J Korean Neurol Assoc.  2015 May;33(2):103-105. 10.17340/jkna.2015.2.6.

Cortical Hypometabolism in Opsoclonus-Myoclonus Syndrome

Affiliations
  • 1Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. lyoochel@yuhs.ac

Abstract

Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic myoclonic jerks predominantly involving the trunk, limbs, and head. We present two patients with OMS after respiratory tract infection who exhibited diffuse cerebral hypometabolism, particularly in the parieto-occipital cortex on 18F-fluorodeoxyglucose positron-emission tomography (F-FDG PET). This metabolic change might be a consequence rather than a direct cause of motor symptoms, which may be attributable to brainstem or cerebellar pathology.

Keyword

Opsoclonus-myoclonus syndrome; 18F-FDG PET

MeSH Terms

Brain Stem
Extremities
Head
Humans
Myoclonus
Ocular Motility Disorders
Opsoclonus-Myoclonus Syndrome*
Pathology
Positron-Emission Tomography
Respiratory Tract Infections
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