Korean J Clin Pathol.  1999 Apr;19(2):177-180.

A case of Waldenstr's Macroglobulinemia with Pleural Involvement

Affiliations
  • 1Department of Clinical Pathology, College of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea.
  • 2Department of Internal Medicine, College of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea.

Abstract

Waldenstr's macroglobulinemia is a slowly progressing disease characterized by proliferation of small lymphocytes, plasmacytoid lymphocytes and plasma cells in the bone marrow with increased serum monoclonal IgM. Since 1944, only a few cases of Waldenstr's macroglobulinemia with pulmonary involvement have been described. We experienced a case of Waldenstr's macroglobulinemia with pulmonary involvement. The patient was 66-year-old male complaining dyspnea. His cytological finding of pleural fluid aspirates revealed many plasmacytoid lymphocytes. Serum electrophoresis showed the sharp M-peak in the gamma globulin region, which was identified as a IgM, kappa type by immunofixation. Bone marrow findings showed small lymphocytic and plasmacytoid lymphocytic infiltration.

Keyword

Waldenstr's macroglobulinemia; Plasmacytoid lymphocytes; Pulmonary involvement

MeSH Terms

Aged
Bone Marrow
Dyspnea
Electrophoresis
gamma-Globulins
Humans
Immunoglobulin M
Lymphocytes
Male
Plasma Cells
Waldenstrom Macroglobulinemia*
Immunoglobulin M
gamma-Globulins
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