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Clinical and Genetic Risk Factors Associated With the Presence of Lupus Nephritis

Shin JM, Kim D, Kwon YC, Ahn GY, Lee J, Park Y, Lee YK, Lee TH, Park DJ, Song YJ, Ha E, Kim K, Bang SY, Choi CB, Lee HS, Bae SC

Objective To elucidate whether clinical features and the weighted genetic risk score (wGRS) were associated with the presence of lupus nephritis (LN). Methods We retrospectively divided patients with systemic lupus...
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Mortality in Korean Patients With Rheumatoid Arthritis

Lee YK, Bae SC

Rheumatoid arthritis (RA) is a chronic inflammatory disease in which the abnormal immune system causes arthritis. We reviewed previous studies about the mortality and causes of death in Korean patients...
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Characteristics in Pediatric Patients with Coronavirus Disease 2019 in Korea

Seon JY, Jeon WH, Bae SC, Eun BL, Choung JT, Oh IH

Background: Based on the reports of low prevalence and severity of pediatric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, the Korean government has released new SARS-CoV-2 infection response and...
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Risk Factors of Outcomes of COVID-19 Patients in Korea: Focus on Early Symptoms

Jang SY, Seon JY, Eun BL, Koh SB, Yoo JH, Lee WY, Yum HK, Yoon SJ, Oh IH, Bae SC, Chang SG

Background: Coronavirus disease 2019 (COVID-19) has spread around the globe, and it is important to determine the risk factors of death in the general population. Our study aimed to determine...
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Risk of Tuberculosis Development in Patients with Rheumatoid Arthritis Receiving Targeted Therapy:a Prospective Single Center Cohort Study

Song YJ, Cho SK, Kim H, Kim HW, Nam E, Bae SC, Yoo DH, Sung YK

Background: Patients with rheumatoid arthritis (RA) undergoing targeted therapy have a higher risk of developing tuberculosis (TB). This requires diagnosis and treatment of latent tuberculosis infection (LTBI). We aimed to...
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Fracture Risk and Its Prevention Patterns in Korean Patients with Polymyalgia Rheumatica: a Retrospective Cohort Study

Nam B, Sung YK, Choi CB, Kim TH, Jun JB, Bae SC, Yoo DH, Cho SK

Background: To evaluate the incidence of fractures and fracture risk factors in Korean patients with polymyalgia rheumatica (PMR). Methods: All PMR patients who visited a rheumatology clinic at a tertiary referral...
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Efficacy and Safety of Rituximab in Korean Patients with Refractory Inflammatory Myopathies

Ahn GY, Suh CH, Kim YG, Park YB, Shim SC, Lee SH, Lee SS, Bae SC, Yoo DH

Background: Rituximab (RTX), a monoclonal antibody that selectively binds to CD20+ B cells, showed favorable outcomes in patients with idiopathic inflammatory myopathies (IIM) in small case series, but the evidence...
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Factors associated with time to diagnosis from symptom onset in patients with early rheumatoid arthritis

Cho SK, Kim D, Won S, Lee J, Choi CB, Choe JY, Hong SJ, Jun JB, Kim TH, Koh E, Lee HS, Lee J, Yoo DH, Yoon BY, Bae SC, Sung YK, Korean Observational Study Network for Arthritis (KORONA) Investigators

BACKGROUND/AIMS: To identify the factors associated with time to diagnosis after symptom onset in patients with early rheumatoid arthritis (RA). METHODS: Early RA patients with ≤ 1 year of disease duration...
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Mesenchymal Stem Cells Ameliorate Renal Inflammation in Adriamycin-induced Nephropathy

Kim HS, Lee JS, Lee HK, Park EJ, Jeon HW, Kang YJ, Lee TY, Kim KS, Bae SC, Park JH, Han SB

Mesenchymal stem cells (MSCs) ameliorate the renal injury in Adriamycin (ADR)-induced nephropathy, but the mechanisms underlying their efficacy remain incompletely understood. In this study, we demonstrated that MSCs increased the...
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Isoniazid treatment for latent tuberculosis infection is tolerable for rheumatoid arthritis patients receiving tumor necrosis factor inhibitor therapy

Sung YK, Cho SK, Kim D, Won S, Choi CB, Kim TH, Jun JB, Yoo DH, Bae SC

BACKGROUND/AIMS: To evaluate the impact of isoniazid (INH) treatment for latent tuberculosis infection (LTBI) on the development of liver function test (LFT) abnormality and the persistence of tumor necrosis factor...
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Strategies for the safe use of non-steroidal anti-inflammatory drugs

Ahn GY, Bae SC

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in various clinical situations, with excellent analgesic, anti-pyretic and anti-inflammatory effects. In addition to gastrointestinal bleeding, which was the first adverse effect to...
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Productivity Loss of Rheumatoid Arthritis Patients according to the Their Stages of the Disease Activity Score

Bae SC, Cha JH, Choe JY, Choi SJ, Cho SK, Chung WT, Joung CI, Jung YO, Kang YM, Kim DW, Kim J, Kim YJ, Lee CK, Lee HS, Lee J, Lee SH, Lee SH, Lee SS, Lee YA, Nah SS, Shim SC, Song GG, Suh CH, Won S, Yoo WH, Yoon BY

OBJECTIVE: Productivity loss was compared by 3-stage of disease activity and associations between higher disease activity and high productivity loss were identified. METHODS: Data were extracted from Rheumatoid Arthritis (RA) Patient-reported...
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Laboratory Management Status of Vestibular Function Test in Korea

Kim TS, Kim MJ, Kim BK, Kim HA, Bae DW, Bae M, Bae SC, Lee E, Jeon EJ

OBJECTIVES: This study was conducted to assess the current management status of the vestibular function test laboratories in Korea. METHODS: Questionnaire about the management status of the vestibular function test laboratories...
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Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea

Song JJ, Song YW, Bae SC, Cha HS, Choe JY, Choi SJ, Kim HA, Kim J, Kim SS, Lee CK, Lee J, Lee SH, Lee SS, Lee SK, Lee SW, Park SH, Park W, Shim SC, Suh CH, Yoo B, Yoo DH, Yoo WH

BACKGROUND: To evaluate the therapeutic benefits of the treat-to-target (T2T) strategy for Asian patients with early rheumatoid arthritis (RA) in Korea. METHODS: In a 1-year, multicenter, open-label strategy trial, 346 patients...
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Rapid onset of efficacy predicts response to therapy with certolizumab plus methotrexate in patients with active rheumatoid arthritis

Kang YM, Park YE, Park W, Choe JY, Cho CS, Shim SC, Bae SC, Suh CH, Cha HS, Koh EM, Song YW, Yoo B, Lee SS, Park MC, Lee SH, Arendt C, Koetse W, Lee SK

BACKGROUND/AIMS: The objective of this study was to determine the efficacy and safety of add-on therapy with certolizumab pegol (CZP) in active rheumatoid arthritis (RA) patients of a single ethnicity. METHODS:...
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Prevalence and Associated Factors for Non-adherence in Patients with Rheumatoid Arthritis

Kim D, Choi JY, Cho SK, Choi CB, Bang SY, Cha HS, Choe JY, Chung WT, Hong SJ, Kim TH, Kim TJ, Koh E, Lee HS, Lee J, Lee SS, Lee SW, Park SH, Shim SC, Yoo DH, Yoon BY, Bae SC, Sung YK

OBJECTIVE: To estimate the prevalence of non-adherence to rheumatoid arthritis (RA) medication and identify the associated factors for non-adherence in RA patients. METHODS: Among the KORean Observational study Network for Arthritis...
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ABCG2 Polymorphism Is Associated with Hyperuricemia in a Study of a Community-Based Korean Cohort

Son CN, Bang SY, Kim SH, Sung YK, Bae SC, Jun JB

The purpose of the present study was to find novel loci associated with hyperuricemia using data from a genome-wide association study (GWAS) conducted on healthy Koreans. We conducted a GWAS...
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Impact of early diagnosis on functional disability in rheumatoid arthritis

Kim D, Choi CB, Lee J, Cho SK, Won S, Bang SY, Cha HS, Choe JY, Chung WT, Hong SJ, Jun JB, Jung YO, Kim J, Kim SK, Kim TH, Kim TJ, Koh E, Lee HS, Lee J, Lee J, Lee SH, Lee SS, Lee SW, Shim SC, Yoo DH, Yoon BY, Sung YK, Bae SC, KORONA investigators

BACKGROUND/AIMS: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients. METHODS: A total of 4,540 RA patients were enrolled as part...
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Long-term Outcomes of Autologous Peripheral Blood Stem Cell Transplantation for Refractory Rheumatic Diseases

Lee S, Bae SC, Jun JB, Choi CB

OBJECTIVE: We investigated the long-term outcomes of autologous peripheral blood stem cell transplantation (PBSCT) to treat refractory rheumatic diseases. METHODS: Patients who underwent PBSCT for refractory rheumatic diseases at our institution...
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Atypical bone change of spine caused by epidural venous thrombosis in systemic lupus erythematosus with antiphospholipid syndrome

Kim JY, Lee S, Choi YY, Bae SC

No abstract available.
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