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Lenalidomide for anemia correction in lower-risk del(5q) myelodysplastic syndrome patients of Asian ethnicity

Hong J, Lee YJ, Bae SH, Yi JH, Park S, Chang MH, Park YH, Hyun SY, Chung JS, Jang JE, Jung JY, Jeon SY, Song SY, Kim H, Kim DS, Kim SH, Kim MK, Han SH, Park S, Kim YJ, Lee JH, on behalf of the AML/MDS Working Party of the Korean Society of Hematology

Background To estimate real-world outcomes in East Asian populations, we conducted a nationwide retrospective analysis of the efficacy and safety of lenalidomide for del(5q) myelodysplastic syndrome (MDS) patients with transfusion-dependent anemia...
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The Relationship between Nursing Care Needs and Nurse Staffing in Pulmonology Nursing Units

Jo HK, Bae SH

Purpose: This study aimed to examine the relationship between nursing care needs and nurse staffing in pulmonology units. Methods: This was a descriptive study that used a retrospective design. In...
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Transvaginal Direct Puncture and Ethanol Sclerotherapy for Cervicovaginal Venous Malformations: A Case Report and Literature Review

Jeong GS, Bae SH, Do YS, Lee HN, Lee SJ

Cervicovaginal venous malformations are extremely rare. Sclerotherapy is proven to be effective for superficial venous malformations but not for venous malformations in the lower genital tract of female. A 52-year-old...
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Relationship between Hearing Loss and Dementia Differs According to the Underlying Mechanism

Jung J, Bae SH, Han JH, Kwak SH, Nam GS, Lee PH, Sohn YH, Yun M, Ye BS

Background and Purpose The associations between hearing loss (HL) and the mechanisms underlying cognitive impairment (CI) remain unclear. We evaluated the effects of clinical factors, vascular magnetic resonance imaging (MRI)...
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Incidence of Postnatal CMV Infection among Breastfed Preterm Infants: a Systematic Review and Meta-analysis

Park HW, Cho MH, Bae SH, Lee R, Kim KS

Background: We performed a systematic review and meta-analysis to evaluate the incidence of breast milk-acquired cytomegalovirus (CMV) infection in preterm infants born to CMVseropositive mothers. Methods: PubMed, Embase, and Cochrane Library...
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Updated recommendations for the treatment of venous thromboembolism

Hong J, Ahn SY, Lee YJ, Lee JH, Han JW, Kim KH, Yhim HY, Nam SH, Kim HJ, Song J, Kim SH, Bang SM, Kim JS, Mun YC, Bae SH, Kim HK, Jang S, Park R, Choi HS, Kim I, Oh D, obotKSoHTaHWP

Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, is a condition characterized by abnormal blood clot formation in the pulmonary arteries and the deep venous vasculature. It...
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The 2020 revision of the guidelines for the management of myeloproliferative neoplasms

Kim SY, Bae SH, Bang SM, Eom KS, Hong J, Jang S, Jung CW, Kim HJ, Kim HY, Kim MK, Kim SJ, Mun YC, Nam SH, Park J, Won JH, Choi CW

In 2016, the World Health Organization revised the diagnostic criteria for myeloproliferative neoplasms (MPNs) based on the discovery of disease-driving genetic aberrations and extensive analysis of the clinical characteristics of...
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Interplay between Saturated Free Fatty Acids and mmLDL Induces Inflammation in LPS-stimulated Macrophages

Park JS, Bae SH

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Predicting human pharmacokinetics from preclinical data: absorption

Yim DS, Choi S, Bae SH

Predicting the rate and extent of oral absorption of drugs in humans has been a challenging task for new drug researchers. This tutorial reviews in vivo and PBPK methods reported...
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Clinical Characteristics of Allergy to a Brinzolamide 1.0%/Brimonidine 0.2% Fixed Combination in Korean Glaucoma Patients

Park IK, Bae SH, Kim KW, Chun YS

Purpose: We describe the clinical aspects of allergy to a brinzolamide 1.0%/brimonidine 0.2% fixed combination (BBFC) in Korean patients with glaucoma. Methods: The medical records of 117 glaucoma patients treated with...
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All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells

Kim Y, Jeung HK, Cheong JW, Song J, Bae SH, Lee JI, Min YH

Purpose: Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by...
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Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response

Woo HY, Park JY, Bae SH, Kim CW, Jang JY, Tak WY, Kim DJ, Kim IH, Heo J, Ahn SH

Background/Aims: Suboptimal responses to lamivudine or telbivudine plus adefovir (LAM/LdT+ADV) rescue therapy are common in patients with LAM-resistant hepatitis B virus (HBV) infections. We compared patients switched to entecavir plus...
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Validity and Reliability of the Korean Version of the Menopause-Specific Quality of Life

Park JH, Bae SH, Jung YM

Purpose: This study aimed to evaluate the validity and reliability of the Korean version of Menopause-Specific Quality of Life (MENQOL). Methods: The MENQOL was translated into Korean according to algorithm of...
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Bioimpedance Analysis for Predicting Outcomes of Complex Decongestive Therapy for Gynecological Cancer Related Lymphedema: A Feasibility Study

Bae SH, Kim WJ, Seo YJ, Kim J, Jeon JY

Objective To determine whether the bioimpedance analysis (BIA) ratios of upper to lower extremities could predict treatment outcomes after complex decongestive therapy (CDT) for gynecological cancer related lymphedema (GCRL). Methods A...
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Case Report of Anomalous Head Posture Correction with Low Vision Aid Using Virtual Reality

Kang JW, Bae SH, Yeo JH, Moon NJ

Purpose: To report the successful rehabilitation of a patient with anomalous head posture by using a virtual reality low vision aid (VRLVA). Case summary: A 75-year-old male diagnosed with age-related macular...
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Recurrent late seroma after immediate breast reconstruction with latissimus dorsi musculocutaneous flap

Bae SH, Lee YW, Nam SB, Lee SJ, Park H, Kang T

The latissimus dorsi musculocutaneous flap (LDMCF) is widely used for breast reconstruction. However, it has the disadvantage of frequent seroma formation at the donor site, and late seroma has also...
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Successful Sequential Therapy Involving Regorafenib after Failure of Sorafenib in a Patient with Recurrent Hepatocellular Carcinoma after Liver Transplantation

Lee SK, Jang JW, Nam H, Sung PS, Bae SH, Choi JY, Yoon SK

The efficacy and safety of sequential systemic therapy for the treatment of recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) are not well established. This study describes a successful experience...
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A Case of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis Treated by Hepatic Arterial Infusion Chemotherapy and Radiotherapy

Lee JY, Yoo JJ, Chun SJ, Bae SH, Lee JM, Kim SG, Kim YS

Sorafenib is the standard treatment for advanced hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT). Additionally, hepatic arterial infusion chemotherapy has been used as a treatment option for advanced HCC....
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Image-guided navigation surgery for bilateral choanal atresia with a Tessier number 3 facial cleft in an adult

Sung JY, Cho KS, Bae YC, Bae SH

The coexistence of craniofacial cleft and bilateral choanal atresia has only been reported in three cases in the literature, and only one of those cases involved a Tessier number 3...
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Clinical Perceptions and Practice Patterns for Amblyopia in Korea

Kang JW, Bae SH, Moon NJ

PURPOSE: We used a questionnaire to explore perceptions and clinical practice patterns of Korean pediatric ophthalmologists in terms of amblyopia. METHODS: From September to November 2018, we conducted a web-based questionnaire...
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