Korean J Gastroenterol.  1999 Apr;33(4):568-573.

A Case of Waldenstrm's Macroglobulinemia with Portal Hypertension

• Kim JH
• Kwan SW
• Choi JS
• Bae SH
• Lee DJ
• Lee HJ

Abstract

Macroglobulinemia was first described by Waldenstr m' s in 1944. It is charaterized by heavy accu mulation of monoclonal IgM in the plasma and infilration of plasmacytoid lymphocyte in bone mar row, lymph node, liver, and spleen. Its clinical manifestations include fatigue, weight loss, bleeding diathesis, hepatomegaly, lyphadenophathy, occular changes and neurologic symptom. Hyperviscosity syndrome may develop as a complication of macroglobulinemia. We have experienced one case o Waldenstr m' s macroglobulinemia with portal hypertension.

Keyword

Waldenstr m' s macroglobulinemia; Portal hypertension; Hyperviscosity syndrome

MeSH Terms

Disease Susceptibility
Fatigue
Hemorrhage
Hepatomegaly
Hypertension, Portal*
Immunoglobulin M
Liver
Lymph Nodes
Lymphocytes
Neurologic Manifestations
Plasma
Spleen
Waldenstrom Macroglobulinemia*
Weight Loss
Immunoglobulin M