Korean J Anesthesiol.  1997 May;32(5):745-749. 10.4097/kjae.1997.32.5.745.

Induction of Anesthesia with Low-Dose Midazolam and Thiopental

• Na YD
• Jang YH
• Chung JK

• KMID: 2240232
• DOI: http://doi.org/10.4097/kjae.1997.32.5.745

Abstract

BACKGROUND
This study was undertaken to evaluate the hemodynamic response of midazolam-thiopental coinduction technique compared with thiopental or midazolam induction after tracheal intubation.
METHODS
60 patients were divided into 3 groups. Group I thiopental 5 mg/kg induction groups: Group II, midazolam 0.2 mg/kg induction group: Group III 2 mg/kg of thiopental was injected intravenously to each patient 2min after 0.02 mg/kg of midazolam injected. After tracheal intubation, blood pressure and heart rate were measured for 5 minutes at 1 minute interval.
Results
There were not significant differences in systolic, diastotic, mean arterial pressure and heart rate in 3 groups.
CONCLUSIONS
Low dose midazolam-thiopental coinduction can be a useful method for induction because of same hemodynamic changes as to thiopental or midazolam alone.

Keyword

Anesthetics; intravenous; midazolam; thiopental

MeSH Terms

Anesthesia*
Anesthetics
Arterial Pressure
Blood Pressure
Heart Rate
Hemodynamics
Humans
Intubation
Midazolam*
Thiopental*
Anesthetics
Midazolam
Thiopental