Korean J Otorhinolaryngol-Head Neck Surg.
2008 Jun;51(6):566-569.
Synchronous Parathyroid Adenoma and Papillary Thyroid Carcinoma
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- 1Department of Otorhinolaryngology, College of Medicine and Research Center for Sensory Organs, Medical Research Center, Seoul National University, Seoul, Korea. mwsung@snu.ac.kr
Abstract
- Primary hyperparathyroidism with concomitant thyroid disease is common. However, the simultaneous occurrence of parathyroid adenoma and thyroid cancer is rare. We report a 55-year-old man with primary hyperparathyroidism who presented with chest tightness. In this patient, preoperative imaging studies for diagnosis revealed the presence of nodules in right parathyroid gland and left inferior pole of thyroid gland. However, Tc-MIBI scintigraphy did not localize parathyroid lesion. We performed technique of intraoperative methylene blue infusion for localization of parathyroid. The right parathyroid lesion was easily detected and right parathyroidectomy was performed successfully. After parathyroidectomy, the left thyroid lesion was confirmed to papillary carcinoma by frozen biopsy. The patient consecutively underwent total thyroidectomy. Pathology revealed parathyroid adenoma with concurrent papillary thyroid carcinoma. The coexistence of parathyroid adenoma and thyroid malignancy was possible for all patients in primary hyperparathyroidism with thyroid nodules. Therefore, careful thyroid evaluation must be necessary for all patients with primary hyperparathyroidism.
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