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A rare complication: Tension pneumothorax after peroral endoscopic myotomy

Kang S, Kim Y, Kim DH

Peroral endoscopic myotomy (POEM) can be safely performed for achalasia. During POEM, gas is insufflated via the endoscope inside the submucosal tunnel. Gas-related complications often cannot be avoided because of...
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Successful Management of Secondary Achalasia in a Patient with Myotonic Dystrophy

Hong JW, Yoon JA, Park HE, Shin YB

Myotonic dystrophy (MD) is a systemic disease that affects any level of the gastrointestinal tract. Due to its rare occurrence, achalasia could be misdiagnosed due to symptoms being similar to...
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The Predictive Value of Intraoperative Esophageal Functional Luminal Imaging Probe Panometry in Patients With Achalasia Undergoing Peroral Endoscopic Myotomy: A Single-center Experience

Hsing LC, Choi K, Jung KW, Joo S, Kim N, Kim GH, Na HK, Ahn JY, Lee J, Kim DH, Choi KD, Song HJ, Lee GH, Jung HY

  • KMID: 2531221
  • J Neurogastroenterol Motil.
  • 2022 Jul;28(3):474-482.
  • doi: 10.5056/jnm21186
Background/Aims We evaluated the clinical significance and prognostic power of functional luminal imaging probe (FLIP) panometry in patients with achalasia treated with peroral endoscopic myotomy (POEM), and examined the clinical parameters...
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Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea

Lee JY, Lim CH, Kim DH, Jung HY, Youn YH, Jung DH, Park JC, Moon HS, Hong SJ, Therapeutic Endoscopy and Instrument for Functional Gastrointestinal Disorders Study Group Under the Korean Society of Neurogastroenterology and Motility

  • KMID: 2528039
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):247-254.
  • doi: 10.5056/jnm21081
Background/Aims To analyze various adverse events (AEs) related to the peroral endoscopic myotomy (POEM) procedure and to analyze whether these AEs are related to an extended hospital stay. Methods Patients admitted for POEM...
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Esophageal Microbiota and Nutritional Intakes in Patients With Achalasia Before and After Peroral Endoscopic Myotomy

Jung DH, Youn YH, Kim DH, Lim CH, Lim HS, Moon HS, Lee JY, Park H, Hong SJ

  • KMID: 2528038
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):237-246.
  • doi: 10.5056/jnm21057
Background/Aims The composition of the microbiota in the esophagus is only partially understood, especially in patients with achalasia. We aim to investigate the esophageal microbial community and nutritional intakes in patients...
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Effect of Drinking Warm Water on Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia

Yoon HJ, Youn YH, Yoo SH, Jeon S, Park H

  • KMID: 2528037
  • J Neurogastroenterol Motil.
  • 2022 Apr;28(2):231-236.
  • doi: 10.5056/jnm21119
Background/Aims Food retention, which is a characteristic observed in patients with achalasia, can interfere with peroral endoscopic myotomy (POEM). However, there is no established guideline for esophageal preparation for POEM. A previous...
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Novel Diagnostic Criteria for Functional Esophageal Disorders

Jung KW

The diagnosis of functional esophageal disorders has evolved from conventional manometry in 1970s to high-resolution manometry in 2010s. The conventional manometry was based on linear plot, whereas newly developed high-resolution...
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Management of pulmonary aspiration due to undiagnosed achalasia during induction of general anesthesia - A case report -

Kim HJ, Choi YS, Jin JH, Lee B

Background: Intraoperative pulmonary aspiration is a rare but potentially fatal complication associated with various risk factors. Preoperative recognition of these risk factors can prevent aspiration events during general anesthesia or...
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Chicago Classification ver. 4.0: Diagnosis of Achalasia and Esophagogastric Junction Outflow Obstruction

Jung KW

Achalasia is a common esophageal motility disorder characterized by inappropriate relaxation of the lower esophageal sphincter and a loss of normal peristalsis in the esophageal body. The newly suggested Chicago...
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Long-term outcomes of surgery for oesophageal achalasia

Ng ZQ, Murphy B, Edmunds S, Whitby M, Tan JH, Archer S

Background: Long-term patient-reported outcomes following surgery for achalasia are lacking in the literature. The aim of this study was to evaluate both short- and long-term outcomes of the surgical management...
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Morphologic Changes in Esophageal Body Movement During Bolus Transport After Peroral Endoscopic Myotomy in Type III Achalasia

Kim AJS, Ong S, Kim JH, Lee HS, Yoon JS, Hur DY

  • KMID: 2523792
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):131-144.
  • doi: 10.5056/jnm21020
Background/Aims The effect of peroral endoscopic myotomy (POEM) on esophageal body movement in achalasia is poorly understood. This study aims to evaluate morphological changes in esophageal body movement after POEM in...
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Role of Peroral Endoscopic Myotomy in Advanced Achalasia Cardia With Sigmoid and/or Megaesophagus: A Systematic Review and Metanalysis

Mandavdhare HS, Kumar M P, Shukla J, Kumar A, Sharma V

  • KMID: 2523780
  • J Neurogastroenterol Motil.
  • 2022 Jan;28(1):15-27.
  • doi: 10.5056/jnm21122
Background/Aims Sigmoid esophagus and/or megaesophagus are considered as an advanced stage in the natural history of achalasia cardia. The role of peroral endoscopic myotomy (POEM) in these subset of patients is...
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Pitfalls in the Interpretation of Chicago Classification for Esophageal Motility Disorders

Herbella FAM, Schlottmann F, Patti MG

  • KMID: 2521150
  • J Neurogastroenterol Motil.
  • 2021 Oct;27(4):513-517.
  • doi: 10.5056/jnm20058
High-resolution manometry permitted the creation of the Chicago classification, that is the categorization for esophageal motility disorders most currently used. Despite its wide acceptance, there are few pitfalls for the...
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The Learning Curve for Peroral Endoscopic Myotomy in Latin America: A Slide to the Right?

Kahaleh M, Tyberg A, Suresh S, Lambroza A, Casas FR, Rey M, Nieto J, Martínez GM, Zamarripa F, Arantes V, Porfilio MG, Gaidhane M, Familiari P, Carames JC, Vargas-Rubio R, Canadas R, Hani A, Munoz G, Castillo B, Moura ET, Galileu FF, Lukashok HP, Robles-Medranda C, Moura EGd

Background/Aims: Per oral endoscopic myotomy (POEM) has been increasingly used for achalasia in Latin America, where Chagas disease is prevalent, and this makes POEM more challenging. The aim of this...
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Histopathological Analysis of Esophageal Mucosa in Patients with Achalasia

Lee BE, Kim GH, Shin N, Park DY, Song GA

Background/Aims: Achalasia is an esophageal motor disorder that leads to functional esophageal obstruction. Food stasis and bacterial fermentation can predispose an individual to esophageal mucosal inflammation, causing multifocal dysplasia and...
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Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia

Vackova Z, Mares J, Krajciova J, Rabekova Z, Zdrhova L, Loudova P, Spicak J, Stirand P, Hucl T, Martinek J

  • KMID: 2514678
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):205-214.
  • doi: 10.5056/jnm20126
Background/Aims Several studies have reported partial recovery of peristalsis in patients with achalasia after myotomy. The aim of our study is to analyze esophageal motility patterns after peroral endoscopic myotomy (POEM)...
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Efficacy and Safety of Peroral Endoscopic Myotomy in Achalasia Patients with Failed Previous Intervention: A Systematic Review and Meta-analysis

Tan S, Zhong C, Ren Y, Luo X, Xu J, Fu X, Peng Y, Tang X

Peroral endoscopic myotomy (POEM) has emerged as a rescue treatment for recurrent or persistent achalasia after failed initial management. Therefore, we aimed to investigate the efficacy and safety of POEM...
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Diagnosis of Dysphagia: High Resolution Manometry & EndoFLIP

Cha B, Jung KW

Esophageal motility disorders were re-defined when high-resolution manometry was employed to better understand their pathogenesis. Newly developed parameters including integrated relaxation pressure (IRP), distal contractile integral, and distal latency showed...
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Novel pre-peroral endoscopic myotomy preparation for esophageal clearance: Simple yet effective!

Desai PN, Patel CN, Kabrawala MV, Mehta RM, Nandwani SK, Prajapati RM, Patel NB, Parekh KK

Background: Having a clean esophagus is an integral part of the peroral endoscopic myotomy (POEM) procedure for ensuring safety and success. Conventional preparation is a tricky, because there is no defined...
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Achalasia During Pregnancy: Proposed Management Algorithm Based on a Thorough Literature Review

Vosko S, Cohen DL, Neeman O, Matalon S, Broide E, Shirin H

  • KMID: 2510058
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):8-18.
  • doi: 10.5056/jnm20181
Fewer than 40 cases of achalasia occurring in pregnant woman have been reported in the literature. Given the rarity of achalasia during pregnancy, and the numerous treatment options that are...
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