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The Role of Leptin in the Association between Obesity and Psoriasis

Hwang J, Yoo JA, Yoon H, Han T, Yoon J, An S, Cho JY, Lee J

Adipose tissue secretes many adipokines which contribute to various metabolic processes, such as blood pressure, glucose homeostasis, inflammation and angiogenesis. The biology of adipose tissue in an obese individual is...
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Outbreak investigation: transmission of COVID-19 started from a spa facility in a local community in Korea

Han T

OBJECTIVES: In Korea, there have been 10,480 confirmed cases of coronavirus disease 2019 (COVID-19) as of April 11, 2020. We investigated the transmission of COVID-19 in a cluster of cases. METHODS:...
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YH18968, a Novel 1,2,4-Triazolone G-Protein Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes Mellitus

Han T, Lee BM, Park YH, Lee DH, Choi HH, Lee T, Kim H

G protein-coupled receptor 119 (GPR119) is expressed in the pancreas and gastrointestinal tract, and its activation promotes insulin secretion in the beta cells of the pancreatic islets as well as...
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Avoiding student infection during a Middle East respiratory syndrome (MERS) outbreak: a single medical school experience

Park SW, Jang HW, Choe YH, Lee KS, Ahn YC, Chung MJ, Lee KS, Lee K, Han T

PURPOSE: In outbreaks of infectious disease, medical students are easily overlooked in the management of healthcare personnel protection although they serve in clinical clerkships in hospitals. In the early summer...
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Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells

Hu D, Zou H, Han T, Xie J, Dai N, Zhuo L, Gu J, Bian J, Yuan Y, Liu X, Liu Z

Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis...
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Humanities in medical education: between reduction and integration

Han T

Reductive logic has been a major reasoning style in development of modern biomedical sciences. However, when "medical humanities" is developed by reductive reasoning, integrative and holistic values of humanities tend...
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The micosporine-like amino acids-rich aqueous methanol extract of laver (Porphyra yezoensis) inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes

Kim H, Lee Y, Han T, Choi EM

BACKGROUND/OBJECTIVES: Increased mass of adipose tissue in obese persons is caused by excessive adipogenesis, which is elaborately controlled by an array of transcription factors. Inhibition of adipogenesis by diverse plant-derived...
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Juvenile Obesity Aggravates Disease Severity in a Rat Model of Atopic Dermatitis

Jeong KY, Lee J, Li C, Han T, Lee SB, Lee H, Back SK, Na HS

PURPOSE: There is increasing epidemiological evidence of an association between childhood obesity and atopic dermatitis, but little is known about the underlying mechanism(s). In the present study, we used a...
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Analysis of Predictive Factors for Lung Injury after Forward-Planned Intensity-Modulated Radiotherapy in Whole Breast Irradiation

Kim H, Bae H, Lee MY, Cheong KH, Kim KJ, Han T, Kang SK, Park S, Hwang T, Yoon JW, Kim LS

  • KMID: 2353086
  • J Breast Cancer.
  • 2014 Mar;17(1):69-75.
PURPOSE: This study was performed to assess frequency, timings of occurrence, and predictors of radiologic lung damage (RLD) after forward-planned intensity-modulated radiotherapy (FIMRT) for whole breast irradiation. METHODS: We retrospectively reviewed...
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Convolution-Superposition Based IMRT Plan Study for the PTV Containing the Air Region: A Prostate Cancer Case

Kang SK, Yoon JW, Park S, Hwang T, Cheong KH, Han T, Kim H, Lee MY, Kim KJ, Bae H

In prostate IMRT planning, the planning target volume (PTV), extended from a clinical target volume (CTV), often contains an overlap air volume from the rectum, which poses a problem inoptimization...
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Evaluation of the Radiochromic Film Dosimetry for a Small Curved Interface

Kang SK, Park S, Hwang T, Cheong KH, Han T, Kim H, Lee MY, Kim KJ, Bae H

  • KMID: 2315728
  • Prog Med Phys.
  • 2012 Dec;23(4):234-238.
A tumor on the eyelid is often treated using a high-energy electron beam, with a metallic eye shield inserted between the eyelid and the eyeball to preserve the patient's sight....
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The Effect of Early Escharectomy on Pro- and Antiinflammatory Cytokines in Major Burn Patients

Moon J, Hur J, Chun S, Kim J, Park S, Kwon J, Woo C, Kwak I, Han T, Kim K

BACKGROUND: Early escharectomy has been shown to improve survival rates and treatment outcomes in major burn patients. However, its mechanism, especially in human immune systems, has not been...
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MR Imaging of Disseminated Tuberculosis of the Brain in a Patient with Miliary Tuberculosis: Initial Findings and Changes Six Months after Antituberculous Therapy

Jang JH, Lim JW, Jung SL, Choeh K, Han T

  • KMID: 2207111
  • J Korean Pediatr Soc.
  • 2002 Dec;45(12):1596-1600.
A 23-month-old girl visited with chronic cough and her chest radiograph showed miliary tuberculosis. There was no neurological abnormality. But CSF findings showed WBC 22/mm3(lymphocyte 20%, neutrophil 80%) and positive...
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Annual Report on External Quality Assessment in Inborn Error of Metabolism in Korea (1999)

Kim J, Kwon K, Kim C, Min W, Park S, Han T, Song J, Lee S, Lee E, Choi T

  • KMID: 1561314
  • J Clin Pathol Qual Control.
  • 2000 Jun;22(1):139-152.
Two trials of external quality assessment for inborn error of metabolism was performed in 1999. In Trial 1, 6 specimens for neonatal screening test were distributed to 56 laboratories with...
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Intracellular Calcium Alterations Induced during Reperfusion Injury are Altered by Local Anesthetics and Hypothermia

Kim MH, Kim YH, Han T, Shin B

No abstract available.
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