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Chronic Cyclophosphamide Induced Cystitis that is Improved by Mesna

Woo W, Lee C, Kim S, Kwon O, Ahn S, Seong B

  • KMID: 2061121
  • Korean J Urol.
  • 2005 Apr;46(4):420-421.
Cyclophosphamide is alkylating agent used in the treatment of various solid tumors. Mucosal irritation by acrolein, the metabolite of cyclophosphamide, is believed to cause various symptoms of cystitis. The thiol...
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Acrolein Is a Hazardous Air Pollutant

  • KMID: 2299509
  • Korean J Asthma Allergy Clin Immunol.
  • 2011 Jun;31(2):84-90.
Acrolein (2-propenal) is a highly reactive alpha, beta unsaturated aldehyde, and a product of lipid peroxidation reactions. It is formed from carbohydrates, amino acids, vegetable oils and animal fats during...
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Curcumin Attenuates Acrolein-induced COX-2 Expression and Prostaglandin Production in Human Umbilical Vein Endothelial Cells

Lee SE, Park HR, Jeon S, Han D, Park YS

OBJECTIVE: Inflammation is crucial to limiting vascular disease. Previously we reported that acrolein, a known toxin in tobacco smoke, might play an important role in the progression of atherosclerosis via...
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Two Cases of Allergic Reactions to Mesna which Imitate Malar Rash

Seo JC, Bae SC, Shim SC, Kim TH, Jun JB, Jung SS, Lee IH, Yoo DH, Kim SY

  • KMID: 2202479
  • J Korean Rheum Assoc.
  • 2000 Jun;7(2):196-199.
Hemorrhagic cystitis is potentially life-threatening sequellae of chemotherapy using oxazaphosphorine alkylating agents (cyclophosphamide and ifosfamide). Mesna contains a sulfhydryl group that is believed to bind acrolein within the urinary...
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Study of the removal difference in indoor particulate matter and volatile organic compounds through the application of plants

Hong SH, Hong J, Yu J, Lim Y

This study was conducted to evaluate the ability of plants to purify indoor air by observing the effective reduction rate among pollutant types of particulate matter (PM) and volatile organic...
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A Case of Occupational Asthma in a Plastic Injection Process Worker

Lee JS, Kwak HS, Choi BS, Park SY

  • KMID: 2379971
  • Ann Occup Environ Med.
  • 2013 ;25(1):25.
OBJECTIVES: We report a case of death due to asthma attack in a plastic injection process worker with a history of asthma. METHODS: To assess task relevance, personal history including occupational...
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Hazards Exposed to Firefighters in Fire: Physical, Chemical, and Biologic factors

Kim JM, Lee HJ

According to National Emergency Management Agency in Korea, numbers of death and injured in firefighters were 34 and 1,555 persons, respectively, between 2003 and 2007. Firefighting is a very dangerous...
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Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases

Park MH, Igarashi K

  • KMID: 2170679
  • Biomol Ther.
  • 2013 Jan;21(1):1-9.
Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are essential for eukaryotic cell growth. These polycations interact with negatively charged molecules such as DNA, RNA, acidic proteins...
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A Case of Bladder Cancer in a Patient with Systemic Lupus Erythematosus Treated with Oral Cyclophosphamide

Kim KJ, Kim WT, Kim SY, Hong JH, Kim HR, Yoon CH, Lee SH, Park SH, Kim HY

  • KMID: 1899477
  • J Korean Rheum Assoc.
  • 2004 Sep;11(3):286-291.
Cyclophosphamide, a cytotoxic alkylating agent, is widely used in various benign diseases like systemic lupus erythematosus (SLE), Wegener's granulomatosis, rheumatoid arthritis, nephrotic syndrome as well as in malignancies and organ...
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Effect of Imipramine on the Contractility of Single Cells Isolated for Canine Detrusor

Huh CW, Lee KY, Kim WJ

The objective of this study was to establish a good methodology to isolate single smooth muscle cells that are alive and respond properly to pharmacological agents. Canine urinary bladders were...
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Gabapentin Attenuates the Activation of Transient Receptor Potential A1 by Cinnamaldehyde

Bang S, Yoo S, Hwang SW

Gabapentin is used as an effective drug for relieving pain, but the main mechanism is still unclear. Recently, voltage-gated Ca2+ channel subunits are suggested for the main target for the...
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