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Cost-Effectiveness of Age-Expanding Strategy of Latent Tuberculosis Infection Treatment in Household Contacts in South Korea

Cho H, Seok J, Park Y, Kim HJ, Lee EH, Park J, Park DA, Kang YA, Lee J

Purpose: The strategy of latent tuberculosis infection (LTBI) treatment in household tuberculosis (TB) contacts has been expanding in South Korea. However, there is little evidence of the cost-effectiveness of LTBI...
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Efficient Generation of Dopaminergic Neurons from Mouse Ventral Midbrain Astrocytes

Han JY, Lee EH, Kim SM, Park CH

Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by tremors, bradykinesia, and rigidity. PD is caused by loss of dopaminergic (DA) neurons in the midbrain substantia nigra (SN) and...
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The Efficacy and Safety of a Human Perirenal Adipose TissueDerived Stromal Vascular Fraction in an Interstitial Cystitis Rat Model

Ha JY, Lee EH, Chun SY, Lee JN, Ha YS, Chung JW, Yoon BH, Jeon M, Kim HT, Kwon TG, Yoo ES, Kim BS

BACKGROUND: Interstitial cystitis (IC) is a chronic and intractable disease that can severely deteriorate patients’ quality of life. Recently, stem cell therapy has been introduced as a promising alternative treatment...
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A Nationwide Survey on Gastrointestinal Endoscopy Practice Patterns among Pediatric Endoscopists in South Korea

Lee YM, Lee Y, Choi SY, Kim HJ, Hong SJ, Kang Y, Lee EH, Lee KJ, Choi Y, Yi DY, Kim S, Kang B

Purpose: Gastrointestinal (GI) endoscopy is an important tool for diagnosing and treating GI diseases in children. This study aimed to analyze the current GI endoscopy practice patterns among South Korean...
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Reduced Cytotoxicity by Repetitive mRNA Transfection in Differentiated Neurons

Ko SH, Kang JS, Kim SM, Lee EH, Park CH

Background and Objectives: mRNA-based protein expression technology has been used to express functional proteins. We have previously generated dopamine neurons from rat-embryo derived neural precursor cells (NPCs) through repeated transfection...
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Implementation and Validation of an Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantifying Levetiracetam and Lamotrigine in Serum Specimens

Yi A, Lee JH, Nam HG, Han J, Cho SE, Lee SG, Lee EH

We validated an ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for quantifying levetiracetam (LEV) and lamotrigine (LAM) in serum specimens. We developed an UHPLCMS/MS method using Triple Quad 4500MD...
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Cardiac Complications Associated with Eating Disorders in Children: A Multicenter Retrospective Study

Choi SY, Lee KJ, Kim SC, Lee EH, Lee YM, Kim YB, Yi DY, Kim JY, Kang B, Jang HJ, Hong SJ, Choi YJ, Kim HJ

Purpose: Eating disorders often result in somatic complications, including cardiac abnormalities. Cardiac abnormalities may involve any part of the heart, including the cardiac conduction system, and can lead to sudden...
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Factors Associated with Cyto-Histological Misinterpretation of Cervical Smear according to Menopausal Status

Choi MS, Lee YJ, Lee EH, Ji YI, Park MJ

Objectives: This study aimed to compare histological outcomes between pre-menopausal and post-menopausal women with cervical cytological abnormalities and to investigate the clinical factors affecting the misinterpretation of cytology and histology. Methods:...
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A Case of Smooth Muscle Actin-Positive Cutaneous Spindle Cell Squamous Cell Carcinoma

Sohng C, Lee EH, Park KD, Jang YH, Lee WJ, Lee SJ, Kim JY

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Improving the Performance of Radiologists Using Artificial Intelligence-Based Detection Support Software for Mammography: A Multi-Reader Study

Lee JH, Kim KH, Lee EH, Ahn JS, Ryu JK, Park YM, Shin GW, Kim YJ, Choi HY

Objective: To evaluate whether artificial intelligence (AI) for detecting breast cancer on mammography can improve the performance and time efficiency of radiologists reading mammograms. Materials and Methods: A commercial deep learning-based...
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Effects of Black Ginseng Water Extract under the Inflammatory Conditions of Cultured Sebocytes and Outer Root Sheath Cells

Kim JY, Kwack MH, Lee EH, Lee WJ

Background: Ginseng has been used in Korea for a long time as a restorative herbal medicine. Black ginseng (BG) is made from red or white ginseng by multiple steamy and...
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Pathophysiological Role of TLR4 in Chronic Relapsing Itch Induced by Subcutaneous Capsaicin Injection in Neonatal Rats

Kim HJ, Lee EH, Lim YH, Jeong D, Na HS, Jung Y

Despite the high prevalence of chronic dermatitis and the accompanied intractable itch, therapeutics that specifically target itching have low efficacy. Increasing evidence suggests that TLRs contribute to immune activation and...
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The Mediating Effects of Health Concern and Depression in the Relation between Self-quarantined People’s COVID-19 Stress and Fatigue

Shin SH, Lee EH

Purpose: This study was to investigate the mediating effects of health concern and depression on the stress and fatigue of COVID-19 self-quarantine. Methods: This was a cross-sectional study. A total...
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Potential Utility of Fecal Calprotectin in Discriminating Colorectal Polyps From Other Major Etiologies in Children Presenting With Isolated Hematochezia

Kim YB, Kim JY, Choi S, Kim HJ, Lee YM, Lee Y, Jang HJ, Lee EH, Lee KJ, Kim SC, Choi SY, Kang Y, Yi DY, Choi YJ, Choe BH, Kang B

Background: Colorectal polyps are the most common cause of isolated hematochezia in children, which requires a colonoscopy for diagnosis. We aimed to investigate the potential utility of fecal calprotectin (FC)...
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Surveillance of Close Contacts and Implications of Pediatric Patients with COVID-19–Experiences from a Single Residential Treatment Center

Baek YJ, Chung WS, Lee KH, Lee EH, Lee SJ, Kim J, Kim JH, Ahn JY, Jeong SJ, Choi JY, Yeom JS

Residential treatment centers (RTCs) are successful in isolating and closely monitoring adults confirmed with coronavirus disease 2019 (COVID-19), but there are concerns for children who need care. This study was...
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Defining the Relationship between Daily Exposure to Particulate Matter and Hospital Visits by Psoriasis Patients

Lee EH, Ryu D, Hong NS, Kim JY, Park KD, Lee WJ, Lee SJ, Kim SH, Do Y, Jang YH

Background: Although particulate matter likely provokes inflammatory reactions in those with chronic skin disorders like atopic dermatitis, no study has examined the relationship between particulate matter and psoriasis exacerbation. Objective: This...
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Dermatofibrosarcoma Protuberans with Diversely Atypical Clinical Presentation: Three Case Reports

Lee SH, Lee EH, Han MH, Lee SJ

  • KMID: 2525572
  • Korean J Dermatol.
  • 2022 Jan;60(1):53-56.
Dermatofibrosarcoma protuberans (DFSP) is a relatively rare, slow-growing dermal spindle cell tumor characterized by high local recurrence rates and a low risk of metastasis. It starts as an erythematous indurated...
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Implementation and Validation of a Gas Chromatography-Mass Spectrometry Method for Pristanic Acid and Phytanic Acid Quantification in Plasma Specimens

Yi A, Lee JH, Yoo G, Lim HJ, Park E, Han J, Kim GY, Cho SE, Lee SG, Lee EH

We validated a gas chromatography-mass spectrometry (GC-MS) method for quantifying pristanic acid (PrA) and phytanic acid (PhA) in plasma specimens. We developed a GC-MS method based on the analysis of 20...
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Fulminant Course of Acute Necrotizing Encephalopathy Followed by Serial MRI: A Case Report

Lee JY, Lee KM, Yeon EK, Lee EH, Kim EJ

Acute necrotizing encephalopathy (ANE) is a rare but distinctive type of influenza-associated encephalopathy characterized by symmetric multiple lesions with an invariable thalamic involvement. Although the exact pathogenesis of ANE remains...
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Analysis of the virtual simulation practice and high fidelity simulation practice training experience of nursing students: A mixed-methods study

Lee EH, Ryu SY

Purpose: This study used an exploratory sequential approach (mixed methods) design to explore essential meaning through comparing and analyzing the experiences of nursing students in virtual simulation practice and high...
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