Korean J Gastrointest Endosc.  1995 Sep;15(3):486-493.

A Case of Barrett's Esophageal Ulcer following Esophagomyotomy for Achalasia

Abstract

We report a patient who developed a Barrett,s esophageal ulcer 10 years after esophagomyotomy for achalasia. A-59-year-old female was admitted to the hospital with dysphagia for 2 months. In 1982, she had undergone a modified Heller esophagomyotomy for achalsia. After esophagogram, esophageal manometry, 24hr esophageal pH monitoring, esophagoscophy achalasia and Barrett,s esophageal ulcer was diagnosed. So, she had been treated with omeprazole and sucralfate and has been followed up in a asymtomatic state currently. In Barrett,s esophagus, there is a metaplasia of the normal stratified squamous mucosa to columnar epithelium, caused by the reflux of acid. It appears in approximately 10% of patients with chronic gastroesophageal reflux and is associated with increased probability of adenocarcinoma of the esophagus. Among the predis- posing factors of gastroesophageal reflux, there is treatment of esophageal achalsia by forceful dilatation or by the esophagomyotomy. The resultant ralaxation of lower esophageal sphinter, combined with deficient propulsive esophageal peristalsis, predisposed to gastroesophageal reflux. Actually an increased incidence of gastroesophageal reflux, esophagitis and stricture are well-known complications after esophagomyotomy. But in spite of higher risk of gastroesophageal reflux after esophagomyotomy the development of Barrett,s mucosa has been rarely reported and only recently recognized. Diagnosis of Barrett,s esophagus in such patients is difficult and the cumulative effects of achalasia and Barrett's esophagus predispose these patient to higher risk of developing esophageal carcinoma. So, high index of awareness and regular endoscopic surveillance are required.

Keyword

Barrett's esophagus; Achalasia; Esophagomyotomy

MeSH Terms

Adenocarcinoma
Barrett Esophagus
Constriction, Pathologic
Deglutition Disorders
Diagnosis
Dilatation
Epithelium
Esophageal Achalasia*
Esophageal pH Monitoring
Esophagitis
Esophagus
Female
Gastroesophageal Reflux
Humans
Incidence
Manometry
Metaplasia
Mucous Membrane
Omeprazole
Peristalsis
Sucralfate
Ulcer*
Omeprazole
Sucralfate
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