J Korean Radiol Soc.  1997 Jan;36(1):29-31.

Langerhans Cell Histiocytosis Involving Central Nervous System: A Case Report

Affiliations
  • 1Department of Diagnostic Radiology, College of Medicine, Hanyang University.
  • 2Department of Diagnostic Radiology, College of Medicine, Ulsan University.

Abstract

Langerhans cell histiocytosis(LCH) is a systemic disorder characterized by idiopathic proliferation of histiocytes in the reticuloendothelial system; CNS involvement outside the hypothalamus or pituitary gland is uncommon. We present a case of LCH involving the brainstem, cerebellum, and temporal lobes, and also showing hypothalamic involvement. The lesions were isointense or hypointense on T1WI and hyperintense on T2WI, and showed multifocal enhancing nodules on post-contrast CT and Gd-enhanced MRI.

Keyword

Brain, MR; Histiocytosis

MeSH Terms

Brain Stem
Central Nervous System*
Cerebellum
Histiocytes
Histiocytosis
Histiocytosis, Langerhans-Cell*
Hypothalamus
Magnetic Resonance Imaging
Mononuclear Phagocyte System
Pituitary Gland
Temporal Lobe
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