- Chronic Cyclophosphamide Induced Cystitis that is Improved by Mesna
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Woo W, Lee C, Kim S, Kwon O, Ahn S, Seong B
- KMID: 2061121
- Korean J Urol.
- 2005 Apr;46(4):420-421.
Cyclophosphamide is alkylating agent used in the treatment of various solid tumors. Mucosal irritation by acrolein, the metabolite of cyclophosphamide, is believed to cause various symptoms of cystitis. The thiol... -
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- Fixed Drug Eruption Caused by Mesna
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Kang YS, Lee JH, Kim SY, Kim GM
- KMID: 2301706
- Korean J Dermatol.
- 2012 Feb;50(2):138-141.
A fixed drug eruption (FDE) is a cutaneous reaction caused by various drugs. Mesna is used to decrease urotoxic side effect of cyclophosphamide and there have been no previously reported... -
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- Radioprotective Effect of Mesna on Mouse Testis
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Ryu S, Kim JC, Kim SB, Park IK
- KMID: 1941517
- J Korean Soc Ther Radiol.
- 1990 Dec;8(2):145-150.
Mesna has been used with ifosfamide to prevent urotoxicity in the treatment of testicular cancers. This drug also protected the toxicities of adriamycin without compromising cytostatic activity. With n idea... -
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- Two Cases of Allergic Reactions to Mesna which Imitate Malar Rash
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Seo JC, Bae SC, Shim SC, Kim TH, Jun JB, Jung SS, Lee IH, Yoo DH, Kim SY
- KMID: 2202479
- J Korean Rheum Assoc.
- 2000 Jun;7(2):196-199.
Hemorrhagic cystitis is potentially life-threatening sequellae of chemotherapy using oxazaphosphorine alkylating agents (cyclophosphamide and ifosfamide). Mesna contains a sulfhydryl group that is believed to bind acrolein within the urinary... -
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- The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats
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Li X, Yang S, Lv X, Sun H, Weng J, Liang Y, Zhou D
- KMID: 2288550
- J Gynecol Oncol.
- 2013 Apr;24(2):177-185.
- doi: 10.3802/jgo.2013.24.2.177
OBJECTIVE: Cisplatin is a widely used chemotherapeutic agent in the treatment of cancers in clinic; but it often induces adverse effects on ovarian functions such as reduced fertility and premature... -
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- Fatal Ifosfamide-Induced Metabolic Encephalopathy in Patients with Recurrent Epithelial Ovarian Cancer: Report of Two Cases
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Shin YJ, Kim JY, Moon JW, You RM, Park JY, Nam JH
- KMID: 2167570
- Cancer Res Treat.
- 2011 Dec;43(4):260-263.
Central nervous system (CNS) toxicity has been reported in approximately 10-30% of patients receiving intravenous infusions of ifosfamide. Encephalopathy is a rare but serious CNS adverse reaction in these patients,... -
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- Inhibition of melanogenesis by sodium 2-mercaptoethanesulfonate
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Kim JH, Oh CT, Kwon TR, Kim JH, Bak DH, Kim H, Park WS, Kim BJ
- KMID: 2471036
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):149-156.
- doi: 10.4196/kjpp.2020.24.2.149
Sodium 2-mercaptoethanesulfonate (mesna) is a protective agent that is widely used in medicine because of its antioxidant effects. Recently, reactive oxygen species (ROS) were shown to increase pigmentation. Thus, ROS... -
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- BK virus-associated hemorrhagic cystitis after pediatric stem cell transplantation
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Han SB, Cho B, Kang JH
- KMID: 2284640
- Korean J Pediatr.
- 2014 Dec;57(12):514-519.
- doi: 10.3345/kjp.2014.57.12.514
Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of... -
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- Clinical Efficacy of Ifosfamide-Based Regimen in Refractory of Relapsed Ovarian Cancer
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Lee HP, Park NH, Kim JW, Park SY, Song YS, Kang SB
- KMID: 1890522
- Korean J Gynecol Oncol Colposc.
- 1996 Dec;7(4):263-269.
This phase II study aimed to assess the clinical activity and toxicity of ifosfamide based regimen in patients with epithelial ovarian cancer, relapsed or refractory to cisplatin-containing combination chemotherapy. From... -
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- Malignant Schwannoma arising from Neuroflbromatosis (von Recklinghausen's disease): A Report of Three Cases in the Spine
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Jeong ST, Song HR, Koo KH, Park HB, Ha SJ, Cho SH
- KMID: 2322789
- J Korean Soc Spine Surg.
- 1998 Nov;5(2):320-325.
STUDY DESIGN: Authors experienced three cases of malignant schwannoma arising from multiple neurofibromatosis and invading the vertebrae. OBJECTIVE: To report treatment results and preventive idea in three cases of malignant schwannoma... -
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- Phase II Study of Ifosfamide, Etoposide and Cisplatin(IEP) Chemotherapy for Advanced Non-Small Cell Lung Cancer
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Lee SN
- KMID: 1965085
- Ewha Med J.
- 1993 Dec;16(4):337-340.
- doi: 10.12771/emj.1993.16.4.337
To evaluste the efficacy and toxicity of IEP chemotherapy in locally advanced and metastatic non-small cell lung cancer, nineteen previously untreated patients with non-small cell lung cancer were studied. Patients received... -
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- Phase I Clinical Trial of Paclitaxel Plus Ifosfamide for the Patients with Refractory Ovarian Cancer
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Saw HS, Lee JK
- KMID: 1815306
- J Korean Cancer Assoc.
- 2000 Oct;32(5):895-903.
PURPOSE: Patients with advanced ovarian carcinoma and refractory to platinum based chemotherapy have a very poor prognosis and effective salvage regimens are needed. This study was conducted in order to... -
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- Ifosfamide and Etoposide in Relapsed Refractory Childhood Acute Lymphoblastic Leukemia
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Kim SS, Cho B, Jeong DC, Kim HK
- KMID: 2072458
- Korean J Pediatr Hematol Oncol.
- 1997 Apr;4(1):90-97.
BACKGROUND: The prognosis for children with relapsed acute lymphoblastic leukemia remains dismal. Ifosfamide has previously been shown to be active as a single agent and in combination with doxorubicin, etoposide,... -
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- Endometrial stromal sarcoma associated with extrauterine endometriosis: a case report and literature review
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Park SK, Lee SJ, Kwon HS, Sohn IS, Lee JY, Kim SN, Cha YJ, Lim SD
- KMID: 1979506
- Korean J Gynecol Oncol.
- 2008 Mar;19(1):87-92.
- doi: 10.3802/kjgo.2008.19.1.87
Endometrial stromal sarcoma (ESS) that arises from extrauterine endometriosis is a rare form of malignancy. We report the case of a 37-year-old ESS patient with extrauterine endometriosis who was treated... -
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- Reversible Proximal Renal Tubular Dysfunction after One-Time Ifosfamide Exposure
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Kim YI, Yoon JY, Hwang JE, Shim HJ, Bae WK, Cho SH, Chung IJ
- KMID: 2165959
- Cancer Res Treat.
- 2010 Dec;42(4):244-246.
The alkylating agent ifosfamide is an anti-neoplastic used to treat various pediatric and adult malignancies. Its potential urologic toxicities include glomerulopathy, tubulopathy and hemorrhagic cystitis. This report describes a case... -
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- Combination chemotherapy with vinorelbine and ifosfamide for advanced non-small cell lung cancer
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Cho EK, Hong SH, Bang SM, Lee HK, Park JW, Jeong SH, Nam G, Shin DB, Lee JH
- KMID: 1600623
- Korean J Med.
- 2001 Jan;60(1):70-76.
BACKGROUND: Although cisplatin (CDDP)-based chemotherapy is currently considered to be the most active treatment for advanced non-small cell lung cancer (NSCLC), ultimate prognosis still remains poor. More effective cytotoxic agents... -
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- Treatment outcomes of IMEP as a front-line chemotherapy for patients with peripheral T-cell lymphomas
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Lee JY, Lee SM, Choi MY, Kim KH, Joo YD, Im SN, Lee WS
- KMID: 2353500
- Blood Res.
- 2016 Sep;51(3):187-192.
- doi: 10.5045/br.2016.51.3.187
BACKGROUND: This study aimed to assess the treatment outcomes of ifosphamide, mesna, etoposide, and prednisolone (IMEP) combination regimen as a front-line chemotherapy in patients with peripheral T-cell lymphomas (PTCLs). METHODS: Clinical... -
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- Combination Chemotherapy with Vinorelbine and Ifosfamide in Patients with Advanced Non-Small Cell Lung Cancer
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Kim SG, Kim SH, Kwon HC, Lee KH, Kim JS, Kim HJ
- KMID: 2174991
- J Korean Cancer Assoc.
- 2001 Apr;33(2):163-167.
PURPOSE: We conducted a phase II study of vinorelbine and ifosfamide combination chemotherapy in patients with advanced or recurrent non-small cell lung cancer (NSCLC) to evaluate response rate, response duration,... -
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- Combination Chemotherapy with Cisplatin , Etoposide , and Ifosfamide ( PIE ) in the Advanced Non - Small Cell Lung Cancer
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Shin SW, Kim BS, Shin JJ, Kim YH, Kang KH, Choi YH, Kim KT, Kim JS
- KMID: 2329112
- J Korean Cancer Assoc.
- 1998 Apr;30(2):225-230.
PURPOSE: Combination chemotherapy with cisplatin and etoposide have been considered as one of the chemotherpy regimen for non small cell lung cacer(NSCLC) with the response rate of 20~40%. Ifosfamide is... -
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- The Effect of Combination Chemotherapy with Vinorelbine, Carboplatin, and Ifosfamide in Patients with Advanced Non-Small Cell Lung Cancer
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Lee YW, Ryoo BY, Kim TY, Kim BS, Park YH, Hong HJ, Kwag JY, Lee SW, Kang YK
- KMID: 2175134
- J Korean Cancer Assoc.
- 1999 Dec;31(6):1227-1235.
PURPOSE: Despite recent advances in chemotherapy, the treatment outcome of advanced non-small cell lung cancer (NSCLC) remains poor and NSCLC is still the predominant source of cancer-related mortality in worldwide.... -
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