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Analysis of the cause and management of persistent laboratory abnormalities occurring after the surgical treatment of primary hyperparathyroidism

Lee JE, Hong N, Kim JK, Lee CR, Kang SW, Jeong JJ, Nam KH, Chung WY, Rhee Y

Purpose: The surgical success rate for primary hyperparathyroidism (PHPT) is currently 95%–98%. However, 3%–24% of patients show persistently elevated (Pe) parathyroid hormone (PTH) levels after parathyroidectomy (PTX). This singlecenter retrospective...
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Comparisons Between Normocalcemic Primary Hyperparathyroidism and Typical Primary Hyperparathyroidism

Choi HR, Choi SH, Hong N, Rhee Y, Kim JK, Lee CR, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY

Background: Normocalcemic primary hyperparathyroidism (NPHPT) was first described in 2008. It is defined as consistently elevated serum parathyroid hormone (PTH) levels with normal serum calcium (sCa) concentration, after excluding secondary...
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The First Korean Family With Boucher-Neuhäuser Syndrome Carrying a Novel Mutation in PNPLA6

Chung EJ, You E, Oh SH, Seo GH, Chung WY, Kim YJ, Kim SJ

No abstract available.
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A MAST1 Mutation Underlying Mega-Corpus Callosum Syndrome with Extended Phenotypes: The First Case in Korea

Hur YJ, Chung WY, Lim YJ, Park S, Jun KR

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Lactate Dehydrogenase A as a Potential New Biomarker for Thyroid Cancer

Ban EJ, Kim D, Kim JK, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY, Kim K

Background: Several cancers show increased levels of lactate dehydrogenase A (LDHA), which are associated with cancer progression. However, it remains unclear whether LDHA levels are associated with papillary thyroid cancer...
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An A627V-activating mutation in the thyroid-stimulating hormone receptor gene in familial nonautoimmune hyperthyroidism

Shin JH, Seo GH, Oh SH, Chung WY, Kim HY, Kim YM, Bae MH, Park KH, Kwak MJ

Nonautoimmune hyperthyroidism is a very rare cause of congenital hyperthyroidism that is usually caused by an activating mutation in the thyroid-stimulating hormone receptor (TSHR) gene. In this report, we describe...
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Long-term outcomes of abdominal paraganglioma

Choi HR, Yap Z, Choi SM, Choi SH, Kim JK, Lee CR, Lee J, Jeong JJ, Nam KH, Chung WY, Kang SW

Purpose: Paragangliomas (PGL) are rare neuroendocrine tumors derived from chromaffin cells of the autonomic nervous system. We aim to describe our experience and the long-term outcome of abdominal PGL over...
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Identification of a heterozygous ACAN mutation in a 15-year-old boy with short stature who presented with advanced bone age: a case report and review of the literature

Kim TY, Jang KM, Keum CW, Oh SH, Chung WY

Longitudinal bone growth is primarily mediated by the growth plate, which is a specialized cartilaginous structure. Aggrecan, encoded by ACAN, is a primary proteoglycan component of the extracellular matrix in...
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Is the Internal Jugular Node Dissection without Level V Sufficient in Patients with Papillary Thyroid Carcinoma with Lateral Neck Node Metastasis?

Lee CR, Kim JK, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY

Purpose: Papillary thyroid carcinoma (PTC) has a high rate of lateral neck node metastases, and completeness of surgical resection is an important determinant of outcomes. The appropriate extent of therapeutic...
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Effects of long-term growth hormone therapy in a girl with Floating-Harbor syndrome

Son HW, Lee JE, Oh SH, Keum C, Chung WY

Floating-Harbor syndrome is a rare autosomal dominant disorder that presents with short stature, facial dysmorphism, significantly delayed bone age, skeletal abnormalities, speech and language problems, and intellectual disabilities. Although short...
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Characteristics of Interstitial Deletion in Chromosome 4q Confirmed by Array Comparative Genomic Hybridization: A Case Report and Literature Review

Chung WY, Lee SJ, Kim HR, Jun KR

Chromosome 4q deletion syndrome is a rare disease caused by partial deletion of the long arm of chromosome 4. Phenotypic severity and expressivity vary among patients with chromosome 4q deletions,...
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The Prevention of Contrast Induced Nephropathy by Sarpogrelate: a Prospective Randomized Controlled Clinical Trial

Ki YJ, Kwon SA, Kim HL, Seo JB, Chung WY

BACKGROUND: Although some strategies are used for prophylaxis of contrast induced nephropathy, their efficacy is not fully established. Sarpogrelate can relieve vasospasm and have anti-inflammatory action. This study examined whether...
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Association between BRAF(V600E) Mutations and Clinicopathological Features of Papillary Thyroid Microcarcinoma (PTMC)

Lee SM, Lee CR, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY, Park CS

PURPOSE: In this study, the relationship between the BRAF(V600E) mutation and the clinicopathological features of papillary thyroid microcarcinoma (PTMC) was examined in a single center. METHODS: From January 2011 to December...
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Role of proteases, cytokines, and growth factors in bone invasion by oral squamous cell carcinoma

Son SH, Chung WY

Oral squamous cell carcinoma (OSCC) is the most common oral malignancy and an increasing global public health problem. OSCC frequently invades the jaw bone. OSCC-induced bone invasion has a significant...
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Gender difference in the association between brachial-ankle pulse wave velocity and cardiovascular risk scores

Rhee TM, Kim HL, Oh S, Lim WH, Seo JB, Chung WY, Kim SH, Kim MA, Zo JH

BACKGROUND/AIMS: Although brachial-ankle pulse wave velocity (baPWV) has been validated as a novel method to predict the cardiovascular risk in general population, the relevance of baPWV to the traditional risk...
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Surgical outcomes of laparoscopic adrenalectomy for primary hyperaldosteronism: 20 years of experience in a single institution

Kim K, Kim JK, Lee CR, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY

PURPOSE: Recently, posterior retroperitoneoscopic adrenalectomy (PRA) has been reported to have some advantages over laparoscopic transperitoneal adrenalectomy (LTA). The objectives of this study were to report our experience over 12...
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Symptomatic Calcific Deposition in Posterior Cruciate Ligament of the Knee

Chung WY, Park SJ, Sung SY

Calcium deposition disease, including calcific tendinitis, rarely affects the knee joint. Only a few cases can be found in the literatures and there is no case report of symptomatic calcific...
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Changes in the thyroid hormone profiles in children with nephrotic syndrome

Jung SH, Lee JE, Chung WY

PURPOSE: We compared thyroid hormone profiles in children with nephrotic syndrome (NS) during the nephrotic phase and after remission. METHODS: This study included 31 pediatric NS patients. The thyroid hormone profiles...
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Novel SLC5A2 Mutations and Genetic Characterization in Korean Patients with Familial Renal Glucosuria

Lee WK, Oh SH, Chung WY

PURPOSE: Familial renal glucosuria (FRG, OMIM #233100) is a rare but relatively benign genetic condition characterized by persistent isolated glucosuria with a normal blood glucose level. We report three additional...
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Usefulness of dynamic risk stratification in pediatric patients with differentiated thyroid carcinoma

Kim K, Kim WW, Choi JB, Kim MJ, Lee CR, Lee J, Kang SW, Nam KH, Chung WY, Jeong JJ

PURPOSE: Recently, the American Thyroid Association (ATA) dynamic risk stratification (DRS) has been verified to be more valuable than the static anatomical staging system for predicting prognosis in patients with...
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