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Effectiveness of Intravenous Isoniazid and Ethambutol Administration in Patients with Tuberculosis Meningoencephalitis and HIV Infection

Butov D, Feshchenko Y, Kuzhko M, Gumenuik M, Yurko K, Grygorova , Tkachenko , Nekrasova , Tlustova T, Kikinchuk , Peshenko A, Butova T

BACKGROUND: The aim of this study was to investigate the effectiveness of intravenous isoniazid (H) and ethambutol (E) administered in patients with new sputum positive drug-susceptible pulmonary tuberculosis (TB) with...
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Validation of the Uniform Case Definition Criteria for Differentiating Tuberculous Meningitis, Viral Meningitis, and Bacterial Meningitis in Adults

Kim MC, Park KH, Lee SA, Kim SH

We validated the uniform case definition for differentiating tuberculous meningitis (TBM) from both viral meningitis (VM) and bacterial meningitis (BM) in adults from South Korea, a country with an intermediate...
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Rupture of a Middle Meningeal Artery Pseudoaneurysm in Moyamoya Syndrome Related with Tuberculous Meningitis

Mun HY, Nam TK, Choi HH, Park YS

We report a rare case of a patient with Moyamoya syndrome who presented with intracerebral hemorrhage resulting from rupture of a middle meningeal artery pseudoaneurysm. This 38-year-old woman was unconscious...
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Toxoplasma Encephalitis in a Patient with Human Immunodeficiency Virus Infection

Choi PK, Chung JY, Kang HG

Toxoplasma encephalitis is an opportunistic infection that may occur in immunocompromised or advanced HIV (Human Immunodeficiency Virus) patients and lead to serious complications in the CNS. We report a 44-year-old...
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A New Scoring System for the Differential Diagnosis between Tuberculous Meningitis and Viral Meningitis

Lee SA, Kim SW, Chang HH, Jung H, Kim Y, Hwang S, Kim S, Park HK, Lee JM

BACKGROUND: Tuberculous meningitis (TBM) is associated with high mortality and morbidity despite administering anti-tuberculous chemotherapy to the patients. Differential diagnosis between TBM and viral meningitis (VM) is difficult in some...
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Clinical Feasibility of Suppression Head Impulse Test in Vestibulopathy Patients

Kang YJ, Jun BC, Cho YS, Lim JH, Kim DY

BACKGROUND AND OBJECTIVES: The suppression head impulse (SHIMP) test has emerged as one of the new vestibular function tests. The SHIMP test is an analysis of anti-compensatory saccadic movements in...
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Corticosteroid Treatment for Central Nervous System Infections

Shin DH

Infectious diseases of the central nervous system (CNS) cause inflammatory processes within the brain and spinal cord that can lead to morbidity and mortality in a high proportion of patients....
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Successful Isolation and Treatment of Cogenital Tuberculosis Infection Occurred in Premature Infants in the Neonatal Intensive Care Unit

Yoo S, Chun SH, Lee J, Sung TJ

Congenital tuberculosis is a very rare disease and the affected infants are often delivered prematurely. Even though proper treatment, the mortality rate is high. The preterm male infant born at...
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Tuberculous Meningitis-Mimicking Varicella-Zoster Meningitis

Hong SI, Kim T, Jung J, Park SY, Chong YP, Lee SO, Choi SH, Kim YS, Woo JH, Lee SA, Kim SH

BACKGROUND: Varicella-zoster virus (VZV) is one of the most common etiologies of aseptic meningitis. The severest manifestation of VZV meningitis is occasionally confused with tuberculous meningitis (TBM). Thus, we investigated...
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Surgical Management of Syringomyelia Associated with Spinal Adhesive Arachnoiditis, a Late Complication of Tuberculous Meningitis: A Case Report

Lee JS, Song GS, Son DW

Syringomyelia associated with tuberculous meningitis is an extremely rare condition. Only a few studies have reported clinical experience with syringomyelia as a late complication of tuberculous meningitis. Twenty-six years after...
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Hypopituitarism Presenting as Osteoporotic Fracture after Cured Tuberculous Meningitis

Lee JY, Kim MJ, Kim MA, Kwon SH, Kim EK, Lee KA

Tuberculous meningitis is a well-known cause of hypothalamic pituitary dysfunction. However, deficiencies of anterior pituitary hormones may only become evident years after recovery because symptoms are of insidious-onset and nonspecific....
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En Plaque Tuberculoma: a Case Report

Kim YE, Lee D, Hwang H, Kim M

In Korea, tuberculosis is still common disease. Central nervous system tuberculosis can manifest in a variety of forms, including tuberculous meningitis, tuberculous cerebritis, tuberculoma, tuberculous abscess, and miliary tuberculosis. Although...
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Possible Tuberculous Meningitis Complicated with Optic Neuritis

Lee J, Kim HC, Bae SY, Lee D, Park KM

No abstract available.
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Procalcitonin as a Diagnostic and Prognostic Factor for Tuberculosis Meningitis

Kim J, Kim SE, Park BS, Shin KJ, Ha SY, Park J, Kim SE, Park KM

BACKGROUND AND PURPOSE: We investigated the potential role of serum procalcitonin in differentiating tuberculosis meningitis from bacterial and viral meningitis, and in predicting the prognosis of tuberculosis meningitis. METHODS: This was...
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Intradural Extramedullary Tuberculoma of the Spinal Cord Following Tuberculous Meningitis

Jeong DK, Kwon YM

Intradural extramedullary tuberculoma of the spinal cord (IETSC) is an uncommon disease which can occurs secondary to tuberculous meningitis. A 31-year-old woman was diagnosed as tuberculous meningitis after mental disorientation....
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Outcomes and Use of Therapeutic Drug Monitoring in Multidrug-Resistant Tuberculosis Patients Treated in Virginia, 2009-2014

Heysell SK, Moore JL, Peloquin C, Ashkin D, Houpt ER

BACKGROUND: Reports of therapeutic drug monitoring (TDM) for second-line medications to treat multidrug-resistant tuberculosis (MDR-TB) remain limited. METHODS: A retrospective cohort from the Virginia state tuberculosis (TB) registry, 2009-2014, was analyzed...
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Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis

Park KH, Lee MS, Lee SO, Choi SH, Kim YS, Woo JH, Kang JK, Lee SA, Kim SH

BACKGROUND/AIMS: The goal of this study was to monitor tuberculosis (TB)-specific T-cell responses in cerebrospinal fluid-mononuclear cells (CSF-MCs) and peripheral blood mononuclear cells (PBMCs) in patients with tuberculous meningitis (TBM)...
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A Case of Serum Sickness-Like Reaction and Anaphylaxis - Induced Simultaneously by Rifampin

Kim DH, Choi YH, Kim HS, Yu JE, Koh YI

Rifampin is commonly used as a first-line anti-tuberculosis drug, but it can induce a serum sickness-like reaction or anaphylaxis. However, it is possible for 1 drug antigen to induce 2...
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A case of pseudomembranous colitis associated with antituberculosis therapy in a patient with tuberculous meningitis

Kim MJ, Jeong HW, Choi YR

  • KMID: 2168989
  • J Biomed Res.
  • 2014 Mar;15(1):44-48.
Pseudomembranous colitis (PMC) is known to be associated with the long-term administration of antibiotics, which alter normal gastrointestinal flora and allow overgrowth of Clostridium difficile. However, antituberculosis agents are rarely...
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Hyponatremia in Children with Central Nervous System Infections

Kim SG, Nam SO, Kim YM, Yeon GM, Lee YJ

  • KMID: 1961829
  • J Korean Child Neurol Soc.
  • 2013 Sep;21(3):143-151.
PURPOSE: To compare the effect of different etiologies in children with central nervous system (CNS) infections on the incidence of initial and hospital-acquired hyponatremia (IH and HAH) (plasma sodium concentration,...
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