J Korean Surg Soc.  2011 Nov;81(5):316-320. 10.4174/jkss.2011.81.5.316.

Coexistence of parathyroid adenoma and papillary thyroid carcinoma

• Lee YS
• Nam KH
• Chung WY
• Chang HS
• Park CS

• KMID: 2096684
• DOI: http://doi.org/10.4174/jkss.2011.81.5.316

Abstract

PURPOSE
Although several reports have been published regarding the coexistence of hyperparathyroidism and papillary thyroid carcinomas, concurrence of parathyroid adenoma and papillary thyroid carcinoma is extremely rare. The aim of this study was to describe experiences with concurrent parathyroid adenoma and papillary thyroid carcinoma.
METHODS
Seven patients with concurrent parathyroid adenoma and papillary thyroid carcinoma were identified between January 2006 and December 2007, and their medical records were reviewed retrospectively.
RESULTS
Of the seven patients identified, three were male and four were female; their mean age was 53.6 years. None of the patients presented with symptomatic hyperparathyroidism preoperatively. On laboratory findings, four patients had mild to moderate hypercalcemia, but serum parathyroid hormone concentrations were high in all patients. Preoperative imaging showed suspicious features of diseased parathyroid glands in four patients; two upon ultrasonography and computed tomography together and two upon ultrasonography only. The coexistence of parathyroid adenoma did not affect the extent of thyroid surgery. Laboratory values after surgery returned to within normal ranges in all patients.
CONCLUSION
It is important not only to analyze serum calcium levels but also to carefully interpret imaging studies in order to identify asymptomatic hyperparathyroidism when performing thyroid cancer surgery.

Keyword

Parathyroid neoplasms; Papillary thyroid cancer

MeSH Terms

Calcium
Carcinoma
Humans
Hypercalcemia
Hyperparathyroidism
Male
Medical Records
Parathyroid Glands
Parathyroid Hormone
Parathyroid Neoplasms
Reference Values
Thyroid Gland
Thyroid Neoplasms
Calcium
Carcinoma
Parathyroid Hormone
Thyroid Neoplasms

Figure

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  Fig. 1 Preoperative (preop) and postoperative (postop) laboratory values changes.

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  Fig. 2 Left hemithyroidectomy and left superior parathyroid adenoma (white arrow) specimen.

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