (KT). Methods: Data were...
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Clinical impact of early blood transfusion after kidney transplantation

Kang MY, Lee J, Kang MY, Min E, Yim SH, Choi M, Kim HJ, Huh KH, Kim MS

Background: Pretransplant blood transfusion is well-known cause of allosensitization. However, the effects of blood transfu-sion after kidney transplantation on graft outcomes remain controversial. Methods: We analyzed 785 patients who underwent human...
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Clinical significance of late onset antibody-mediated rejection without donor-specific anti-human leukocyte antigen antibodies in kidney transplantation

Lee J, Lim BJ, Kim BS, Kim MS, Huh KH

Background: Late onset antibody-mediated rejection (AMR) is a leading cause of allograft failure after kidney transplantation. Although the presence of donor-specific antibodies (DSA) is no longer required for AMR diagnosis...
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Initial high anti-ABO isoagglutinin titer is a major red flag of bacterial infection in ABO-incompatible living donor liver transplantation

Choi MC, Min EK, Yim SH, Kim DG, Lee JG, Joo DJ, Kim MS

Background: Many previous studies showed comparable clinical outcomes of ABO-incompatible (ABOi) living donor liver trans-plantation (LDLT) compared to ABO-compatible (ABOc) LDLT, but there were few studies related to initial high...
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The unusual grafts for living donor liver transplantation

Yim SH, Min EK, Choi MC, Kim DG, Lee JG, Han DH, Joo DJ, Choi GH, Kim MS

Background: To find an adequate graft for living donor liver transplantation (LDLT), the left lobe and the right lobe grafts of the liver were introduced. However, the left lobe graft...
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Impact of low-level donor-specific anti-HLA antibody on posttransplant clinical outcomes of kidney transplant recipients: analysis from Korean Organ Transplantation Registry data

Lee H, Park JH, Park JW, Ban TH, Yang J, Kim MS, Yang CW, Chung BH, Korean Organ Transplantation Registry

Background: The clinical relevance of donor-specific anti-human leukocyte antigen antibody (HLA-DSA), detected only by solid phase assay (SPA) remains controversial. This study aimed to investigate the impact of low-level donor-specific...
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Association of pretransplant skeletal muscle mass with outcomes in kidney transplant recipients

Kim HJ, Hong N, Kim HW, Yang J, Kim BS, Huh KH, Kim MS, Lee J

Background: Muscle wasting in chronic kidney disease is associated with increased cardiovascular events, morbidity, and mortality. However, whether pretransplantation skeletal muscle mass affects kidney transplantation outcomes has not been established. Methods:...
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Clinical association between tacrolimus intra-patient variability and liver transplantation outcomes in patients with and without hepatocellular carcinoma

Kim HJ, Lee JG, Joo DJ, Kim MS, Lee J

Tacrolimus is the mainstay of immunosuppression in liver transplantation to prevent rejection. However, the clinical use of tacrolimus is complicated by its narrow therapeutic window and significant intra-patient variability (IPV)....
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Comparison of humoral immunogenicity in solid organ transplant recipients after third-dose mRNA vaccine with homologous or heterologous schedules: an observational study

Kang J, Lee J, Huh KH, Joo DJ, Lee JG, Jung I, Kim S, Park Y, Kim MS

Background: Solid organ transplant recipients (SOTRs) are susceptible to severe coronavirus disease 2019 (COVID-19) and im-munogenicity studies of Omicron variants according to vaccination schedules are lacking. We examined the humoral...
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Humoral immunogenicity of two doses of BNT162b2 in pediatric solid organ transplant recipients

Baek JY, Ihn K, Koh H, Lee KH, Kim MY, Kim S, Kang JM, Choi JY, Park Y, Kim MS

Background: Pediatric solid organ transplant recipients (SOTRs) are at high risk of severe COVID-19, but studies on their COVID-19 vaccine immunogenicity are lacking. We investigated the humoral immunogenicity of pediatric...
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Transition of metabolic dysfunction after kidney transplantation and its association with transplant outcomes: a nationwide prospective cohort study

Lee YH, Song SH, Song SH, Shin HS, Yang J, Kim MS, Hwang HS

Background: Kidney transplantation is expected to modify the metabolic status. However, it remains unclear whether the transition of metabolic status before and after transplantation affects the transplant outcomes. Methods: We analyzed...
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Immune Responses to Plant-Derived Recombinant Colorectal Cancer Glycoprotein EpCAM-FcK Fusion Protein in Mice

Lim CY, Kim DS, Kang Y, Lee YR, Kim K, Kim DS, Kim MS, Ko K

Epidermal cell adhesion molecule (EpCAM) is a tumor-associated antigen (TAA), which has been considered as a cancer vaccine candidate. The EpCAM protein fused to the fragment crystallizable region of immunoglobulin...
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Antitumor Effect of Low-Dose of Rapamycin in a Transgenic Mouse Model of Liver Cancer

Lee HS, Kim JY, Ro SW, Kim MS, Kim H, Joo DJ

Purpose: We investigate whether low-dose rapamycin is effective in preventing hepatocellular carcinoma (HCC) growth and treating HCC after tumor development in transgenic mice. Materials and Methods: We established transgenic mice with...
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Comparison of amikacin with fosfomycin as an add-on to ciprofloxacin for antibiotic prophylaxis in transrectal prostate biopsy: A single-center retrospective study

Yu SH, Jung SI, Ryu JW, Kim MS, Chung HS, Hwang EC, Kwon DD

Purpose: To assess the effect of ciprofloxacin (CP) and fosfomycin compared with CP and amikacin in patients with a fluoroquinolone (FQ)-resistant rectal flora who have undergone transrectal ultrasound-guided prostate biopsy...
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Postherpetic Trigeminal Trophic Syndrome: A Case Report

Lee JH, Uh JA, Kim JH, Kim HY, Kim MS, Lee UH, Lee SK

Trigeminal trophic syndrome (TTS) is a rare condition characterized by anesthesia, paresthesia, and facial ulceration involving the trigeminal dermatome secondary to self-manipulation of the skin after a peripheral or central...
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Livedo reticularis following administration of ChAdOx1 nCoV-19 vaccine (AZD1222): a report of two cases

Kim JH, Uh JA, Kim HS, Lee SK, Kim MS, Lee UH

The cutaneous appearance of transient or persistent livedo reticularis is characterized by violaceous, mottled, ring-shaped interconnecting lesions that form a reticular or net-like pattern. It can occur physiologically in response...
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