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The Efficacy of Topical Tacrolimus Ointment on Cheilitis Induced by Isotretinoin Treatment in Acne Vulgaris Patients

Song CH, Jung YJ, Shin DS, Kim KY, Kim JE, Ko JY, Ro YS

  • KMID: 2518990
  • Korean J Dermatol.
  • 2021 Jul;59(6):468-473.
Background: Isotretinoin is a gold standard treatment for moderate to severe acne vulgaris but is associated with cheilitis. Though moisturizing agents or petrolatum have been suggested, uncomfortable isotretinoin-induced cheilitis can...
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Anti-allergic Effect of Fructus amomi on Ovalbumin-induced Asthma Mice Model

Piao CH, Fan YJ, Nguyen TV, Yu ZN, Shin HS, Song CH, Chai OH

Despite studies on the anti-inflammatory effect of Fructus amomi, mature fruit of Amomum villosum Lour, have been getting increasing extensively, it remains unknown about the detailed effects of F. amomi...
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Imatinib Mesylate-Induced Acquired Dermal Melanocytosis and Acquired Bilateral Nevus of Ota-Like Macules

Jang JW, Song CH, Jung YJ, Cheon DU, Koh WS, Ro YS, Ko JY

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Regression of Congenital Melanocytic Nevus with Halo Phenomenon Induced by Serial Excision

Song CH, Jung YJ, Ko YW, Kim JE, Ko JY, Ro YS

  • KMID: 2516147
  • Korean J Dermatol.
  • 2021 May;59(4):310-313.
Congenital melanocytic nevus is a hamartoma derived from the neural crest that is present at birth. Regression following surgical excision with an apparent halo phenomenon through suture lines has never...
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Nuclear Factor Erythroid 2-related Factor 2 Knockout Suppresses the Development of Aggressive Colorectal Cancer Formation Induced by Azoxymethane/Dextran Sulfate Sodium-Treatment in Female Mice

Song CH, Kim N, Nam RH, Choi SI, Kang C, Jang JY, Nho H, Shin E, Lee HN

Colon tumors develop more frequently in male than in female. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays differential roles in the stage of tumorigenesis. The purpose of this study...
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Changes in Cecal Microbiota and Short-chain Fatty Acid During Lifespan of the Rat

Choi SI, Son JH, Kim N, Kim YS, Nam RH, Park JH, Song CH, Yu JE, Lee DH, Yoon K, Min H, Kim YR, Seok YJ

  • KMID: 2510071
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):134-146.
  • doi: 10.5056/jnm20148
Background/Aims The gut microbiota regulates intestinal immune homeostasis through host-microbiota interactions. Multiple factors affect the gut microbiota, including age, sex, diet, and use of drugs. In addition, information on gut microbiota...
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A Case of Simultaneous Development of Multiple Bowen’s Disease and Basal Cell Carcinoma in a Young Patient Associated with Arsenic Exposure

Song CH, Jung YJ, Ko YW, Kim JE, Ko JY, Ro YS

  • KMID: 2506596
  • Korean J Dermatol.
  • 2020 Sep;58(8):572-574.
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Anti-allergic Effects of Caffeine in an Allergic Rhinitis Mouse Model

Fan YJ, Piao CH, Nguyen TV, Yu ZN, Chai OH, Song CH

Caffeine (1, 3, 7-trimethylxanthine) is one of the most widely consumed pharmacologically active products worldwide. Caffeine exhibits various pharmacological activities in central nervous, cardiovascular, and respiratory systems. Additionally, caffeine exhibited...
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17β-Estradiol reduces inflammation and modulates antioxidant enzymes in colonic epithelial cells

Son HJ, Kim N, Song CH, Lee SM, Lee HN, Surh YJ

Background/Aims: Estrogen is known to have protective effect in colorectal cancer development. The aims of this study are to investigate whether estradiol treatment reduces inflammation in CCD841CoN, a female human...
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A Case of Livedoid Vasculopathy Successfully Treated with Sulodexide

Song CH, Shin DS, Jang JW, Kim TL, Kim YG, Kim JS, Seo HM

We report a 29-year-old female with a one-month history of non-healing multiple erythematous to violaceous plaques with crusts over both legs and feet. Tender, scarring ulcers with surrounding erythema were...
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Expression of Neurotrophic Factors, Tight Junction Proteins, and Cytokines According to the Irritable Bowel Syndrome Subtype and Sex

Lee JY, Kim N, Park JH, Nam RH, Lee SM, Song CH, Kim G, Na HY, Choi YJ, Kim JJ, Lee DH

  • KMID: 2500655
  • J Neurogastroenterol Motil.
  • 2020 Jan;26(1):106-116.
  • doi: 10.5056/jnm19099
Background/Aims Emerging evidence shows that the mechanism of irritable bowel syndrome (IBS) is associated with neurotrophic factors and tight junction proteins (TJPs). It is known that there are sex differences...
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Sex-related Alterations of Gut Microbiota in the C57BL/6 Mouse Model of Inflammatory Bowel Disease

Son HJ, Kim N, Song CH, Nam RH, Choi SI, Kim JS, Lee DH

BACKGROUND: Gut microbiota is closely associated with development and exacerbation of inflammatory bowel diseases (IBD). The aim of this study was to investigate differences in gut microbiota depending on sex...
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Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development

Son HJ, Sohn SH, Kim N, Lee HN, Lee SM, Nam RH, Park JH, Song CH, Shin E, Na HY, Kim JS, Lee DH, Surh YJ

PURPOSE: This study demonstrates that estradiol downregulates inflammation and inhibits colorectal cancer (CRC) development in azoxymethane/dextran sulfate sodium (AOM/DSS) mouse model. MATERIALS AND METHODS: AOM/DSS-treated male and female mice were sacrificed...
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Implant-Supported Fixed Dental Prostheses with New Retention Type Using Zirconia Ball and Nickel-Titanium Spring

Choi JW, Song CH, Huh JB

EZ Crown system (EZC), a new retention type implant prosthetic system that has not only easy retrievability but also no complication due to residual cement, was developed to overcome the...
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Rat Intestinal Acetic Acid and Butyric acid and Effects of Age, Sex, and High-fat Diet on the Intestinal Levels in Rats

Choi SI, Kim N, Lee SM, Nam RH, Kang SR, Song CH, Park YT, Min H, Kim YR, Seok YJ

BACKGROUND: High-fat diet is known to be implicated in the pathogenesis of various metabolic disorders related to an inflammatory response. The aim of this study was to investigate the influence...
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Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model

Song CH, Kim N, Sohn SH, Lee SM, Nam RH, Na HY, Lee DH, Surh YJ

BACKGROUND/AIMS: Intestinal barrier dysfunction is a hallmark of inflammatory bowel diseases (IBDs) such as ulcerative colitis. This dysfunction is caused by increased permeability and the loss of tight junctions in...
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Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation and mast cell-mediated anaphylactic shock by regulation of Th1/Th2 imbalance and histamine release

Bui TT, Piao CH, Song CH, Lee CH, Shin HS, Chai OH

Asthma is characterized by chronic inflammation, goblet cell hyperplasia, the aberrant production of the Th2 cytokines, and eosinophil infiltration into the lungs. In this study, we examined the effects of...
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Innate Lymphoid Cells and Infection

Song CH

The functions of innate lymphoid cells (ILCs) have been known to play an important role in immunity and immune responses. ILCs are rapidly-responding cells that are involved in tissue remodeling,...
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Morphometric Study of Cricoid Cartilage in Korean

Kim IS, Song CH

This study is aimed to measure the morphology of Korean cricoid cartilages. A total of 48 - 33 males and 15 females - cadavers were used in this study. When...
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The Morphometric Study of Main Bronchus in Korean Cadaver

Kim IS, Song CH

This morphometric study of main bronchus was performed to provide the basic data necessary for anatomists, anesthetists and emergency medical technicians. A total of 48 cadavers, 33 men and 15...
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