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Associations Between Circulating Interleukin-17 Levels and Systemic Lupus Erythematosus and Between Interleukin-17 Gene Polymorphisms and Disease Susceptibility: A Meta-analysis

Lee YH, Song GG

OBJECTIVE: To systematically investigate the relationship between circulating interleukin-17 (IL-17) levels and systemic lupus erythematosus (SLE) and associations between polymorphisms in IL17 genes and SLE susceptibility. METHODS: We performed a meta-analysis...
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Sunburn Deteriorated to a Deep Second-Degree Wound in a Healthy Young Female without Risk Factors

Yoon HS, Na YC

Sunburn is the transient inflammatory response of skin caused by excessive exposure to ultraviolet radiation (UVR). The rate of disease progression varies because each individual has different levels of sunburn...
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Long-term Prognosis of Patients Who Contraindicated for Intravenous Thrombolysis in Acute Ischemic Stroke

Lee BY, Oh JS, Yoon SM

BACKGROUND: As intravenous thrombolysis (IVT) has very restricted inclusion criteria, eligible patients of IVT constitute a very small proportion and studies about their mortality are rare. The long-term mortality in...
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Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Lee JH, Jo KW, Shim TS

BACKGROUND: The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results...
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Omic Approach in Non-smoker Female with Lung Squamous Cell Carcinoma Pinpoints to Germline Susceptibility and Personalized Medicine

Baldassarri M, Fallerini , Cetta F, Ghisalberti M, Bellan C, Furini S, Spiga O, Crispino S, Gotti G, Ariani F, Paladini P, Renieri A, Frullanti

PURPOSE: Lung cancer is strongly associated to tobacco smoking. However, global statistics estimate that in females the proportion of lung cancer cases that is unrelated to tobacco smoking reaches fifty...
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Diabetes-Related Cardiac Dysfunction

Williams L, Nye BG, Wende AR

The proposal that diabetes plays a role in the development of heart failure is supported by the increased risk associated with this disease, even after correcting for all other known...
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Evaluation of Antibodies Against Haemophilus influenzae Type b in Korean Adults

Lee JH, Kim HW, Lee S, Kim KH

PURPOSE: After the introduction of Haemophilus influenzae type b (Hib) vaccine in 1995 in Korea, it was included in the national immunization program in 2013. In the post-Hib vaccine era,...
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Gender Difference in Mediating Effects of Self-Efficacy for the Prevention of Sexually Transmitted Diseases (STD) among College Students' STD Knowledge, Susceptibility, and Sexual Autonomy

Park M

PURPOSE: The purpose of the study was to examine the impact of self-efficacy in the prevention of sexually transmitted diseases (STD), knowledge of and susceptibility to STD, and the role...
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Smoking and Hand Dermatitis in the United States Adult Population

Lai YC, Yew YW

BACKGROUND: Hand dermatitis is a common chronic relapsing skin disease resulting from a variety of causes, including endogenous predisposition and environmental exposures to irritants and allergens. Lifestyle factors such as...
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Factors Influencing Intention to Receive Examination of Diabetes Complications

Hsieh YL, Lee FH, Chen CL, Chang MF, Han PH

PURPOSE: The purpose of this study was to understand the situation of diabetes patients receiving examinations for diabetes complications and to explore the factors influencing their intention to receive examinations...
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Genetic Association for P2X7R rs3751142 and CARD8 rs2043211 Polymorphisms for Susceptibility of Gout in Korean Men: Multi-Center Study

Lee SW, Lee SS, Oh DH, Park DJ, Kim HS, Choi JR, Chae SC, Yun KJ, Chung WT, Choe JY, Kim SK

The aim of this study was to determine the association between P2X7R rs3751142 and CARD8 rs2043211 polymorphisms and gout susceptibility in male Korean subjects. This study enrolled a total of...
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Bipolar Disorder: Role of Inflammation and the Development of Disease Biomarkers

Muneer A

Bipolar disorder is a severe and enduring psychiatric condition which in many cases starts during early adulthood and follows a relapsing and remitting course throughout life. In many patients the...
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The Neurobiology of Bipolar Disorder: An Integrated Approach

Muneer A

Bipolar disorder is a heterogeneous condition with myriad clinical manifestations and many comorbidities leading to severe disabilities in the biopsychosocial realm. The objective of this review article was to underline...
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Establishment and evaluation of a murine alphavbeta3-integrin-expressing cell line with increased susceptibility to Foot-and-mouth disease virus

Zhang W, Lian K, Yang F, Yang Y, Zhu Z, Zhu Z, Cao W, Mao R, Jin Y, He J, Guo J, Liu X, Zheng H

Integrin alphavbeta3 plays a major role in various signaling pathways, cell apoptosis, and tumor angiogenesis. To examine the functions and roles of alphavbeta3 integrin, a stable CHO-677 cell line expressing...
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Effects of particulate matter in ambient air on the development and control of asthma

Kim SH, Yang HJ, Jang AS, Kim SH, Song WJ, Kim TB, Ye YM, Yoo Y, Yu J, Yoon JS, Jee HM, Suh DI, Kim CW

There has been growing concern regarding the effects of ambient air pollution on asthma. Particulate matter (PM) is one of the major air pollutants affecting both general population and the...
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Analysis of Predisposing Factors for Hearing Loss in Adults

Lee JS, Choi HG, Jang JH, Sim S, Hong SK, Lee HJ, Park B, Kim HJ

We aimed to estimate the effects of various risk factors on hearing level in Korean adults, using data from the Korea National Health and Nutrition Examination Survey. We examined data...
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Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics

Kim EA, Kim YH, Kang HW, Yoon HY, Kim WT, Kim YJ, Yun SJ, Moon SK, Choi YH, Kim IY, Lee SC, Kim WJ

Mps one binder (MOB) proteins are integral components of signaling pathways that control important cellular processes, such as mitotic exit, centrosome duplication, apoptosis, and cell proliferation. However, the biochemical and...
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Gephyrin: a central GABAergic synapse organizer

Choii G, Ko J

Gephyrin is a central element that anchors, clusters and stabilizes glycine and gamma-aminobutyric acid type A receptors at inhibitory synapses of the mammalian brain. It self-assembles into a hexagonal lattice...
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Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases

Choi UY, Kang JS, Hwang YS, Kim YJ

The study of antiviral pathways to reveal methods for the effective response and clearance of virus is closely related to understanding interferon (IFN) signaling and its downstream target genes, IFN-stimulated...
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Sudden cardiovascular collapse after platelet transfusion during liver transplantation: flat-line thromboelastometry and inferred pulmonary thromboembolism: A case report

Huh IY, Kim SK, Kim HJ, Chung HJ, Hwang GS

Despite the well-known bleeding diathesis in patients with end-stage liver disease, inappropriate hypercoagulation is also emerging as a major concern. Pulmonary thromboembolism (PTE) is a major cause of perioperative morbidity...
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