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Midazolam use in pediatric dentistry: a review

Jain SA, Rathi N, Thosar N, Baliga S

Behaviour management and dental procedures performed in very young, pre-cooperative, highly anxious, or medically disabled children are challenging tasks. Various drugs and methods have, however, been introduced to facilitate treatment...
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Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children

Akbulut UE, Kartal S, Dogan U, Akcali GE, Kalayci S, Kirci H

PURPOSE: Various publications on the use of sedation and anesthesia for diagnostic procedures in children have demonstrated that no ideal agent is available. Although propofol has been widely used for...
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Fatal pulmonary aspiration during balanced sedation with dexmedetomidine and midazolam: A case report

Park JH, Kim SY, Kwon MA

Recently, balanced sedation has commonly been used during procedural sedation. Dexmedetomidine is known for its relative safety to cause “conscious sedation” with little respiratory depression but has some limitations such...
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Using Etomidate and Midazolam for Screening Colonoscopies Results in More Stable Hemodynamic Responses in Patients of All Ages

Lee JM, Min G, Keum B, Lee JM, Kim SH, Choi HS, Kim ES, Seo YS, Jeen YT, Chun HJ, Lee HS, Um SH, Kim CD

BACKGROUND/AIMS: Recent studies have demonstrated that etomidate is a safe sedative drug with noninferior sedative effects. In our recent study, we revealed that etomidate/midazolam was more hemodynamically stable than propofol/midazolam...
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Adverse events of conscious sedation using midazolam for gastrointestinal endoscopy

Jun J, Han JI, Choi AL, Kim YJ, Lee JW, Kim DY, Lee M

BACKGROUND: This study was conducted to identify the types and incidence of adverse events associated with midazolam, which is the most widely used drug to induce conscious sedation during gastrointestinal...
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Efficacy and Safety of Fentanyl in Combination with Midazolam in Children on Mechanical Ventilation

Lee B, Park JD, Choi YH, Han YJ, Suh DI

BACKGROUND: To evaluate the efficacy and safety of fentanyl for sedation therapy in mechanically ventilated children. METHODS: This was a double-blind, randomized controlled trial of mechanically ventilated patients between 2 months...
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Analysis of the effect of oral midazolam and triazolam premedication before general anesthesia in patients with disabilities with difficulty in cooperation

Lim SW, So E, Yun HJ, Karm MH, Chang J, Lee H, Kim HJ, Seo KS

BACKGROUND: When performing dental treatment under general anesthesia in adult patients who have difficulty cooperating due to intellectual disabilities, anesthesia induction may be difficult as well. In particular, patients who...
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Comparison of the efficacy of a combination of high dose metoclopramide and dexamethasone, with that of haloperidol, midazolam and dexamethasone, for the prevention of postoperative nausea and vomiting in laparoscopic gynecologic surgery

Jee YS, Yoon HJ, Park YS, Kim DW

BACKGROUND: This prospective randomized double-blinded study was designed to compare the efficacy of a combination of high dose metoclopramide and dexamethasone with that of haloperidol, midazolam and dexamethasone, for the...
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Complications associated with intravenous midazolam and fentanyl sedation in patients undergoing minor oral surgery

Saiso K, Adnonla P, Munsil J, Apipan B, Rummasak D, Wongsirichat N

BACKGROUND: Anxiety control remains an important concern in dental practice. We evaluated the incidence, nature, and sequelae of complications during and after minor oral surgeries performed under intravenous midazolam and...
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Risk factor analysis of additional administration of sedative agent and patient dissatisfaction in intravenous conscious sedation using midazolam for third molar extraction

Shin DW, Cho JY, Han YS, Sim HY, Kim HS, Jung DU, Lee H

OBJECTIVES: The primary purpose of this study was to investigate the factors related with additional administration of sedative agent during intravenous conscious sedation (IVS) using midazolam (MDZ). The secondary purpose...
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Hemodynamic Effects of Co-administration of Midazolam during Anesthesia Induction with Propofol and Remifentanil in Hypertensive Patients

Kim JD, Kim JW, Kung HC, Kang JH, Shin HY, Kim DS, Ryu SJ, Kim KH

OBJECTIVES: Propofol, midazolam and remifentanil are commonly used for clinical anesthesia. We compared the effects of midazolam-propofol-remifentanil and propofol-remifentanil on hemodynamic responses during anesthesia induction in hypertensive patients. METHODS: Seventy-six hypertensive...
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Population Pharmacokinetics of Midazolam in Healthy Koreans: Effect of Cytochrome P450 3A-mediated Drug-drug Interaction

Shin KH

OBJECTIVE: Midazolam is mainly metabolized by cytochrome P450 (CYP) 3A. Inhibition or induction of CYP3A can affect the pharmacological activity of midazolam. The aims of this study were to develop...
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The effects of etomidate and midazolam on adipose tissue-derived mesenchymal stem cell proliferation

Park H, Ryu K, Kim YH, Choi WJ, Ko D

BACKGROUND: Stem cell therapy using adipose tissue-derived mesenchymal stem cells (ADSCs), which are capable of multipotent differentiation, is currently being investigated in the field of tissue regeneration and the treatment...
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Anaphylactic shock caused by intramuscular injection of midazolam during the perioperative period: a case report

Kim KN, Kim DW, Sin YH, Lee SK

Although anaphylactic shock during the perioperative period is rare, it can be lethal due to severe cardiovascular and respiratory collapse. Midazolam is generally used as premedication for relieving anxiety about...
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Dexmedetomidine combined with midazolam vs. dexmedetomidine alone for sedation during spinal anesthesia

Yoon DK, Ban JS, Lee SG, Lee JH, Kim E, An J

BACKGROUND: Dexmedetomidine is a useful sedative agent for spinal anesthesia. However, it has been reported that dexmedetomidine decreases heart rate in a dose-dependent manner. In the current study, we compared...
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Decreased absorption of midazolam in the stomach due to low pH induced by co-administration of Banha-sasim-tang

Jo JH, Kim SJ, Nam WS, Seung EJ, Lee S

OBJECTIVES: Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is...
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Efficacy and Safety of Low Dose Ketamine and Midazolam Combination for Diagnostic Upper Gastrointestinal Endoscopy in Children

Akbulut UE, Cakir M

PURPOSE: We aimed to analyze the effectiveness and safety of low-dose midazolam and ketamine combination for upper gastrointestinal endoscopy (UGIE) in children. METHODS: The study included the children (n=425, 10.78+/-3.81 years)...
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Considerations for submucosal midazolam administration in combination with oral and inhaled medications for sedation of pediatric dental patients

Baek K

  • KMID: 2310710
  • J Dent Anesth Pain Med.
  • 2015 Jun;15(2):47-52.
Sedation allows patients to maintain their airway independently and respond appropriately to physical stimulation and verbal command while maintaining a minimum depressed level of consciousness. Drugs commonly used for sedation...
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Anesthesia awareness. Can midazolam attenuate or prevent memory consolidation on intraoperative awakening during general anesthesia without increasing the risk of postoperative delirium?

Cascella M

No abstract available.
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Complete resolution of myoclonus-like involuntary movements under subarachnoid block after midazolam administration in a patient undergoing cesarean section: a case report

Nakamoto T, Hirota K, Iwai T, Shingu K

Involuntary movement during and after neuraxial anesthesia, such as spinal and epidural anesthesia, is rarely observed. In this report, we describe a case of myoclonus-like involuntary movement of the upper...
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