Korean J Anesthesiol.  1994 Dec;27(12):1734-1739. 10.4097/kjae.1994.27.12.1734.

A Comparison of The Induction Characteristics of Propofol and Thiopental on The Hypertensive Patients

• Kwon BY
• Lee JS
• Kim SH

• KMID: 2240456
• DOI: http://doi.org/10.4097/kjae.1994.27.12.1734

Abstract

We have compared the cardiovascular effects during intravenous induction and endotracheal intubation with propofol or thiopental sodium on the forty hypertensive patients. Propofol was given 2 mg/kg or thiopental sodium was given 5 mg/kg intravenously for induction of general anesthesia, and endotracheal intubation. The patients were allocated in two groups according to the intravenous anesthetic sgents that were administered (Group I; 20 patients Propofol group and Group II; 20 patients Thiopental group), Arterial blood pressure and heart rate was recorded by automatic noninvasive blood pressure cuff (ESCORT 100/200 Medical Data Electronics. Arleta Ca. U.S.A.). Systolic, diastolic arterial blood pressure, and heart rates were recorded 1 minute before administration of intravenous anesthetic agents, 1 minute and 5 minutes after endotracheal intubation. Reduction of systolic and diastolic arterial blood pressure were significantly greater after propofol(30%) than thiopental sodium administration and intubation. The change of the heart rate after propofol induction and intubation was not significant. However, the heart rate was increased about 23% after thiopental sodium induction and intubation. The results of this study indicate that propofol 2 mg/kg intravenous induction and intubation for hypertensive surgical patient should be contribute to patients prognosis.

Keyword

Anesthesia; Intravenouis propofol; Thiopental sadium

MeSH Terms

Anesthesia
Anesthesia, General
Anesthetics
Arterial Pressure
Blood Pressure
Heart Rate
Humans
Intubation
Intubation, Intratracheal
Prognosis
Propofol*
Thiopental*
Anesthetics
Propofol
Thiopental