J Korean Pediatr Soc.  2002 Dec;45(12):1596-1600.

MR Imaging of Disseminated Tuberculosis of the Brain in a Patient with Miliary Tuberculosis: Initial Findings and Changes Six Months after Antituberculous Therapy

• Jang JH
• Lim JW
• Jung SL
• Choeh K
• Han T

Abstract

A 23-month-old girl visited with chronic cough and her chest radiograph showed miliary tuberculosis. There was no neurological abnormality. But CSF findings showed WBC 22/mm3(lymphocyte 20%, neutrophil 80%) and positive result of polymease chain reaction(PCR) for M. tuberculosis. MR imaging showed multiple ring enhanced nodules and ovoid nonenhancing bright signal lesion on the cerebrum, cerebellar parenchyme, and left basal ganglia. Antituberculous chemotherapy was done and follow-up MR imaging was done after six months. One month after treatment, the number and size of nodules had decreased. Six months after treatment, the multiple enhanced nodules and leptomeningeal enhancement were not observed, and high signal intensity of genu portion of left internal capsule and posterior portion of putamen were decreased.

Keyword

Tuberculous meningitis; MR imaging

MeSH Terms

Basal Ganglia
Brain*
Cerebrum
Cough
Drug Therapy
Female
Follow-Up Studies
Humans
Infant
Internal Capsule
Magnetic Resonance Imaging*
Neutrophils
Putamen
Radiography, Thoracic
Tuberculosis*
Tuberculosis, Meningeal
Tuberculosis, Miliary*