Korean J Anesthesiol.  2004 Aug;47(2):292-295. 10.4097/kjae.2004.47.2.292.

Hyperamylasemia Due to Ruptured Cerebral Aneurysm: A case report

• Kim JB
• Jung HJ
• Chung DS
• Im KS
• Park K

• KMID: 2237547
• DOI: http://doi.org/10.4097/kjae.2004.47.2.292

Abstract

Unexpected findings of hyperamylasemia have been observed in patients with primary neurosurgical abnormalities without abdominal trauma or evidence of pancreatitis. However, the causes of hyperamylasemia in abovementioned cases have not been clearly elucidated. We have experienced hyperamylasemia in a 66 year-old female patient with subarachnoid hemorrhage caused by ruptured cerebral aneurysms who had had 2 aneurysms in right pericallosal and left middle cerebral trifurcational artery. Among the 2 aneurysms, the one in right pericallosal artery was ruptured and subarachnoid, intraventricular and intracranial hemorrhage was observed on the initial brain CT scan. There was no specific problem during operation and patient's staying in recovery room. Seven hours after the operation finished, severe hypotension and metabolic acidosis were occurred. Vital signs and acidosis were corrected with fluid and bicarbonate therapy. We incidentally found marked hyperamylasemia in the first postoperative day and serum amylase level was decreased and thereafter normalized through the seventh postoperative day. There was no evidence of acute pancreatitis on either clinical examination or radiologic study of abdominal sonography and CT scan. On the brain CT scan which was taken on the third postoperative day, the increase in the amount of hemorrhage in bilateral frontal area was found and cerebral ischemia was observed in the territory of bilateral anterior cerebral artery.

Keyword

amylase; brain; cerebral aneurysm; subarachnoid hemorrhage

MeSH Terms

Acidosis
Aged
Amylases
Aneurysm
Anterior Cerebral Artery
Arteries
Brain
Brain Ischemia
Female
Hemorrhage
Humans
Hyperamylasemia*
Hypotension
Intracranial Aneurysm*
Intracranial Hemorrhages
Pancreatitis
Recovery Room
Subarachnoid Hemorrhage
Tomography, X-Ray Computed
Vital Signs
Amylases