- Laboratory Monitoring of Biological Therapies in Rheumatology: The Role of Immunogenicity
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Benucci M, Grossi V, Manfredi M, Damiani A, Infantino , Moscato P, Cinquanta , Gremese E, Tolusso B, Petricca L, Fedele AL, Alivernini S, Atzeni F, Minisola G, Verna R
- KMID: 2460907
- Ann Lab Med.
- 2020 Mar;40(2):101-113.
- doi: 10.3343/alm.2020.40.2.101
Biological drugs, such as proteins and immunogens, are increasingly used to treat various diseases, including tumors and autoimmune diseases, and biological molecules have almost completely replaced synthetic drugs in rheumatology.... -
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- Clinical Characteristics and Treatment of Immune-Related Adverse Events of Immune Checkpoint Inhibitors
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Choi J, Lee SY
- KMID: 2471049
- Immune Netw.
- 2020 Feb;20(1):e9.
- doi: 10.4110/in.2020.20.e9
Immune checkpoint inhibitors (ICIs) have been changing the paradigm of cancer treatment. However, immune-related adverse effects (irAEs) have also increased with the exponential increase in the use of ICIs. ICIs... -
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- Regulatory T Cells in Tumor Microenvironment and Approach for Anticancer Immunotherapy
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Kim JH, Kim BS, Lee SK
- KMID: 2471044
- Immune Netw.
- 2020 Feb;20(1):e4.
- doi: 10.4110/in.2020.20.e4
Tregs have a role in immunological tolerance and immune homeostasis by suppressing immune reactions, and its therapeutic potential is critical in autoimmune diseases and cancers. There have been multiple studies... -
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- Diffuse Systemic Sclerosis in a Patient with Primary Biliary Cirrhosis and Autoimmune Hepatitis Overlap Syndrome: A Case Report
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Han HS, Ahn GR, Kim HJ, Park KY, Li K, Seo SJ
- KMID: 2467204
- Ann Dermatol.
- 2020 Feb;32(1):69-73.
- doi: 10.5021/ad.2020.32.1.69
Systemic sclerosis (SSc) is a chronic systemic disease of unknown etiology characterized by vasculopathy, excessive accumulation of extracellular matrix, and fibrosis of the skin and other internal organs. Although its... -
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- Rifampin-Induced Immune Hemolytic Anemia during Treatment of Pulmonary Tuberculosis in a Patient with Primary Sjogren's Syndrome
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Souk JW, Kim YK, Jang GE, Jeong HS, Uh ST, Kim KU, Koo SM, Lee BY, Noh H, Shin WY, Shin JW, Jin SY
- KMID: 2470584
- Korean J Blood Transfus.
- 2019 Dec;30(3):246-252.
- doi: 10.17945/kjbt.2019.30.3.246
Drug-induced immune hemolytic anemia is a rare disease that occurs in 1 in 1 million individuals of the general population. Rifampin-induced immune hemolytic anemia is caused by drug-dependent antibodies and... -
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- Recurrent Optic Neuritis and Acute Encephalopathy with Myelin Oligodendrocyte Glycoprotein Antibodies in a Korean Child
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Hwang JE, Kim SH, Park S
- KMID: 2470412
- Soonchunhyang Med Sci.
- 2019 Dec;25(2):121-124.
- doi: 10.0000/sms.2019.25.2.121
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases are reported to have distinct pathogenic mechanisms, clinical courses, and therapeutic implications in comparison to other acquired demyelinating syndromes. Here, we report the case... -
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- A novel compound heterozygous mutation of the AIRE gene in a patient with autoimmune polyendocrine syndrome type 1
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Suh J, Choi HS, Kwon A, Chae HW, Lee JS, Kim HS
- KMID: 2468727
- Ann Pediatr Endocrinol Metab.
- 2019 Dec;24(4):248-252.
- doi: 10.6065/apem.2019.24.4.248
Autoimmune polyendocrine syndrome type 1 (APS-1), or autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is a rare, autosomal recessive autoimmune disease caused by a mutation of the autoimmune regulator (AIRE) gene. The main symptom... -
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- Autoantibody-Mediated Dysfunction of Salivary Glands Leads to Xerostomia in SKG Mice
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Choi SS, Jang E, Jang K, Jung SJ, Hwang KG, Youn J
- KMID: 2466614
- Immune Netw.
- 2019 Dec;19(6):e44.
- doi: 10.4110/in.2019.19.e44
Sjögren's syndrome (SS) is a chronic heterogeneous disease that mainly affects exocrine glands, leading to sicca syndromes such as xerostomia. Despite the second highest prevalence rate among systemic autoimmune diseases,... -
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- Treatment of Graves' Ophthalmopathy
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Lee JK
- KMID: 2465061
- Int J Thyroidol.
- 2019 Nov;12(2):91-96.
- doi: 10.11106/ijt.2019.12.2.91
Graves' ophthalmopathy (GO) is an autoimmune disease associated with orbital inflammation and fibrosis which can result in lid retraction, soft tissue swelling, and proptosis. Treatment should rely on a thorough... -
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- Systemic Sclerosis and Microbiota: Overview of Current Research Trends and Future Perspective
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Kim S, Chun SH, Park HJ, Lee SI
- KMID: 2459448
- J Rheum Dis.
- 2019 Oct;26(4):235-247.
- doi: 10.4078/jrd.2019.26.4.235
The commensal microbiota contributes to the maintenance of immune homeostasis in the human body. Autoimmunity can be aggravated or alleviated by the microbiota, which affects both innate and adaptive immune... -
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- Diagnostic Challenge: Primary Bone Marrow Diffuse Large B-cell Lymphoma Mimicking Systemic Autoimmune Diseases
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Oh J, Kim Y, Lee ST, Lee KA
- KMID: 2458685
- Lab Med Online.
- 2019 Oct;9(4):242-245.
- doi: 10.3343/lmo.2019.9.4.242
No abstract available. -
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- Diagnosis of Systemic Scleroderma in a Patient with Leg Ulcer
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Ju GS, Son KM, Choi WY, Cheon JS
- KMID: 2465856
- J Wound Manag Res.
- 2019 Sep;15(2):121-124.
- doi: 10.22467/jwmr.2019.00759
Systemic scleroderma is an autoimmune disease that affects connective tissue in internal organs and the skin with thickening and fibrosis. When afflicting internal organs, the disease leads to reduced quality... -
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- Stiff-Person Syndrome: Diagnostic Difficulty
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Lee JK, Kang C, Kim SB, An BK, Lee GS
- KMID: 2458015
- J Korean Foot Ankle Soc.
- 2019 Sep;23(3):131-134.
- doi: 10.14193/jkfas.2019.23.3.131
Stiff-person syndrome is a rare disorder, and the natural history of the syndrome has not been completely ascertained. The symptoms range from mild to severe and can progress over time:... -
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- Urticaria: Classification and Diagnosis
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Ye YM
- KMID: 2454678
- Korean J Med.
- 2019 Aug;94(4):353-357.
- doi: 10.3904/kjm.2019.94.4.353
Urticaria is a common cutaneous disease characterized by recurrent and transient wheals and pruritus, sometimes accompanied angioedema. The classification of urticaria is based on the duration of the disease and... -
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- Treatment of Hidradenitis Suppurativa Patient with Klinefelter Syndrome by Adalimumab
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Shin JY, Hong JY, Lee HJ, Sim CY, Park YL, Lee JS, Lee SY, Kim JE
- KMID: 2451484
- Ann Dermatol.
- 2019 Aug;31(4):446-449.
- doi: 10.5021/ad.2019.31.4.446
Hidradenitis suppurativa (HS) is a chronic, inflammatory and painful skin disease with recurrent nodules and tracts involving the intertriginous regions. It is known that the patient with HS shows an... -
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- Clinical Relevance for Serum Cold-Inducible RNA-Binding Protein Level in Alopecia Areata
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Shin JM, Ko JW, Kwon IS, Choi JW, Hong D, Lee JH, Seo YJ, Kim CD, Lee JH, Lee Y, Park KD
- KMID: 2451475
- Ann Dermatol.
- 2019 Aug;31(4):387-392.
- doi: 10.5021/ad.2019.31.4.387
BACKGROUND: Alopecia areata (AA), a chronic, relapsing hair-loss disorder, is considered to be a T-cell-mediated autoimmune disease. Cold-inducible RNA-binding protein (CIRP) belongs to a family of cold-shock proteins that respond... -
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- A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells
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Yi TG, Cho YK, Lee HJ, Kim J, Jeon MS, Ham DS, Kim WC, Song SU
- KMID: 2465901
- Int J Stem Cells.
- 2019 Jul;12(2):315-330.
- doi: 10.15283/ijsc18098
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation. METHODS AND RESULTS:... -
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- The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus
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Men K, Chen Y, Zhang J, Wei D
- KMID: 2457324
- Korean J Intern Med.
- 2019 Jul;34(4):932-937.
- doi: 10.3904/kjim.2017.224
BACKGROUND/AIMS: To evaluate cellular immune function in systemic lupus erythematosus (SLE) patients over 60 years old, the association between antinuclear antibody (ANA) titers and the ratio of CD4âº/CD8⺠was analyzed... -
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- Systematic Review on Sanitary Pads and Female Health
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Woo J, Kim S, Kim H, Jeong KS, Kim E, Ha E
- KMID: 2454663
- Ewha Med J.
- 2019 Jul;42(3):25-38.
- doi: 10.12771/emj.2019.42.3.25
The majority of South Korean females use sanitary pads, which contain various organic solvents which could be excreted before and during their menstruation. However, they are not provided with findings... -
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- Autoimmune Diseases and Gastric Cancer Risk: A Systematic Review and Meta-Analysis
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Song M, Latorre G, Ivanovic-Zuvic D, Camargo MC, Rabkin CS
- KMID: 2454277
- Cancer Res Treat.
- 2019 Jul;51(3):841-850.
- doi: 10.4143/crt.2019.151
PURPOSE: Autoimmunity is an alternative etiology of gastric inflammation, the initiating event in the gastric carcinogenic cascade. This mechanism may be an increasingly important cause of gastric cancer with the... -
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