- Correlation of human sperm chromatin heterogeneity with sperm penetration assay
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Lee PR, Pang MG, Moon SY, Chang YS
- KMID: 1697211
- Korean J Obstet Gynecol.
- 1993 Jun;36(6):784-799.
No abstract available. -
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- Unusual Morphology of Eosinophil Nucleus: Presented with Double Chromatin Filament Bridge: Report of Three Cases
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Kim AS, Kong YH, Kim JY
- KMID: 2089490
- Korean J Clin Pathol.
- 1998 Jun;18(2):122-125.
We found an unusual morphology of eosinophil nucleus having longer chromatin filament in addition to a single narrow chromatin bridge. The nucleus having two chromatin filament bridge looked like two... -
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- Effects of estrogen receptor and estrogen on the chromatin structure in estrogen receptor stable transfectants
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Lee YJ, Lim WC, Jin YH, Lee SK
- KMID: 1081457
- Exp Mol Med.
- 2002 May;34(2):95-99.
The estrogen receptor (ER), a member of the nuclear hormone receptor superfamily recruits coactivators that modify local chromatin structure. Here we investigated the effect of the estrogen receptor and estrogen... -
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- CTCF, Cohesin, and Chromatin in Human Cancer
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Song SH, Kim TY
- KMID: 2404047
- Genomics Inform.
- 2017 Dec;15(4):114-122.
- doi: 10.5808/GI.2017.15.4.114
It is becoming increasingly clear that eukaryotic genomes are subjected to higher-order chromatin organization by the CCCTC-binding factor/cohesin complex. Their dynamic interactions in three dimensions within the nucleus regulate gene... -
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- A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of Roadmap Genomics ChromHMM Annotations: A Computational Perspective
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Park HS
- KMID: 2439217
- Genomics Inform.
- 2018 Dec;16(4):e27.
- doi: 10.5808/GI.2018.16.4.e27
The non-coding DNA in eukaryotic genomes encodes a language that programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this study was to determine the effect... -
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- Methylation and demethylation of DNA and histones in chromatin: the most complicated epigenetic marker
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Youn HD
- KMID: 2382712
- Exp Mol Med.
- 2017 Apr;49(4):e321.
- doi: 10.1038/emm.2017.38
No abstract available. -
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- Genetic Architecture of Transcription and Chromatin Regulation
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Kim K, Bang H, Lee K, Choi JK
- KMID: 2009145
- Genomics Inform.
- 2015 Jun;13(2):40-44.
- doi: 10.5808/GI.2015.13.2.40
DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic... -
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- Human Transcriptome and Chromatin Modifications: An ENCODE Perspective
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Shen L, Choi I, Nestler EJ, Won KJ
- KMID: 1494258
- Genomics Inform.
- 2013 Jun;11(2):60-67.
- doi: 10.5808/GI.2013.11.2.60
A decade-long project, led by several international research groups, called the Encyclopedia of DNA Elements (ENCODE), recently released an unprecedented amount of data. The ambitious project covers transcriptome, cistrome, epigenome,... -
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- Epigenetic regulation and chromatin remodeling in learning and memory
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Kim S, Kaang BK
- KMID: 2367527
- Exp Mol Med.
- 2017 Jan;49(1):e281.
- doi: 10.1038/emm.2016.140
Understanding the underlying mechanisms of memory formation and maintenance has been a major goal in the field of neuroscience. Memory formation and maintenance are tightly controlled complex processes. Among the... -
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- A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of ENCODE/Broad ChromHMM Annotations: A Computational Perspective
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Park HS
- KMID: 2422814
- Genomics Inform.
- 2018 Sep;16(3):65-70.
- doi: 10.5808/GI.2018.16.3.65
The non-coding DNA in eukaryotic genomes encodes a language which programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this short report was to determine the... -
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- Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors
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Lee JH, Kang MW, Choi C, Juhng SW
- KMID: 2172398
- Chonnam Med J.
- 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- A Review of Three Different Studies on Hidden Markov Models for Epigenetic Problems: A Computational Perspective
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Lee KE, Park HS
- KMID: 2391489
- Genomics Inform.
- 2014 Dec;12(4):145-150.
- doi: 10.5808/GI.2014.12.4.145
Recent technical advances, such as chromatin immunoprecipitation combined with DNA microarrays (ChIp-chip) and chromatin immunoprecipitation-sequencing (ChIP-seq), have generated large quantities of high-throughput data. Considering that epigenomic datasets are arranged over... -
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- A study of Digital Image Analysis of Chromatin Texture for Discrimination of Thyroid Neoplastic Cells
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Juhng SW, Lee JH, Bum EK, Kim CW
- KMID: 2226488
- Korean J Cytopathol.
- 1996 Jun;7(1):23-30.
Chromatin texture, which partly reflects nuclear organization, is evolving as an important parameter indicating cell activation or transformation. In this study, chromatin pattern was evaluated by image analysis of the... -
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- Relationship between Chromatin Pattern of Tumor Cell Nuclei and Transcriptional Sites
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Juhng SW
- KMID: 2172304
- Chonnam Med J.
- 2005 Dec;41(3):253-258.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- The utility of sperm DNA damage assay using toluidine blue and aniline blue staining in routine semen analysis
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Kim HS, Kang MJ, Kim SA, Oh SK, Kim H, Ku SY, Kim SH, Moon SY, Choi YM
- KMID: 1430079
- Clin Exp Reprod Med.
- 2013 Mar;40(1):23-28.
- doi: 10.5653/cerm.2013.40.1.23
OBJECTIVE: The aim of the present study was to examine the relationship among male age, strict morphology, and sperm chromatin structure and condensation. METHODS: Sperm samples from a total of 100... -
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- Influence of Polycomb Proteins and Epigenetic Transcriptional Modifiers on the Development and Activation of T Lymphocytes
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Chun T
- KMID: 2168218
- Hanyang Med Rev.
- 2013 Feb;33(1):33-38.
- doi: 10.7599/hmr.2013.33.1.33
Transcriptional regulation of a gene is not always correlated with genetic information inherited from parents because the transcription of specific genes is often governed by the modification of chromatin structure.... -
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- Sperm nuclear DNA fragmentation and chromatin structure in one-day-old ejaculated sperm
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Jee BC, Suh CS, Shin MS, Lee HJ, Lee JH, Kim SH
- KMID: 2045699
- Clin Exp Reprod Med.
- 2011 Jun;38(2):82-86.
- doi: 10.5653/cerm.2011.38.2.82
OBJECTIVE: To evaluate sperm nuclear DNA fragmentation and chromatin structure after 18 hours'incubation at room temperature. METHODS: Twenty-eight male partners who participating IVF treatment were prospectively included in this study. Ejaculated... -
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- Cytologic Analysis of Microinvasive Squamous Cell Carcinoma of the Uterine Cervix
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Kim EK, Kim YJ, Park JS, Kim HS
- KMID: 2144073
- Korean J Cytopathol.
- 1994 Dec;5(2):99-105.
We studied cervical cytology of 175 cases of histologically confirmed microinvasive squamous cell carcinoma of the uterine cervix in Cheil General Hospital from 1991 to 1993. Excluding 32 cases of... -
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- RNA polymerase II carboxy-terminal domain with multiple connections
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Cho EJ
- KMID: 1047075
- Exp Mol Med.
- 2007 Jun;39(3):247-254.
The largest subunit of eukaryotic RNA polymerase II contains a unique domain at its carboxy-terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of... -
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- The roles of ARID1A in gynecologic cancer
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Mao TL, Shih IM
- KMID: 2177880
- J Gynecol Oncol.
- 2013 Oct;24(4):376-381.
- doi: 10.3802/jgo.2013.24.4.376
One of the exciting findings in recent cancer genome studies is the discovery of somatic mutations in several chromatin remodeling genes. These studies not only illuminate the emerging roles of... -
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