- Current Diagnosis and Management of Hypersensitivity Pneumonitis
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Leone PM, Richeldi L
- KMID: 2471888
- Tuberc Respir Dis.
- 2020 Apr;83(2):122-131.
- doi: 10.4046/trd.2020.0012
Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial... -
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- Recent Advances in Molecular Basis of Lung Aging and Its Associated Diseases
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Kang MJ
- KMID: 2471886
- Tuberc Respir Dis.
- 2020 Apr;83(2):107-115.
- doi: 10.4046/trd.2020.0003
Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying... -
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- Two Cases of Aquagenic Wrinkling of the Palms in Korean Healthy Women: Easily Overlooked Disease
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Choi H, Bae IH, Kim MS, Na CH, Shin BS
- KMID: 2471342
- Ann Dermatol.
- 2020 Apr;32(2):151-154.
- doi: 10.5021/ad.2020.32.2.151
Aquagenic wrinkling of the palms (AWP) is a rare condition, which is characterized by appearance of whitish papules and plaques and an excessive wrinkling and swelling of the palmar skin... -
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- Diagnosis and treatment of interstitial lung disease: focusing on idiopathic pulmonary fibrosis
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Kang HR, Choi SM
- KMID: 2471864
- J Korean Med Assoc.
- 2020 Mar;63(3):159-168.
- doi: 10.5124/jkma.2020.63.3.159
Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough... -
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- Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections
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Lee JH, Yim HE, Yoo KH
- KMID: 2471799
- J Korean Med Sci.
- 2020 Mar;35(10):e65.
- doi: 10.3346/jkms.2020.35.e65
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children... -
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- Visceral-to-Subcutaneous Abdominal Fat Ratio Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis
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Jung CH, Rhee EJ, Kwon H, Chang Y, Ryu S, Lee WY
- KMID: 2471733
- Endocrinol Metab.
- 2020 Mar;35(1):165-176.
- doi: 10.3803/EnM.2020.35.1.165
BACKGROUND: We evaluated the association of visceral-to-subcutaneous fat ratio (VSR) with nonalcoholic fatty liver disease (NAFLD) and advanced fibrosis degree based on noninvasive serum fibrosis markers in the general population... -
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- Liver Involvement in Children with Alpha-1 Antitrypsin Deficiency: A Multicenter Study
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Cakir M, Sag E, Islek A, Baran M, Tumgor G, Aydogdu S
- KMID: 2471624
- Pediatr Gastroenterol Hepatol Nutr.
- 2020 Mar;23(2):146-153.
- doi: 10.5223/pghn.2020.23.2.146
PURPOSE: Alpha-1 antitrypsin deficiency (A1ATD) in one of the most common genetic causes of liver disease in children. We aimed to analyze the clinical characteristics and outcomes of patients with... -
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- The Clinical Efficacy of Pulmonary Hypertension-Specific Agents in Idiopathic Pulmonary Fibrosis: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
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Lee J, Song JU
- KMID: 2471054
- J Korean Med Sci.
- 2020 Mar;35(8):e48.
- doi: 10.3346/jkms.2020.35.e48
BACKGROUND: Pulmonary hypertension (PH) is common in patients with idiopathic pulmonary fibrosis (IPF) and is associated with poor outcomes. This study was performed to determine the clinical efficacy of PH-specific... -
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- Comparison of Three Magnetization Transfer Ratio Parameters for Assessment of Intestinal Fibrosis in Patients with Crohn's Disease
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Meng J, Huang S, Sun C, Zhang ZW, Mao R, Yang YH, Feng ST, Li ZP, Li X
- KMID: 2470752
- Korean J Radiol.
- 2020 Mar;21(3):290-297.
- doi: 10.3348/kjr.2019.0217
OBJECTIVE: To establish a novel standardized magnetization transfer ratio (MTR) parameter which considers the element of the normal bowel wall and to compare the efficacy of the MTR, normalized MTR,... -
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- Refractory Hepatic Hydrothorax in Chronic Hepatitis C Controlled by Direct-acting Antivirals
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Kim MH, Kim DK, Eun HS, Rou WS, Kim SH, Lee BS
- KMID: 2471149
- Korean J Gastroenterol.
- 2020 Feb;75(2):98-102.
- doi: 10.4166/kjg.2020.75.2.98
Hepatic hydrothorax is a transudative pleural effusion that complicates advanced liver cirrhosis. Patients refractory to medical treatment plus salt restriction and diuretics are considered to have refractory hepatic hydrothorax and... -
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- Dietary nobiletin suppresses TGF-β1-Src-caveolin-1 dependent signaling involved with high glucose-induced renal mesangial matrix accumulation
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Kim DY, Kang YH, Kang MK
- KMID: 2471118
- J Nutr Health.
- 2020 Feb;53(1):1-12.
- doi: 10.4163/jnh.2020.53.1.1
PURPOSE: Diabetic nephropathy is one of the most important diabetic complications prompted by chronic hyperglycemia, characterized by glomerulosclerosis, tubular fibrosis, and it eventually causes kidney failure. Nobiletin is a polymethoxyflavone... -
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- Review of a novel disease entity, immunoglobulin G4-related disease
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Maehara T, Moriyama M, Nakamura S
- KMID: 2471106
- J Korean Assoc Oral Maxillofac Surg.
- 2020 Feb;46(1):3-11.
- doi: 10.5125/jkaoms.2020.46.1.3
Immunoglobulin G4 (IgG4)-related dacryoadenitis and sialoadenitis (IgG4-DS) are part of a multiorgan fibroinflammatory condition of unknown etiology termed IgG4-related disease (IgG4-RD), which has been recognized as a single diagnostic entity... -
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- Evogliptin, a Dipeptidyl Peptidase-4 Inhibitor, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice
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Kim MJ, Kim NY, Jung YA, Lee S, Jung GS, Kim JG, Lee IK, Lee S, Choi YK, Park KG
- KMID: 2470966
- Diabetes Metab J.
- 2020 Feb;44(1):186-192.
- doi: 10.4093/dmj.2018.0271
Renal fibrosis is considered to be the final common outcome of chronic kidney disease. Dipeptidyl peptidase-4 (DPP-4) inhibitors have demonstrated protective effects against diabetic kidney disease. However, the anti-fibrotic effect... -
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- Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT
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Lin S, Yu L, Ni Y, He L, Weng X, Lu X, Zhang C
- KMID: 2470964
- Diabetes Metab J.
- 2020 Feb;44(1):158-172.
- doi: 10.4093/dmj.2018.0235
BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated... -
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- NOTCH1 Pathway is Involved in Polyhexamethylene Guanidine-Induced Humidifier Disinfectant Lung Injuries
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Lee E, Kang MJ, Kim JH, Lee SH, Lee SY, Cho HJ, Yoon J, Jung S, Park Y, Oh DK, Hong SB, Hong SJ
- KMID: 2468494
- Yonsei Med J.
- 2020 Feb;61(2):186-191.
- doi: 10.3349/ymj.2020.61.2.186
An outbreak of fatal humidifier disinfectant lung injuries (HDLI) occurred in Korea. Human studies on mechanisms underlying HDLI have yet to be conducted. This study aimed to investigate methylation changes... -
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- Culture-Positive Spontaneous Ascitic Infection in Patients with Acute Decompensated Cirrhosis: Multidrug-Resistant Pathogens and Antibiotic Strategies
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Liu J, Gao Y, Wang X, Qian Z, Chen J, Huang Y, Meng Z, Lu X, Deng G, Liu F, Zhang Z, Li H, Zheng X
- KMID: 2468489
- Yonsei Med J.
- 2020 Feb;61(2):145-153.
- doi: 10.3349/ymj.2020.61.2.145
PURPOSE: This study investigated multidrug-resistant (MDR) pathogens and antibiotic strategies of culture-positive spontaneous ascitic infection (SAI) in patients with acute decompensated cirrhosis. MATERIALS AND METHODS: We retrospectively analyzed 432 acute decompensated... -
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- Diffuse Systemic Sclerosis in a Patient with Primary Biliary Cirrhosis and Autoimmune Hepatitis Overlap Syndrome: A Case Report
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Han HS, Ahn GR, Kim HJ, Park KY, Li K, Seo SJ
- KMID: 2467204
- Ann Dermatol.
- 2020 Feb;32(1):69-73.
- doi: 10.5021/ad.2020.32.1.69
Systemic sclerosis (SSc) is a chronic systemic disease of unknown etiology characterized by vasculopathy, excessive accumulation of extracellular matrix, and fibrosis of the skin and other internal organs. Although its... -
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- Focal Xanthogranulomatous Pyelonephritis Associated with Xanthogranulomatous Cholecystitis: A Case Report
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Cho SM, Kim HK, Lee HK, Lee B, Kim KH, Lee KE, Shim JC, Hwang DH, Lee GJ
- KMID: 2469192
- J Korean Soc Radiol.
- 2020 Jan;81(1):190-196.
- doi: 10.3348/jksr.2020.81.1.190
Xanthogranulomatous inflammation is a rare inflammatory reaction, characterized by lipid-laden macrophages, known as xanthomas, in histopathologic examination. Aggressive xanthogranulomatous inflammation often manifests as local infiltration but does not affect distant... -
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- Cystic fibrosis lung disease: Current perspectives
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Jung JA
- KMID: 2469112
- Allergy Asthma Respir Dis.
- 2020 Jan;8(1):3-8.
- doi: 10.4168/aard.2020.8.1.3
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or... -
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- Pharmacological treatment of pulmonary fibrosis
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Choi WI
- KMID: 2467985
- J Korean Med Assoc.
- 2020 Jan;63(1):47-55.
- doi: 10.5124/jkma.2020.63.1.47
Idiopathic pulmonary fibrosis (IPF) is a condition that has been described as alveolar collapse and thickening, which correlate with dysregulated surfactant production and injury to type 2 alveolar cells. As... -
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