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Hypertrophic Cardiomyopathy in Infants from the Perspective of Cardiomyocyte Maturation

Seok H, Oh JH

Hypertrophic cardiomyopathy (HCM) is characterized by ventricular wall hypertrophy with diastolic dysfunction. Pediatric HCM is distinguished from the adult in many aspects. Most children with HCM do not present clinically...
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Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis

Hanumanthu BKJ, Nair AS, Katamreddy A, Gilbert JS, You JY, Offor OL, Kushwaha A, Krishnan A, Napolitano M, Palaidimos L, Morante J, Tekwani SS, Mehta S, Gupta A, Goraya H, Sun M, Faillace RT, Gulani P

Background: Patients with sepsis are at risk for developing sepsis-induced cardiomyopathy (SIC). Previous studies offer inconsistent results regarding the association of SIC and mortality. This study sought to assess whether...
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Transthyretin Cardiac Amyloidosis: A Case Report

Chin ZY, Chew D, Khor LY, Liew C

We report a case of a 63-year-old Chinese female with multi-systemic amyloidosis associated with transthyretin mutation. She presented with gastrointestinal symptoms, sensorimotor polyneuropathy, and loss of weight. Her initial CT...
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Novel Resectable Myocardial Model Using Hybrid Three-Dimensional Printing and Silicone Molding for Mock Myectomy for Apical Hypertrophic Cardiomyopathy

Kim W, Lim M, Jang YJ, Koo HJ, Kang JW, Jung SH, Yang DH

Objective: We implemented a novel resectable myocardial model for mock myectomy using a hybrid method of threedimensional (3D) printing and silicone molding for patients with apical hypertrophic cardiomyopathy (ApHCM). Materials and...
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Free-Breathing Motion-Corrected Single-Shot Phase-Sensitive Inversion Recovery Late-Gadolinium-Enhancement Imaging: A Prospective Study of Image Quality in Patients with Hypertrophic Cardiomyopathy

Cha MJ, Cho I, Hong J, Kim SW, Shin SY, Paek MY, Bi X, Kim SM

Objective: Motion-corrected averaging with a single-shot technique was introduced for faster acquisition of late-gadoliniumenhancement (LGE) cardiovascular magnetic resonance (CMR) imaging while free-breathing. We aimed to evaluate the image quality (IQ)...
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Early Differentiation of Stress Cardiomyopathy from Acute Anterior Wall Myocardial Using Changing Cardiac Enzyme Patterns

Hong JY, Ryu SK, Park JY, Park SH, Choi J

BACKGROUND: Most patients with acute anterior wall ST elevation myocardial infarction (STEMI) or stress cardiomyopathy (SCMP) show elevations in cardiac enzymes that peak within 24 hours. The changing pattern of...
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An Unusual Case of Shock in an Octogenarian

Chen MA

An octogenarian presented to our hospital in shock after being “found down” at home. She was dehydrated, hypernatremic, and suffering from a urinary tract infection. Findings of a murmur and...
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Hypertrophic cardiomyopathy with  paroxysmal atrial fibrillation misdiagnosed as WPW syndrome

Seol S, Kim K, Park J, Song Y, Kim D, Kim D

Hypertrophic cardiomyopathy (HCM) is associated with an increased incidence of Wolff–Parkinson–White (WPW) syndrome and atrial fibrillation. However, a delta-like wide QRS can be observed in the hypertrophied myocardium. When considering...
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A Neonate Diagnosed with Wolff-Parkinson-White Syndrome Presenting with Cardiogenic Shock

Ha JE, Lee SH, Park GY, Shin YL, Kim SS, Jang MA

We present the case of a healthy 28-day-old female full-term neonate who was admitted to the neonatal intensive care unit for severe metabolic acidosis, hypoglycemia, and an initial sinus rhythm....
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Ventricular Arrhythmia Burden as a Marker of Success Following Catheter Ablation of Ventricular Arrhythmias in Patients with Structural Heart Disease

Bennett R, Turnbull S, Kotake Y, Campbell T, Kumar S

Background and Objectives: There is little emphasis on the efficacy of catheter ablation for ventricular arrhythmia (VA) when using VA burden reduction as a marker for success. We examined the...
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The Extent of Late Gadolinium Enhancement Can Predict Adverse Cardiac Outcomes in Patients with Non-Ischemic Cardiomyopathy with Reduced Left Ventricular Ejection Fraction: A Prospective Observational Study

Kim EK, Lee GY, Jang SY, Chang SA, Kim SM, Park SJ, Choi JO, Park SW, Choe YH, Lee SC, Oh JK

Objective: The clinical course of an individual patient with heart failure is unpredictable with left ventricle ejection fraction (LVEF) only. We aimed to evaluate the prognostic value of cardiac magnetic...
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Genetics of Cardiomyopathy: Clinical and Mechanistic Implications for Heart Failure

Kim KH, Pereira NL

Genetics has played an important role in the understanding of different cardiomyopathies, and the field of heart failure (HF) genetics is progressing rapidly. Much research has also focused on distinguishing...
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Identifying Adverse Remodeling in Hypertrophic Cardiomyopathy Phenotypes Role of Left Atrial Parameters

Dutt S, Tandon R, Sondh MS, Bansal N, Singh G, Mohan B, Singh B, Wander GS

Objective: Documenting adverse remodeling in absence of left ventricular outflow tract (LVOT) obstruction and mitral regurgitation in a classical hypertrophic cardiomyopathy (HCMP) phenotype is difficult. Changes in the left atrium...
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Left-Dominant ArrhythmogenicCardiomyopathy: A Rare andFrequently MisdiagnosedCardiomyopathy Associated withHeart Failure

Cui C, Wang X, Zhao S

A 35-year-old male with 7-year history of exertional dyspnea and abdominal distention hadfrequent premature ventricular contractions detected by Holter monitoring. Cardiovascularmagnetic resonance (CMR) imaging demonstrated a significantly dilated left ventricle...
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Stereotactic Cardiac Radiation to Control Ventricular Tachycardia and Fibrillation Storm in a Patient with Apical Hypertrophic Cardiomyopathy at Burnout Stage: Case Report

Park JS, Choi Y

Stereotactic cardiac radiation for ablation (radioablation) of life-threatening ventricular arrhythmia was recently introduced into clinical practice. A 76-year-old male patient with apical hypertrophic cardiomyopathy at burnout stage, who received defibrillator...
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The relationship between J wave and ventricular tachycardia during Takotsubo cardiomyopathy

Choi S, Lee O, Yoon G, Kwon S, Shin S, Park S, Woo S, Kwan J, Kim D, Baek Y

Background and objectives: Takotsubo cardiomyopathy (TTC) occasionally causes life-threatening ventricular arrhythmia. J wave on surface electrocardiography (sECG) has also been associated with idiopathic ventricular fibrillation and cardiac events; therefore, we...
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Left Ventricular Global Longitudinal Strain as a Predictor for Left Ventricular Reverse Remodeling in Dilated Cardiomyopathy

Jung IH, Park JH, Lee JA, Kim GS, Lee HY, Byun YS, Kim BO

BACKGROUND: A considerable number of patients with dilated cardiomyopathy (DCM) experience left ventricular reverse remodeling (LVRR). LV global longitudinal strain (LV GLS) offers sensitive and reproducible measurement of myocardial dysfunction....
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Extracorporeal membrane oxygenation for takotsubo cardiomyopathy that developed after mitral valve replacement

Choi JH, Oh ID, Shin E, Lee S, Jeon JM, Kim HT, Youn HC

Takotsubo cardiomyopathy is a transient systolic and diastolic left ventricular dysfunction that presents several wall-motion abnormalities, while the coronary artery shows normal findings. Because patients with Takotsubo cardiomyopathy present with...
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Association between Left Ventricular Systolic Dysfunction and Mortality in Patients with Septic Shock

Kim S, Lee JD, Kim BK, Kim YH, Kim JH

BACKGROUND: The impact of myocardial damage on the prognosis of patients with septic shock is not clearly elucidated because complex hemodynamic changes in sepsis obscure the direct relationship. We evaluated...
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Intramyocardial Transplantation of Umbilical Cord Mesenchymal Stromal Cells in Chronic Ischemic Cardiomyopathy: A Controlled, Randomized Clinical Trial (HUC-HEART Trial)

Ulus AT, Mungan C, Kurtoglu M, Celikkan FT, Akyol M, Sucu M, Toru M, Gul SS, Cinar O, Can A

Background and Objectives: The HUC-HEART Trial (ClinicalTrials.gov Identifier: NCT02323477) was a controlled, prospective, phase I/II, multicenter, single-blind, three-arm randomized study of intramyocardial delivery of human umbilical cord-derived mesenchymal stromal cells...
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