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An Enlarged Perivascular Space: Clinical Relevance and the Role of Imaging in Aging and Neurologic Disorders

Yim Y, Moon WJ

The perivascular space (PVS) of the brain, also known as Virchow-Robin space, consists of cerebrospinal fluid and connective tissues bordered by astrocyte endfeet. The PVS, in a word, is the...
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Correlation of Hemispatial Neglect with White Matter Tract Integrity: A DTI Study

Kwon BM, Lee JY, Ko N, Kim BR, Moon WJ, Choi DH, Lee J

We investigated the diffusion tensor image (DTI) parameters of superior longitudinal fasciculus (SLF) and inferior fronto-occipital fasciculus (IFOF), and their relationships with hemispatial neglect. Thirteen patients with first-ever ischemic stroke...
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Relationship Between Ipsilesional Upper Extremity Motor Function and Corpus Callosum Integrity in Patients With Unilateral Stroke: A Diffusion Tensor Imaging Study

Kwon BM, Lee Y, Lee HH, Ko N, Kim H, Kim BR, Moon WJ, Lee J

This study aims to investigate the relationship between ipsilesional upper extremity (UE) motor function and the integrity of the subregions of the corpus callosum in hemiparetic stroke patients with motor...
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Role of Cortico-ponto-cerebellar Tract from Supplementary Motor Area in Ataxic Hemiparesis of Supratentorial Stroke Patients

Ko N, Lee HH, Kim K, Kim BR, Moon WJ, Lee J

Cortical lesions of the supplementary motor area (SMA) are important in balance control and postural recovery in stroke patients, while the role of subcortical lesions of the SMA has not...
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Expert Opinions and Recommendations for the Clinical Use of Quantitative Analysis Software for MRI-Based Brain Volumetry

Lee JY, Park JE, Chung MS, Oh SW, Moon WJ, Aging and Neurodegeneration Imaging (ANDI) Study Group, Korean Society of Neuroradiology (KSNR)

The objective assessment of atrophy and the measurement of brain volume is important in the early diagnosis of dementia and neurodegenerative diseases. Recently, several MR-based volumetry software have been developed....
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Regional Differences in Blood-Brain Barrier Permeability in Cognitively Normal Elderly Subjects: A Dynamic Contrast-Enhanced MRI-Based Study

Ha IH, Lim C, Kim Y, Moon Y, Han SH, Moon WJ

Objective: This study aimed to determine whether there are regional differences in the blood-brain barrier (BBB) permeability of cognitively normal elderly participants and to identify factors influencing BBB permeability with...
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Evaluation of Reproducibility of Brain Volumetry between Commercial Software, Inbrain and Established Research Purpose Method, FreeSurfer

J, JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Background and Purpose We aimed to determine the intermethod reproducibility between the commercial software Inbrain (MIDAS IT) and the established research-purpose method FreeSurfer, as well as the effect of MRI...
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Comparison of Automated Brain Volume Measures by NeuroQuant vs. Freesurfer in Patients with Mild Cognitive Impairment: Effect of Slice Thickness

Yim Y, Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Purpose: This study aimed to examine the inter-method reliability and volumetric differences between NeuroQuant (NQ) and Freesurfer (FS) using T1 volume imaging sequence with different slice thicknesses in patients with...
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Clinically Available Software for Automatic Brain Volumetry: Comparisons of Volume Measurements and Validation of Intermethod Reliability

Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Objective: To compare two clinically available MR volumetry software, NeuroQuant® (NQ) and Inbrain® (IB), and examine the inter-method reliabilities and differences between them. Materials and Methods: This study included 172 subjects...
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Comparison of Vendor-Provided Volumetry Software and NeuroQuant Using 3D T1-Weighted Images in Subjects with Cognitive Impairment: How Large is the Inter-Method Discrepancy?

Chung J, Kim H, Moon Y, Moon WJ

Background: Determination of inter-method differences between clinically available volumetry methods are essential for the clinical application of brain volumetry in a wider context. Purpose: The purpose of this study was to...
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Alzheimer Dementia and Microvascular Pathology: Blood-Brain Barrier Permeability Imaging

Moon WJ

Accumulating evidence suggests that Alzheimer’s disease (AD) is not only caused by accumulation of abnormal proteins, including amyloid and tau, but is also closely associated with abnormalities in the microvascular...
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Concordance of Three International Guidelines for Thyroid Nodules Classified by Ultrasonography and Diagnostic Performance of Biopsy Criteria

Yim Y, Na DG, Ha EJ, Baek JH, Sung JY, Kim JH, Moon WJ

OBJECTIVE: To investigate the concordance of three international guidelines: the Korean Thyroid Association/Korean Society of Thyroid Radiology, American Thyroid Association, and American College of Radiology for thyroid nodules classified by...
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Altered Functional Brain Networks in Patients with Traumatic Anosmia: Resting-State Functional MRI Based on Graph Theoretical Analysis

Park M, Chung J, Kim JK, Jeong Y, Moon WJ

OBJECTIVE: Traumatic anosmia is a common disorder following head injury; however, little is known regarding its neural basis and influence on the functional networks. Therefore, we aimed to investigate the...
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Korean Clinical Imaging Guidelines for Diagnosis of Headache Based on the 2017 Evidence-Based Clinical Imaging Guidelines

Jung JS, Oh SW, Jang J, Choi CH, Kim SC, Moon WJ, Choi M, Jung SE

Headache is the most common cause of neurological disorders. The usefulness of imaging tests may vary depending on the patient's clinical situation. The Korean Society of Radiology and National Evidence-Based...
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Gadolinium Deposition in the Brain: Current Updates

Choi JW, Moon WJ

Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR imaging and have long been considered safe when administered at recommended doses. However, since the report that nephrogenic systemic...
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Dynamic Susceptibility Contrast (DSC) Perfusion MR in the Prediction of Long-Term Survival of Glioblastomas (GBM): Correlation with MGMT Promoter Methylation and 1p/19q Deletions

Kwon YW, Moon WJ, Park M, Roh HG, Koh YC, Song SW, Choi JW

PURPOSE: To investigate the surgical, perfusion, and molecular characteristics of glioblastomas which influence long-term survival after treatment, and to explore the association between MR perfusion parameters and the presence of...
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Inter-Vendor and Inter-Session Reliability of Diffusion Tensor Imaging: Implications for Multicenter Clinical Imaging Studies

Min J, Park M, Choi JW, Jahng GH, Moon WJ

OBJECTIVE: To evaluate the inter-vendor and inter-session reliability of diffusion tensor imaging (DTI) and relevant parameters. MATERIALS AND METHODS: This prospective study included 10 healthy subjects (5 women and 5 men;...
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Functional Magnetic Resonance Imaging to Evaluate Patient Satisfaction Following Bimaxillary Surgery: A Preliminary Study

Kim JS, Park M, Hwang MJ, Moon WJ

Although bimaxillary surgery enhances patients' self-esteem and mood by improving their facial appearance, surgical outcome assessments for this procedure are limited. This preliminary study investigated differences in brain activity on...
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Structural MR Imaging in the Diagnosis of Alzheimer's Disease and Other Neurodegenerative Dementia: Current Imaging Approach and Future Perspectives

Park M, Moon WJ

With the rise of aging population, clinical concern and research attention has shifted towards neuroimaging of dementia. The advent of 3T, magnetic resonance imaging (MRI) has permitted the anatomical imaging...
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A Multicenter Prospective Validation Study for the Korean Thyroid Imaging Reporting and Data System in Patients with Thyroid Nodules

Ha EJ, Moon WJ, Na DG, Lee YH, Choi N, Kim SJ, Kim JK

OBJECTIVE: To validate a new risk stratification system for thyroid nodules, the Korean Thyroid Imaging Reporting and Data System (K-TIRADS), using a prospective design. MATERIALS AND METHODS: From June 2013 to...
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