J Korean Rheum Assoc.
2000 Jun;7(2):196-199.
Two Cases of Allergic Reactions to Mesna which Imitate Malar Rash
- Affiliations
-
- 1Eulji University.
- 2The Hospital for Rheumatic Diseases, Hanyang University, Seoul, Korea.
Abstract
- Hemorrhagic cystitis is potentially life-threatening sequellae of chemotherapy using oxazaphosphorine alkylating agents (cyclophosphamide and ifosfamide). Mesna contains a sulfhydryl group that is believed to bind acrolein within the urinary collecting system and reduce the hemorrhagic cystitis without affecting the chemotherapeutic potential. To date, about thirty cases of hypersensitivity or allergic reactions of the delayed and urticarial type associated with mesna have been reported. We reported two patients with systemic lupus erythematosus who developed facial rash and flushing associated with mesna which imitate malar rash.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Fixed Drug Eruption Caused by Mesna
- Acute urticarial rash after COVID-19 vaccination containing Polysorbate 80
- Chronic Cyclophosphamide Induced Cystitis that is Improved by Mesna
- Allergic reactions after intravenous injection of methylprednisolone: A case report
- Radioprotective Effect of Mesna on Mouse Testis
