- The Influence of Bcl-3 Expression on Cell Migration and Chemosensitivity of Gastric Cancer Cells via Regulating Hypoxia-Induced Protective Autophagy
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Hu L, Bai Z, Ma X, Bai N, Zhang Z
- KMID: 2471929
- J Gastric Cancer.
- 2020 Mar;20(1):95-105.
- doi: 10.5230/jgc.2020.20.e9
PURPOSE: Gastric cancer is a highly metastatic malignant tumor, often characterized by chemoresistance and high mortality. In the present study, we aimed to investigate the role of B-cell lymphoma 3... -
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- Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections
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Lee JH, Yim HE, Yoo KH
- KMID: 2471799
- J Korean Med Sci.
- 2020 Mar;35(10):e65.
- doi: 10.3346/jkms.2020.35.e65
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children... -
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- The optimal model of reperfusion injury in vitro using H9c2 transformed cardiac myoblasts
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Son E, Lee D, Woo CW, Kim YH
- KMID: 2471039
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):173-183.
- doi: 10.4196/kjpp.2020.24.2.173
An in vitro model for ischemia/reperfusion injury has not been well-established. We hypothesized that this failure may be caused by serum deprivation, the use of glutamine-containing media, and absence of... -
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- Case Series of Transfusion-Related Acute Lung Injury in a Tertiary Hospital and a Practical Comparison with the New Diagnostic Criteria
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Lee KS, Kim S, Roh J, Choi SJ, Kim HO
- KMID: 2470580
- Korean J Blood Transfus.
- 2019 Dec;30(3):219-229.
- doi: 10.17945/kjbt.2019.30.3.219
BACKGROUND: Transfusion-related acute lung injury (TRALI) is defined as acute respiratory distress syndrome with non-cardiogenic pulmonary edema caused by transfusion. It occurs only rarely but could result in patient mortality.... -
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- The role of oxidative stress and hypoxia in renal disease
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Honda T, Hirakawa Y, Nangaku M
- KMID: 2469372
- Kidney Res Clin Pract.
- 2019 Dec;38(4):414-426.
- doi: 10.23876/j.krcp.19.063
Oxygen is required to sustain aerobic organisms. Reactive oxygen species (ROS) are constantly released during mitochondrial oxygen consumption for energy production. Any imbalance between ROS production and its scavenger system... -
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- Organ donation in Korea in 2018 and an introduction of the Korea national organ donation system
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Cho WH
- KMID: 2468158
- Korean J Transplant.
- 2019 Dec;33(4):83-97.
- doi: 10.4285/jkstn.2019.33.4.83
A total of 1,503 solid organs were procured from 449 deceased donors in 2018. Although the number of donors was down by 12.8% from the previous year (8.7 per million... -
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- Genipin Inhibits Hypoxia-Induced Accumulation of HIF-1α and VEGF Expressions in Human Cervical Carcinoma Cells
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Jin CE, Lee JH, Kim GJ, Lee TH
- KMID: 2467971
- Kosin Med J.
- 2019 Dec;34(2):106-116.
- doi: 10.7180/kmj.2019.34.2.106
OBJECTIVES: Hypoxia—a characteristic of almost all types of solid tumors—has been associated with poor outcomes in several human malignancies. Genipin—an active constituent of Gardenia fruit— has been reported to exert... -
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- Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes
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Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB
- KMID: 2467051
- Tissue Eng Regen Med.
- 2019 Dec;16(6):585-593.
- doi: 10.1007/s13770-019-00215-w
BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major... -
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- Neuregulin 1/ErbB4 signaling attenuates neuronal cell damage under oxygen-glucose deprivation in primary hippocampal neurons
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Yoo JY, Kim HB, Yoo SY, Yoo HI, Song DY, Baik TK, Lee JH, Woo RS
- KMID: 2466700
- Anat Cell Biol.
- 2019 Dec;52(4):462-468.
- doi: 10.5115/acb.19.210
The hippocampus is one of the most important brain areas of cognition. This region is particularly sensitive to hypoxia and ischemia. Neuregulin-1 (NRG1) has been shown to be able to... -
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- High-flow nasal oxygenation for anesthetic management
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Kim HJ, Asai T
- KMID: 2465723
- Korean J Anesthesiol.
- 2019 Dec;72(6):527-547.
- doi: 10.4097/kja.19174
High-flow nasal oxygenation (HFNO) is a promising new technique for anesthesiologists. The use of HFNO during the induction of anesthesia and during upper airway surgeries has been initiated, and its... -
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- Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation
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Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L
- KMID: 2463799
- Yonsei Med J.
- 2019 Dec;60(12):1195-1202.
- doi: 10.3349/ymj.2019.60.12.1195
PURPOSE: The aim of this study was to investigate whether propofol could attenuate hypoxia/reoxygenation-induced apoptosis and autophagy in human renal proximal tubular cells (HK-2) by inhibiting JNK activation. MATERIALS AND METHODS:... -
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- Neuregulin-1 Protects Neuronal Cells Against Damage due to CoCl2-Induced Hypoxia by Suppressing Hypoxia-Inducible Factor-1α and P53 in SH-SY5Y Cells
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Yoo SY, Yoo JY, Kim HB, Baik TK, Lee JH, Woo RS
- KMID: 2467319
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S111-S118.
- doi: 10.5213/inj.1938190.095
PURPOSE: Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present... -
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- Effect of a rapid response system on code rates and in-hospital mortality in medical wards
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Lee HY, Lee J, Lee SM, Kim S, Yang E, Lee HJ, Lee H, Ryu HG, Oh SY, Ha EJ, Ko SB, Cho J
- KMID: 2467303
- Acute Crit Care.
- 2019 Nov;34(4):246-254.
- doi: 10.4266/acc.2019.00668
BACKGROUND: To determine the effects of implementing a rapid response system (RRS) on code rates and in-hospital mortality in medical wards. METHODS: This retrospective study included adult patients admitted to medical... -
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- Sudden Unexpected Death During Bronchoscopy of a Patient with Pulmonary Lymphangitic Carcinomatosis and Pulmonary Tumor Thrombotic Microangiopathy due to Gastric Cancer
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Park S, Na JY, Choi BH
- KMID: 2464493
- Korean J Leg Med.
- 2019 Nov;43(4):153-158.
- doi: 10.7580/kjlm.2019.43.4.153
We present the case of a 48-year-old woman who complained of sustained dyspnea and newly developed dyspnea, who then suddenly and unexpectedly expired during bronchoscopy. On postmortem examination, the deceased... -
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- Acute respiratory distress-syndrome in the general complications of severe acute pancreatitis
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Ibadov RA, Arifjanov , Ibragimov , Abdullajanov BR
- KMID: 2464325
- Ann Hepatobiliary Pancreat Surg.
- 2019 Nov;23(4):359-364.
- doi: 10.14701/ahbps.2019.23.4.359
BACKGROUNDS/AIMS: Improvement of efficiency of treatment of patients with severe acute pancreatitis (SAP), complicated by acute respiratory distress-syndrome (ARDS). METHODS: The retrospective research of 67 SAP patients treated at the ICU... -
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- Whole body ultrasound in the operating room and intensive care unit
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Denault A, Canty D, Azzam M, Amir A, Gebhard CE
- KMID: 2465741
- Korean J Anesthesiol.
- 2019 Oct;72(5):413-428.
- doi: 10.4097/kja.19186
Whole body ultrasound can be used to improve the speed and accuracy of evaluation of an increasing number of organ systems in the critically ill. Cardiac and abdominal ultrasound can... -
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- Adverse events of conscious sedation using midazolam for gastrointestinal endoscopy
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Jun J, Han JI, Choi AL, Kim YJ, Lee JW, Kim DY, Lee M
- KMID: 2465336
- Anesth Pain Med.
- 2019 Oct;14(4):401-406.
- doi: 10.17085/apm.2019.14.4.401
BACKGROUND: This study was conducted to identify the types and incidence of adverse events associated with midazolam, which is the most widely used drug to induce conscious sedation during gastrointestinal... -
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- Low-Frequency Intermittent Hypoxia Suppresses Subcutaneous Adipogenesis and Induces Macrophage Polarization in Lean Mice
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Wang Y, Lee MY, Mak JC, Ip MS
- KMID: 2460959
- Diabetes Metab J.
- 2019 Oct;43(5):659-674.
- doi: 10.4093/dmj.2018.0196
BACKGROUND: The relationship between obstructive sleep apnoea (OSA) and metabolic disorders is complex and highly associated. The impairment of adipogenic capacity in pre-adipocytes may promote adipocyte hypertrophy and increase the... -
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- Analysis of factors involved in brain-death donor processing for face transplantation in Korea: How much time is available from brain death to transplantation?
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Hong JW, Chung SW, Ahn SJ, Lee WJ, Lew DH, Kim YO
- KMID: 2464615
- Arch Plast Surg.
- 2019 Sep;46(5):405-413.
- doi: 10.5999/aps.2019.00150
BACKGROUND: Face transplantation has naturally evolved from reconstructive procedures. However, few institutions perform face transplantations, because it is time-consuming and it is necessary to justify non-vital organ transplantation. We investigated... -
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- SYM 2081 Exerts Neuroprotective Effect Modulating Anti-Apoptosis in the Hypoxic-Ischemic Brain Injury of Neonatal Rats
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Park JK, Jang YY, Jeong JE, Lee EJ, Choi EJ, Chung HL, Kim WT
- KMID: 2460024
- Perinatology.
- 2019 Sep;30(3):117-125.
- doi: 10.14734/PN.2019.30.3.117
OBJECTIVE: SYM 2081 ((2S,4R)-4-methylglutamic acid), an agonist and functional antagonist of the kainite receptor, has shown a neuroprotective effect in neurodegenerative diseases in adults but little is known concerning perinatal... -
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