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The Fate of Partially Thrombosed Intracranial Aneurysms Treated with Endovascular Intervention

Lee J, Cho WS, Yoo RE, Yoo DH, Cho YD, Kang HS, Kim JE

Objective : The fate of partially thrombosed intracranial aneurysms (PTIAs) is not well known after endovascular treatment. The authors aimed to analyze the treatment outcomes of PTIAs. Methods : We retrospectively...
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Risk of Tuberculosis Development in Patients with Rheumatoid Arthritis Receiving Targeted Therapy:a Prospective Single Center Cohort Study

Song YJ, Cho SK, Kim H, Kim HW, Nam E, Bae SC, Yoo DH, Sung YK

Background: Patients with rheumatoid arthritis (RA) undergoing targeted therapy have a higher risk of developing tuberculosis (TB). This requires diagnosis and treatment of latent tuberculosis infection (LTBI). We aimed to...
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KOBIO, the First Web-based Korean Biologics Registry Operated With a Unified Platform Among Distinct Disease Entities

Kim J, Koh JH, Choi SJ, Jeon CH, Kwok SK, Kim SK, Choi CB, Lee J, Lee C, Nam EJ, Park YB, Lee SS, Kim TH, Park SH, Choe JY, Koh EM, Yoo DH, Song YW, Kim HA, Shin K

The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying...
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Fracture Risk and Its Prevention Patterns in Korean Patients with Polymyalgia Rheumatica: a Retrospective Cohort Study

Nam B, Sung YK, Choi CB, Kim TH, Jun JB, Bae SC, Yoo DH, Cho SK

Background: To evaluate the incidence of fractures and fracture risk factors in Korean patients with polymyalgia rheumatica (PMR). Methods: All PMR patients who visited a rheumatology clinic at a tertiary referral...
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Efficacy and Safety of Rituximab in Korean Patients with Refractory Inflammatory Myopathies

Ahn GY, Suh CH, Kim YG, Park YB, Shim SC, Lee SH, Lee SS, Bae SC, Yoo DH

Background: Rituximab (RTX), a monoclonal antibody that selectively binds to CD20+ B cells, showed favorable outcomes in patients with idiopathic inflammatory myopathies (IIM) in small case series, but the evidence...
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Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity

Shin K, Kim SS, Lee SH, Hong SJ, Choi SJ, Choe JY, Lee SG, Cha HS, Lee EY, Park SH, Hur JW, Na SS, Suh CH, So MW, Choi SW, Sheen DH, Park W, Lee SS, Ryu WH, Kim JS, Song JS, Lee HS, Kim SH, Yoo DH

Background/Aims: The objective of this study was to compare changes in the simplified disease activity index (SDAI) between biologic (b) and conventional (c) disease-modifying antirheumatic drugs (DMARD) users with seropositive...
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De Novo Intracranial Aneurysms Detected on Imaging Follow-Up of Coiled Aneurysms in a Korean Population

Yeon EK, Cho YD, Yoo DH, Lee SH, Kang HS, Cho WS, Kim JE, Han MH

OBJECTIVE: Coiled aneurysms are known to recanalize over time, making follow-up evaluations mandatory. Although de novo intracranial aneurysms (DNIAs) are occasionally detected during routine patient monitoring, such events have not...
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Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis

Baek HJ, Lim MJ, Park W, Park SH, Shim SC, Yoo DH, Kim HA, Lee SK, Lee YJ, Park YE, Cha HS, Song YW

BACKGROUND/AIMS: To investigate the efficacy and safety of tocilizumab (TCZ) humanized anti-interleukin-6 receptor monoclonal antibody, in Korean patients with active rheumatoid arthritis (RA) refractory to conventional disease modifying anti-rheumatic drugs...
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Factors associated with time to diagnosis from symptom onset in patients with early rheumatoid arthritis

Cho SK, Kim D, Won S, Lee J, Choi CB, Choe JY, Hong SJ, Jun JB, Kim TH, Koh E, Lee HS, Lee J, Yoo DH, Yoon BY, Bae SC, Sung YK, Korean Observational Study Network for Arthritis (KORONA) Investigators

BACKGROUND/AIMS: To identify the factors associated with time to diagnosis after symptom onset in patients with early rheumatoid arthritis (RA). METHODS: Early RA patients with ≤ 1 year of disease duration...
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A POLG2 Homozygous Mutation in an Autosomal Recessive Epilepsy Family Without Ophthalmoplegia

Lee SJ, Kanwal S, Yoo DH, Park HR, Choi BO, Chung KW

No abstract available.
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Incidence and Prevalence of Idiopathic Inflammatory Myopathies in Korea: a Nationwide Population-based Study

Cho SK, Kim H, Myung J, Nam E, Jung SY, Jang EJ, Yoo DH, Sung YK

BACKGROUND: This study aimed to estimate the incidence and prevalence of idiopathic inflammatory myopathies (IIM) and associated comorbidities in Korea from 2006 to 2015. METHODS: IIM between 2004 to 2015 were...
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Symptomatic Retinal Artery Occlusion after Angioplasty and Stenting of the Carotid Artery: Incidence and Related Risk Factors

An SJ, Cho YD, Lee J, Mun JH, Yoo DH, Kang HS, Yang YJ, Han MH

OBJECTIVE: Retinal artery occlusion (RAO) is rarely seen as a complication in patients undergoing carotid artery stenting (CAS); hence, its characteristics have not been documented in detail. This study aimed...
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Effectiveness and Safety of Tacrolimus in Patients with Active Rheumatoid Arthritis with Inadequate Response to Disease-modifying Anti-rheumatic Drugs: The TREASURE Study

Sheen DH, Hong SJ, Lee SH, Lee HS, Chung WT, Jiang H, Lee S, Yoo DH

OBJECTIVE: Evaluate effectiveness/safety of tacrolimus in patients in Korea with active rheumatoid arthritis (RA) and unsuccessful response to disease-modifying anti-rheumatic drugs (DMARDs). METHODS: Open-label, single-arm, non-comparative, 24-week, Phase-IV study in patients...
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Isoniazid treatment for latent tuberculosis infection is tolerable for rheumatoid arthritis patients receiving tumor necrosis factor inhibitor therapy

Sung YK, Cho SK, Kim D, Won S, Choi CB, Kim TH, Jun JB, Yoo DH, Bae SC

BACKGROUND/AIMS: To evaluate the impact of isoniazid (INH) treatment for latent tuberculosis infection (LTBI) on the development of liver function test (LFT) abnormality and the persistence of tumor necrosis factor...
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Endovascular Treatment of Bilateral Cavernous Sinus Dural Arteriovenous Fistula: Therapeutic Strategy and Follow-Up Outcomes

Rhim JK, Cho YD, Yoo DH, Kang HS, Cho WS, Kim JE, Cho MJ, Hwang G, Kwon OK, Han MH

OBJECTIVE: Bilateral cavernous sinus dural arteriovenous fistula (CSdAVF) is very rare, even in Asian countries. The research intended to present clinical and radiologic outcomes of treating such fistulas through endovascular...
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Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea

Song JJ, Song YW, Bae SC, Cha HS, Choe JY, Choi SJ, Kim HA, Kim J, Kim SS, Lee CK, Lee J, Lee SH, Lee SS, Lee SK, Lee SW, Park SH, Park W, Shim SC, Suh CH, Yoo B, Yoo DH, Yoo WH

BACKGROUND: To evaluate the therapeutic benefits of the treat-to-target (T2T) strategy for Asian patients with early rheumatoid arthritis (RA) in Korea. METHODS: In a 1-year, multicenter, open-label strategy trial, 346 patients...
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A Novel Nonsense Mutation in Leucine-Rich, Glioma-Inactivated-1 Gene as the Underlying Cause of Familial Temporal Lobe Epilepsy

Kanwal S, Yoo DH, Tahir S, Lee SJ, Lee MH, Choi BO, Chung KW

No abstract available.
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Intracranial Mirror Aneurysms: Anatomic Characteristics and Treatment Options

Choi HH, Cho YD, Yoo DH, Lee J, Mun JH, An SJ, Kang HS, Cho WS, Kim JE, Han MH

OBJECTIVE: Mirror aneurysms are generally considered as a subset of multiple aneurysms, defined as aneurysms occurring bilaterally and symmetrically on the same-named vessels. Although not infrequent, the characteristics of mirror...
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Prevalence and Associated Factors for Non-adherence in Patients with Rheumatoid Arthritis

Kim D, Choi JY, Cho SK, Choi CB, Bang SY, Cha HS, Choe JY, Chung WT, Hong SJ, Kim TH, Kim TJ, Koh E, Lee HS, Lee J, Lee SS, Lee SW, Park SH, Shim SC, Yoo DH, Yoon BY, Bae SC, Sung YK

OBJECTIVE: To estimate the prevalence of non-adherence to rheumatoid arthritis (RA) medication and identify the associated factors for non-adherence in RA patients. METHODS: Among the KORean Observational study Network for Arthritis...
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Impact of early diagnosis on functional disability in rheumatoid arthritis

Kim D, Choi CB, Lee J, Cho SK, Won S, Bang SY, Cha HS, Choe JY, Chung WT, Hong SJ, Jun JB, Jung YO, Kim J, Kim SK, Kim TH, Kim TJ, Koh E, Lee HS, Lee J, Lee J, Lee SH, Lee SS, Lee SW, Shim SC, Yoo DH, Yoon BY, Sung YK, Bae SC, KORONA investigators

BACKGROUND/AIMS: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients. METHODS: A total of 4,540 RA patients were enrolled as part...
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