Korean J Clin Pathol.
1998 Jun;18(2):122-125.
Unusual Morphology of Eosinophil Nucleus: Presented with Double Chromatin Filament Bridge: Report of Three Cases
- Affiliations
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- 1Department of Clinical Pathology, Incheon Red Cross Hospital, Incheon, Korea.
- 2Department of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
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We found an unusual morphology of eosinophil nucleus having longer chromatin filament in addition to a single narrow chromatin bridge. The nucleus having two chromatin filament bridge looked like two legged eosinophil, instead of usual glasses shape. As the physiologic function of the nucleus of granulocyte segmentation and the mechanism by which the lobes are formed during differention is still unknown, we could not know the definite nature and significance of these double chromatin filament. However we could suggest that they may be a reactive change of eosinophilia. This not uncommon morphology has not been described as yet. Here we report three cases of unusual morphology of eosinophil nucleus presenting double chromatin filament bridge, one case with a band form nucleus looked like ring shape, with brief review of literatures.