J Korean Med Sci.  1998 Feb;13(1):85-88. 10.3346/jkms.1998.13.1.85.

A case of autoimmune cholangitis associated with Sjogren's syndrome and arthropathy

• Lee J
• Chang KH
• Park CS
• Lee CH
• Song CH
• Park YN
• Park C
• Lee SK

• KMID: 1107233
• DOI: http://doi.org/10.3346/jkms.1998.13.1.85

Abstract

Autoimmune cholangitis (AC) is a recently proposed entity that describes a specific group of patients presenting overlapping features of primary biliary cirrhosis (PBC) and autoimmune hepatitis. The disease is characterized by dinical cholestasis, high titer antinuclear antibody, negative antimitochondrial antibody, and histologically, findings of PBC coexisting with varying degrees of parenchymal inflammation. In this report, we describe a patient with Sjogren's syndrome who fulfilled the diagnostic criteria of AC associated with unique arthropathy compatible with arthritis of PBC. This case illustrates the unusual coexistence of two diseases that may share similar pathogenic processes.

MeSH Terms

Autoimmune Diseases/therapy
Autoimmune Diseases/physiopathology
Autoimmune Diseases/pathology
Autoimmune Diseases/complications*
Case Report
Cholangitis/therapy
Cholangitis/physiopathology
Cholangitis/pathology
Cholangitis/complications*
Female
Human
Middle Age
Sjogren's Syndrome/physiopathology
Sjogren's Syndrome/pathology
Sjogren's Syndrome/complications*