Tuberc Respir Dis.  2001 Oct;51(4):390-394. 10.4046/trd.2001.51.4.390.

A Case of Lymphocytic Interstitial Pneumonia

• Suh YA
• Kim SI
• Kim DH
• Kwak JY
• Lee JC
• Baek HJ
• Chung JH

• KMID: 2160028
• DOI: http://doi.org/10.4046/trd.2001.51.4.390

Abstract

Lymphocytic interstitial pneumonia(LIP) is characterized by a massive infiltration of the interstitium of the lung by mature lymphocytes, plasma cells and reticuloendothelial cells. LIP may be associated with autoimmune diseases including Sjogrens syndrome, SLE, myasthenia gravis, pernicious anemia, autoimmune hemolytic anemia, and HIV or an EB virus infection. There is a possibility of LIP progressing to a pulmonary or systemic lymphoma. The therapeutic response to corticosteroids and/or immunosuppressive drugs varies. Here we report a case of LIP that was diagnosed by an open lung biopsy and clonality study. The patient was a 36 year-old man without antuimmune disease or HIV infection. He was admitted as a result of severe hypoxemia showing PaO2 of 48.3 mmHg. The patient was treated with corticosteroids after the diagnosis and had fully recovered without a sequalae or relapse.

Keyword

Lymphocytic interstitial pneumonia

MeSH Terms

Adrenal Cortex Hormones
Anemia, Hemolytic, Autoimmune
Anemia, Pernicious
Anoxia
Autoimmune Diseases
Biopsy
Diagnosis
HIV
HIV Infections
Humans
Lip
Lung
Lung Diseases, Interstitial*
Lymphocytes
Lymphoma
Myasthenia Gravis
Plasma Cells
Recurrence
Sjogren's Syndrome
Adrenal Cortex Hormones