Prospective clinical study of midazolam sedation in patients undergoing dental practice

Kim, Seong Gon

Abstract

PURPOSE: The objective of this study was to evaluate the clinical parameters in terms of the midazolam sedation in patients undergoing dental practice.
PATIENTS AND METHODS
Total 28 patients were included in this study. They received the dental practice in the daycare center and sedation was done with midazolam. The recorded variables were blood pressure, pulse rate, SpO2, and patient's response. The differences between observations were analyzed with paired samples t-test.
RESULTS
The blood pressure was significantly decreased after the administration of midazolam and the systolic pressure was significantly increased at the start of operation (P<0.05). The pulse rate was significantly increased after lidocaine injection (P<0.001). The amnesic effect was shown 21 cases out of 28 cases (75 %).
CONCLUSIONS
The effect of midazolam on pulse rate was not significant. However, midazolam could decrease the blood pressure significantly. Therefore, the sedation with midazolam could be successfully used in the dental practice, particularly for the patients having the hypertension.