Korean J Pathol.  1999 Aug;33(8):624-626.

Chronic Hepatitis in the Idiopathic Hypereosinophilic Syndrome: A case report

• Kim KH
• Sul HJ
• Jun SC
• Kang DY

Abstract

Chronic hepatitis associated with the idiopathic hypereosinophilic syndrome has been very rarely reported worldwide. Recently, we experienced a case of chronic hepatitis with piecemeal necrosis as the clinical feature of the idiopathic hypereosinophilic syndrome. The patient was a 49-year-old woman who complained of a mild fever, nausea, vomiting, and pain in the right upper quadrant. The eosinophil count of peripheral blood increased up to 14,020/microliter (64% of WBC). Liver biopsy specimen showed severe porto-periportal inflammation with marked eosinophilic infiltration and ballooning degeneration of hepatocytes. Corticosteroid therapy significantly normalized the eosinophil count of peripheral blood.

Keyword

Idiopathic hypereosinophilic syndrome; Chronic hepatitis

MeSH Terms

Biopsy
Eosinophils
Female
Fever
Hepatitis, Chronic*
Hepatocytes
Humans
Hypereosinophilic Syndrome*
Inflammation
Liver
Middle Aged
Nausea
Necrosis
Vomiting