J Korean Child Neurol Soc.  2005 May;13(1):1-7.

Epilepsy, Reactive Oxygen Species and Mitochondria

• Kim WS

Abstract

Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, reactive oxygen species play an important role in seizure initiation and seizure-induced brain damage. In mitochondrial diseases, epileptic seizures are also noted from defects of oxidative phosphorylation. So oxidative stress from reactive oxygen species is important in mitochondrial dysfunction and epileptic seizure.

Keyword

Epilepsy; Reactive oxygen species; Mitochondria

MeSH Terms

Brain
Epilepsy*
Mitochondria*
Mitochondrial Diseases
Nervous System Diseases
Oxidative Phosphorylation
Oxidative Stress
Reactive Oxygen Species*
Seizures
Reactive Oxygen Species