J Korean Assoc Maxillofac Plast Reconstr Surg.  2002 May;24(3):218-225.

A Study Of The Midazolam Dosage On Conscious Sedation At The Department Of The Oral And Maxillofacial Surgery

Affiliations
  • 1Department of Oral and Maxillofacial Surgery and Research Institute of Oral Science, Korea. smin_kim@kangnung.ac.kr
  • 2Department of Pharmacology, College of Dentistry, Kangnung National University, Korea.

Abstract

Conscious sedation is a minimally depressed level of consciousness that retains the patient's ability to maintain the airway continuously and to respond appropriately to physical stimulation and verbal command at any time, produced by a pharmacologic or nonpharmacologic method or a combination thereof. In dental anesthesia,a state of sedation in which the conscious patient is rendered free of fear, apprehension and anxiety through the use of pharmacologic agents. Midazolam is a useful drug of benzodiazepine on minor operation of dentistry. The purpose of this study is to estimate the appropriate dosage protocol of Midazolam to the patient receiving intravenous sedation at the department of oral and maxillofacial surgery. Total subject was fifty-one patients and fifteen patients of this subject were decided to control group that they were not received intravenous sedation. The experimental group was randomly subdivided into two groups and each of those groups was administrated to 0.05 mg/kg and 0.08 mg/kg each other. All patients of the subject were surveyed with postoperative one day questionaire to evaluate the level of sedation. We found that the result was statistically significant between the experimental and the control, and so we present the protocol of the department of oral and maxillofacial surgery, Kangnung National University Dental Hospital.

Keyword

Conscious sedation; Midazolam; Postoperative one day questionaire

MeSH Terms

Anxiety
Benzodiazepines
Conscious Sedation*
Consciousness Disorders
Dentistry
Humans
Midazolam*
Physical Stimulation
Surgery, Oral*
Benzodiazepines
Midazolam
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