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Local Injection of Growth Hormone for Temporomandibular Joint Osteoarthritis

Ok SM, Kim JH, Kim JS, Jeong EG, Park YM, Jeon HM, Heo JY, Ahn YW, Yu SN, Park HR, Kim KH, Ahn SC, Jeong SH

PURPOSE: Osteoarthritis (OA) of the temporomandibular joint (TMJ) elicits cartilage and subchondral bone defects. Growth hormone (GH) promotes chondrocyte growth. The aim of this study was to evaluate the efficacy...
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Live birth outcomes of vitrified embryos generated under growth hormone stimulation are improved for women categorized as poor-prognosis

Keane KN, Ye Y, Hinchliffe PM, Regan SL, Dhaliwal S, Yovich JL

OBJECTIVE: To determine the clinical pregnancy (CP) and live birth (LB) rates arising from frozen embryo transfers (FETs) that had been generated under the influence of in vitro fertilization (IVF)...
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Correlation between genetic heterogeneity and variability for response to growth hormone in Noonan syndrome

Shin YL

No abstract available.
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A Case of Adipsic Hypernatremia in a Patient with Panhypopituitarism Treated with Growth Hormone Replacement

Mhun EH, Lee JH, Lee DH

Adipsic hypernatremia is a rare disease where patients do not feel thirst even in the increased serum osmotic pressure and results in electrolyte imbalance, severely increased osmotic pressure and neurologic...
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Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy

Kim MS, Koh HJ, Lee GY, Kang DH, Kim SY

PURPOSE: This study aimed to investigate the outcomes of gonadotropin-releasing hormone agonist (GnRHa) therapy with or without growth hormone (GH) therapy for girls with idiopathic central precocious puberty (CPP). METHODS: The...
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Risk of cancer in patients treated with recombinant human growth hormone in childhood

Cianfarani S

Recombinant human growth hormone (GH) has been in use for over 30 years, and its indications have gradually expanded from the classical replacement therapy in GH deficiency (GHD) to pharmacological...
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Impaired Cortisol and Growth Hormone Counterregulatory Responses among Severe Hypoglycemic Patients with Type 2 Diabetes Mellitus

Rhyu YA, Jang JY, Park S, An JH, Kim DL, Kim SK, Song KH

BACKGROUND: Elevated levels of cortisol and growth hormone are critical counterregulatory responses to severe hypoglycemia. However, the proportion and clinical characteristics of patients with type 2 diabetes mellitus (DM) who...
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Intra-articular Recombinant Human Growth Hormone Injection Compared with Hyaluronic Acid and Placebo for an Osteoarthritis Model of New Zealand Rabbits

Lubis AM, Wonggokusuma E, Marsetio A

PURPOSE: Up to now, there is no feasible solution for stopping or reversing the degenerative process of osteoarthritis (OA). Our study evaluated the effect of intra-articular injection of growth hormone...
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Growth Hormone and Aging: Updated Review

Bartke A

Role of growth hormone (GH) in mammalian aging is actively explored in clinical, epidemiological, and experimental studies. The age-related decline in GH levels is variously interpreted as a symptom of...
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Growth hormone therapy in patients with Noonan syndrome

Seo GH, Yoo HW

Noonan syndrome (NS) is an autosomal dominant disorder that involves multiple organ systems, with short stature as the most common presentation (>70%). Possible mechanisms of short stature in NS include...
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The role of p21/CIP1/WAF1 (p21) in the negative regulation of the growth hormone/growth hormone receptor and epidermal growth factor/epidermal growth factor receptor pathways, in growth hormone transduction defect

Kostopoulou E, Rojas Gil , Spiliotis

PURPOSE: Growth hormone transduction defect (GHTD) is characterized by severe short stature, impaired STAT3 (signal transducer and activator of transcription-3) phosphorylation and overexpression of the cytokine inducible SH2 containing protein...
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Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats

Lee J, Kwon A, Chae HW, Lee WJ, Kim TH, Kim HS

PURPOSE: Growth hormone secretagogues (GHSs) possess the ability to release growth hormone (GH) in the body. This study aimed to investigate the effects of MK-677, an orally active GHS, on...
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Design of the long-term observational cohort study with recombinant human growth hormone in Korean children: LG Growth Study

Chung S, Yoo JH, Choi JH, Rhie YJ, Chae HW, Kim JH, Hwang IT, Shin CH, Kim EY, Lee KH

PURPOSE: Regarding recombinant human growth hormone (rhGH) use in the pediatric population, no long-term follow-up data are available for Korean patients. To fill in the gap of knowledge, a registry...
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Effect of Recombinant Human Growth Hormone Add on Therapy on Acute Stroke Outcome

Jin GH, Lee JB

Recombinant human growth hormone (rhGH) administration stimulate the secretion of the brain insulin-like growth factor-1 (IGF-1) concentration and IGF-1 is a pleiotropic neurotropic peptide to exert beneficial effect for the...
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Prepubertal growth and single nucleotide polymorphism analysis of the growth hormone gene of low birth weight Holstein calves

Ro Y, Choi W, Kim H, Jang H, Lee H, Lee Y, Kim D

Holstein calves weighing less than 20 kg at birth have been noted in Korea. Due to insufficient information, we raised small calves with age-matched normal birth weight Holstein calves and...
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Effects of growth hormone on glucose metabolism and insulin resistance in human

Kim SH, Park MJ

Growth hormone (GH) is important for promotion of somatic growth and the regulation of substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver, muscle, fat and...
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Effect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency

Im M, Kim YD, Han HS

PURPOSE: There are inconsistencies in the results reported in a small number of previous studies into growth hormone (GH) treatment in Korean children with idiopathic short stature (ISS) and idiopathic...
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Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome

Lee SS, Han AL, Ahn MB, Kim SH, Cho WK, Cho KS, Park SH, Jung MH, Suh BK

Growth hormone (GH) is an essential element for normal growth. However, reports of normal growth without GH have been made in patients who have undergone brain surgery for craniopharyngioma. Normal...
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Concomitant occurrence of Turner syndrome and growth hormone deficiency

Yu J, Shin HY, Lee CG, Kim JH

Turner syndrome (TS) is a genetic disorder in phenotypic females that has characteristic physical features and presents as partial or complete absence of the second sex chromosome. Growth hormone deficiency...
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A Case of Acanthosis Nigricans Induced by Growth Hormone Therapy

Na CH, Youn SH, Kim MS, Shin BS

  • KMID: 2162231
  • Korean J Dermatol.
  • 2016 Mar;54(3):222-223.
No abstract available.
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