Tuberc Respir Dis.  2001 Jul;51(1):59-64. 10.4046/trd.2001.51.1.59.

A Case of Nonspecific Interstitial Pneumonia with Clinical Course of Rapid Aggravation

• Yoo BH
• Suhr JW
• Yoon HJ
• Baek JT
• Lee SH
• Paik CN
• Lee JE
• Kim SJ
• Park SH
• Lee EH

• KMID: 2318338
• DOI: http://doi.org/10.4046/trd.2001.51.1.59

Abstract

Nonspecific interstitial pneumonia (NSIP) was first described as a new category of idiopathic interstitial pneumonia in 1994. This is a disease with a more insidious onset and has a chronic course. The histological findings are unusual for other idiopathic interstitial pneumonia cases (usual interstitial pneumonia, diffuse interstitial pneumonia, and acute interstitial pneumonia). In contrast to NSIP, acute interstitial pneumonia (AIP) has an acute onset and a fulminant course with the rapid development of respiratory failure. A pathological examination demonstrated characteristic diffuse interstitial fibrosis, hyaline membranes, thrombi, and architectural derangement. Here we report a 48-year-old woman who was diagnosed pathologically NSIP, but with a rapid progressive course similar to AIP.

Keyword

Non Specific Interstitial Pneumonia (NSIP); Acute Interstitial Pneumonia (AIP); Idiopathic Pulmonary Fibrosis (IPF)

MeSH Terms

Female
Fibrosis
Humans
Hyalin
Idiopathic Interstitial Pneumonias
Lung Diseases, Interstitial*
Membranes
Middle Aged
Respiratory Insufficiency