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Knockdown of CPEB1 and CPEB4 Inhibits Scar Formation via Modulation of TAK1 and SMAD Signaling

Cui HS, Lee YR, Ro YM, Joo SY, Cho YS, Kim JB, Kim DH, Seo CH

Background: Cytoplasmic polyadenylation element binding (CPEB) proteins are sequencespecific RNA-binding proteins that control translation via cytoplasmic polyadenylation. We previously reported that CPEB1 or CPEB4 knockdown suppresses TAK1 and SMAD signaling...
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Is It Safe to Preserve Left Atrial Appendage During Maze Procedure?

Song K, Jang WS, Park N, Kim YS, Kim JB

Background and Objectives: The left atrial appendage (LAA) can contribute significantly to LA mechanical contraction. Nevertheless, the preventive effect of LAA occlusion during the maze procedure against cerebral infarction remains...
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Functional Insufficiency of Mitral and Tricuspid Valves Associated With Atrial Fibrillation: Impact of Postoperative Atrial Fibrillation Recurrence on Surgical Outcomes

Kim K, Kim HJ, Jung SH, Lee J, Kim JB

Background and Objectives: To identify the factors associated with adverse outcomes following surgery for functional insufficiency of the mitral valve (MV) or tricuspid valve (TV) associated with atrial fibrillation (AF). Methods:...
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Prognosis of Unrepaired Ascending Aorta after the Surgical Replacement of Bicuspid Aortic Valves

Shin HJ, Kim WK, Kim DK, Kim HJ, Kim JB

Background: The surgical threshold for bicuspid aortic valve (BAV)-related aortopathy is a matter of debate due to its uncertain etiology and prognosis. This study investigated the prognosis of unrepaired BAV...
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Development and validation of equation for cardiorespiratory fitness in patients with heart failure with preserved ejection fraction

Battumur B, Lee JE, Park SH, Choi YJ, Kang DO, Park EJ, Kim JB, Choi JY, Roh SY, Na JO, Choi CU, Kim JW, Rha SW, Park CG, Kim EJ

Background/Aims: Cardiorespiratory fitness (CRF), as measured by maximal oxygen consumption (VO2max), is an important independent predictive factor of cardiovascular outcomes in patients with heart failure (HF). However, it is unclear...
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Safety of low-dose anticoagulation in extracorporeal membrane oxygenation using the Permanent Life Support System: a retrospective observational study

Song K, Kim JB

Background: Bleeding and thrombosis are major complications associated with high mortality in extracorporeal membrane oxygenation (ECMO) management. Anticoagulant therapy should be adequate to reduce thrombosis. However, related studies are limited. Methods:...
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The Effect of a Computerized Pharmacist Communication Application-based SBAR Tool

Cheon YJ, Ye KN, Kim JB, Kim JT, An SH

Background: Pharmacists communicate with a variety of healthcare experts to prevent medication errors. Situation-BackgroundAssessment-Recommendation (SBAR) is a tool used for concise and...
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The Profile of Early Sedation Depth and Clinical Outcomes of Mechanically Ventilated Patients in Korea

Hyun Dg, Ahn JH, Gil HY, Nam CM, Yun C, Lee JM, Kim JH, Lee DH, Kim KH, Kim DJ, Lee SM, Ryu HG, Hong SK, Kim JB, Choi EY, Baek J, Kim J, Kim EJ, Park TY, Kim JH, Park S, Park CM, Jung WJ, Choi NJ, Jang HJ, Lee SH, Lee YS, Suh GY, Choi WS, Lee KS, Kim HW, Min YG, Lee SJ, Lim CM

Background Current international guidelines recommend against deep sedation as it is associated with worse outcomes in the intensive care unit (ICU). However, in Korea the prevalence of deep sedation and its...
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Evaluation of fracture strength and translucency of 3D printing resin crown for carious primary anterior tooth

Ham YJ, Lee JH, Kim JS, Kim JB, Han MR, Shin JS

Objectives: The purpose of this study was to compare the fracture strength and traslucency of 3D printing resin crowns according to different thicknesses. Methods: Resin crowns were designed with CAD software...
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Growth inhibition by fusidic acid in cervical, thyroid, and breast carcinoma cell lines

Kim JY, Jegal BS, Koh AR, Park KS, Kim JB, Bae J

ObjectiveWe investigated the effects of fusidic acid (FA) on human cervical, thyroid, and breast carcinoma cell lines to determine the potential usefulness of FA in cancer treatment. MethodsSix cancer cell lines...
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The Change of Suicidal Ideation Over a 12-Week Naturalistic Treatment of Depression: Comparison Between Young People and Older Adults

Jung YE, Jun TY, Woo YS, Yim HW, Kim JB, Kim JM, Seo HJ

Objective We investigated the differences in suicidality between young people and older adults with depression over the course of 12-week naturalistic treatment with antidepressants. Methods A total of 565 patients who...
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Oral Anticoagulation Therapy in Atrial Fibrillation Patients with Advanced Chronic Kidney Disease: CODE-AF Registry

Park H, Yu HT, Kim TH, Park J, Park JK, Kang KW, Shim J, Kim JB, Kim J, Choi EK, Park HW, Lee YS, Joung B

Purpose: Advanced chronic kidney disease (CKD), including end-stage renal disease (ESRD) on dialysis, increases thromboembolic risk among patients with atrial fibrillation (AF). This study examined the comparative safety and efficacy...
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Simultaneous heart-kidney transplantation during mechanical circulatory support in a patient with bilateral iliac artery stenosis

Lee S, Song KS, Kim YS, Jang WS, Kim JB, Park NH, Park WY, Park UJ, Kim H, Kim IC

A 54-year-old male patient was admitted to the emergency room due to cardiac arrest. He had history of coronary artery bypass surgery 3 years ago. Despite the surgery and optimal...
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Postoperative outcomes and risk factors for cardiac surgery in solid organ transplant recipients

Kim K, Jung SH, Yoo JS, Kim HJ, Kim JB, Choo SJ, Chung CH, Lee JW

Background: This study aimed to investigate postoperative outcomes and risk factors associated with mortality and readmission after cardiac surgery in solid organ transplant recipients. Methods: We retrospectively analyzed 78 adult solid...
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Trends in Heart Valve Surgery in Korea: A Report from the Heart Valve Surgery Registry Database

Choi JW, Kim JB, Jung YJ, Hwang HY, Kim KH, Yoo JS, Lee S, Lee SH, Sung K, Je HG, Lim MH, Chang BC, Hong SC, Lee H, Shin YC, Kim JH, Lim C

Background: In this study, we present recent trends in heart valve surgery in Korea through analyses of data from the Korea Heart Valve Surgery Registry (KHVSR). Methods: We enrolled 8,981 patients...
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Validation of Biomarker-Based ABCD Score in Atrial Fibrillation Patients with a Non-Gender CHA2DS2 -VASc Score 0–1: A Korean Multi-Center Cohort

Jung M, Byeon K, Kang KW, Park YM, Hwang YM, Lee SH, Jin ES, Roh SY, Kim JS, Ahn J, Lee SR, Choi EK, Ahn Ms, Lee EM, Park HC, Lee KH, Kim M, Choi JH, Ko JS, Kim JB, Kim C, Lip GY, Shin SY, Clinical Survey on Stroke Prevention in Patients with Atrial Fibrillation (CS-SPAF) Investigators

Purpose: Atrial fibrillation (AF) patients with low to intermediate risk, defined as non-gender CHA2DS2-VASc score of 0–1, are still at risk of stroke. This study verified the usefulness of ABCD...
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Association of Gender With Clinical Outcomes in a Contemporary Cohort of Patients With Atrial Fibrillation Receiving Oral Anticoagulants

Kim M, Kim J, Kim JB, Park J, Park JK, Kang KW, Shim J, Choi EK, Lee YS, Park HW, Joung B

Background and Objectives: In patients with atrial fibrillation (AF), females taking vitamin K antagonist are at higher risk of stroke or systemic embolism (SSE), bleeding and all-cause death than males....
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Reduction in malodor, gingival index and plaque index after 4-week use of new concept oral irrigator

Kim HJ, Kim JB

Objectives: This study aimed to evaluate the changes in clinical indexes related to periodontitis, such as malodor, gingival and plaque indexes, during the adjuvant use of a high pressure oral...
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Inhibitory Effects of Copper, Brass, and Stainless Steel Surfaces on Multidrug-Resistant Microorganisms

Kim JB, Kim JK, Lee J, Chae HS, Lee HK, Park Y

Background: The aim of this study was to analyze the inhibitory effects of copper, brass (78% copper, 22% tin), and stainless steel surfaces on multidrug-resistant Acinetobacter baumannii (MRAB), extended-spectrum beta-lactamase...
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Garcinia Cambogia-Induced Refractory Status Epilepticus

Nam Hw, Kim KT, Song M, Kim H, Kim JB

Garcinia cambogia (G.cambogia) is a herbal dietary supplement for managing obesity. Several adverse effects of G.cambogia have been reported including serotonin syndrome and mania. We report a patient with refractory...
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