Korean J Pediatr Hematol Oncol.
2000 Apr;7(1):129-135.
A Case of the Idiopathic Hypereosinophilic Syndrome Evolving to Malignant Lymphoma
- Affiliations
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- 1Department of Pediatrics, Pusan National University College of Medicine, Pusan, Korea. limyt@hyowon.pusan.ac.kr
Abstract
- Idiopathic hypereosinophilic syndrome refers to the clinical disorder characterized by persistent eosinophilia and systemic signs of involvement in which specific causative factors for eosinophilia cannot be verified during a certain period. It is primarily a disease of the adult man, but is found very rarely in infancy and childhood. There have been only a few reported cases of this syndrome in association with acute lymphoblastic leukemia but an overt lymphoma has not been described yet. Until now the exact mechanism for malignant transformation of the hypereosinophilic syndrome is not clear. Here the authors experienced a case of idiopathic hypereosinophilic syndrome which evolved to malignant lymphoma in a 17-month-old boy.
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