Korean Circ J.  1998 Aug;28(8):1387-1392. 10.4070/kcj.1998.28.8.1387.

A Case of Beneficial Effect of Short-Term Growth Hormone Treatment for Intractable Heart Failure in Cardiomyopathy Combined with Neuromuscular Dystrophy

• Byun KH
• Kim D
• Kna JS
• Oh SH
• Kim IJ
• Hong BK
• Kwon H
• Nam SY
• Kang SW
• Kim HS

• KMID: 2093665
• DOI: http://doi.org/10.4070/kcj.1998.28.8.1387

Abstract

We report a case of 15-year-old man with beneficial effects of short term growth hormone treatment presenting with cardiomyopathy combined with neuromuscular dystrophy. Transthoracic echocardiography revealed that LV chamber was markedly dilated and global LV systolic function was severely reduced. The findings of electromyography were compatible with neuromuscular dystrophy. Under the impression of cardiomyopathy combined with neuromuscular disease, maximal medical treatments such as inotropic agents, diuretics and ACE inhibitor were tried but we could not attain remarkable clinical improvement. Finally, we started growth hormone injection and after treatment for 3 months, we could attain remarkable clinical and hemodynamic improvement without any side effect.

Keyword

Cardiomyopathy; Growth hormone therapy; Neuromuscular dystrophy

MeSH Terms

Adolescent
Cardiomyopathies*
Diuretics
Echocardiography
Electromyography
Growth Hormone*
Heart Failure*
Heart*
Hemodynamics
Humans
Neuromuscular Diseases
Diuretics
Growth Hormone