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Clinical Applications of the Microbiome in Obstetrics

Pyeon SY, Kang DY, Kim SY, Choi SW, Hwang MY, Lee YJ

Human microbiome refers to the genetic material of approximately 1013 microorganisms present in the human body. These microbiomes interact significantly with the physiological, metabolic, and immune systems, particularly during pregnancy....
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Analysis of Fluoroquinolone Adverse Drug Reaction Reported in a Single Center

Kim HJ, Hwang S, Kim HH, Jang JY, Suh JH, Kang DY, Lee JY, Kang HR

Objective: With the increased use of fluoroquinolone in the clinical setting, adverse drug reactions (ADR) to fluoroquinolones are also on the rise. The purpose of this study was to analyze...
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Risk Factors for Clostridium difficile Infection in Antibiotic Use Inpatients Based on Common Data Model

Moon SH, Kim HH, Nam DH, Moon Y, Kang MG, Choi IY, Byeon Sj, Yang HJ, Kim SH, Kim K, Kang DY

Objective: Clostridium difficile infection (CDI) is affected by various factors. The association between CDI and antibiotic use is well known, and proton pump inhibitors (PPI) and histamine H2 receptor antagonist...
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Sodium-Glucose Cotransporter-2 Inhibitor-Related Diabetic Ketoacidosis: Accuracy Verification of Operational Definition

Kang DY, Kim H, Ko S, Kim H, Shinn J, Kang MG, Byeon Sj, Choi JH, Shin SY, Kim HS

Background: The most important aspect of a retrospective cohort study is the operational definition (OP) of the disease. We developed a detailed OP for the detection of sodiumglucose cotransporter-2 inhibitors...
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Functional Angioplasty: Definitions, Historical Overview, and Future Perspectives

Park H, Kang DY, Lee CW

Percutaneous coronary intervention (PCI) is used to treat obstructive coronary artery disease (CAD). The role of PCI is well defined in acute coronary syndrome, but that for stable CAD remains...
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The clinical and microbiological effects of non-surgical periodontal treatments in necrotizing periodontal disease: case report

Kim S, Lee J, Kang DY, Shin HS

Necrotizing periodontal disease caused by plaque bacteria is showed clinical findings including pseudo-membrane, interproximal necrosis of the affected area, pain on palpation and gingiva bleeding. Microbiological examination is showed that...
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A Retrospective Study on the Factors Affecting the Early Marginal Bone Loss of Tissue-Level Implants

Koo SM, Kang DY, Hieu PD, Shin HS, Park JC

Purpose: Marginal bone loss (MBL) around dental implants adversely affects long-term implant treatment outcomes. The purpose of this study was to investigate the risk factors of MBL in tissuelevel implants. Materials...
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Adverse Drug Reactions to First-line Anti-tubercular Drugs Based on Individual Case Safety Report in a Single Tertiary Hospital

Kim HH, Moon M, Choi N, Kang DY, Chae KO, Lee J, Lim JJ, Cho SH, Kang HR

Background/Aims: Tuberculosis has incidence and mortality rates that are among the highest for all communicable diseases. Adverse drug reactions (ADRs) to anti-tubercular drugs are common, and have a major impact...
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Surveillance of Adverse Drug Reactions to First-line Antitu berculosis Drugs Using Common Data Model

Byeon Sj, Park HA, Kang DY, Choi IY, Choi JH

Objective: Tuberculosis (TB) remains a major health problem with high rates of mortality in Korea. Adverse drug reactions (ADRs) to anti-TB drugs negatively affect drug compliance, lead to poor prognosis,...
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Drug Labeling Status of Culprit Drugs Inducing Severe Cutaneous Adverse Reactions

Yeom HJ, Kim HHw, Kim HJ, Park S, Jang JY, Park GY, Kang DY, Kang HR

Objective: The labeling status of culprit drugs of Severe Cutaneous Adverse Reactions (SCAR) was evaluated by comparing the labeling status of the US Food and Drug Administration (FDA) to the...
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Adverse Reactions after the Second Dose of ChAdOx1 COVID-19 Vaccine in H ealthcare Workers

Kim HJ, Kim HH, Park S, Yeom HJ, Jang JY, Park Gy, Kang HR, Kang DY

Objective: The Seoul National University Hospital Drug Safety Monitoring Center performed a prospective survey regarding adverse reactions after the second dose of the adenovirus-vectored vaccine (ChAdOx1 nCoV-19) in healthcare workers....
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3D analysis of soft tissue around implant after flap folding suture

Jung SY, Kang DY, Shin HS, Park JC

Purpose: The various suture techniques can be utilized in order to maximize the keratinized tissue healing around dental implants. The aim of this study is to compare the soft tissue...
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A 10-Year Single-Center Experience of Adverse Drug Reaction Monitoring

Park SB, Moon M, Kim HH, Park GY, Kang DY, Lee JY, Cho YS, Kang HR, Cho SH

Background/Aims: Despite proper use of pharmaceuticals, adverse drug reactions (ADRs) can lead to problems related to patient safety. We analyzed the characteristics of ADRs, particularly serious adverse events (SAEs), in...
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Transpyloric optic navigation of tumor using a laparoscope during totally laparoscopic distal gastrectomy for gastric cancer

Lee S, Kim HG, Kang DY, Kim DY, Ryu SY

Purpose: The purpose of this study was to describe the technique of intraoperative transpyloric optic navigation (TPON) and determine its efficacy and feasibility during totally laparoscopic distal gastrectomy (TLDG) in...
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Precautions for COVID-19 Vaccination

Kim HJ, Kim HH, Park GY, Kang DY

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Improving the Prescription System to Prevent Adverse Drug Reactions

Kim HJ, Moon M, Kim HH, Park S, Kang RY, Park GY, Kang HR, Kang DY

Objective: Many medical institutions provide warnings when physicians prescribe medication with a history of adverse reaction to prevent adverse drug reaction. If the range of warning is too narrow, it...
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Characteristics of Adverse Drug Reactions of Central Muscle Relaxants Including Eperisone: Analysis of KAERS Data

Park G, Sohn JE, Moon M, Lee JY, Kang HR, Kang DY

  • KMID: 2534638
  • J Pharmacoepidemiol Risk Manage.
  • 2020 Sep;12(2):79-84.
Objective: Eperisone is the most widely prescribed muscle relaxant in Korea. However, few studies have investigated the adverse drug reactions (ADRs) of eperisone in the Korean population. A study is...
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Application of Deep Learning in Dentistry and Implantology

Kang DY, Duong HP, Park JC

Artificial intelligence and deep learning algorithms are infiltrating various fields of medicine and dentistry. The purpose of the current study was to review literatures applying deep learning algorithms to the...
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Comparison of one-bag and multibag desensitization protocols for the prevention of rituximab hypersensitivity

Kim HH, Moon M, Cho MK, Ahn KM, Chung S, Kang DY, Lee SY, Cho SH, Kang HR

Purpose: Rituximab is prone to infusion-related reactions, which commonly requires desensitization to maintain its administration. Conventional desensitization protocols are using multistep infusion by diluting solutions. However, the process of diluting...
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Sinus of Valsalva Thrombosis Detected on Computed Tomography after Transcatheter Aortic Valve Replacement

Lim SJ, Koo HJ, Jung SC, Kang DY, Ahn JM, Park DW, Park SJ, Yang DH, Kang JW

Background and Objectives: Leaflet thrombosis after transcatheter aortic valve replacement (TAVR) has been reported recently, whereas thrombus formation in sinus of Valsalva has yet to be fully evaluated. This study...
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