Korean J Med.  2015 Mar;88(3):340-345. 10.3904/kjm.2015.88.3.340.

A Case of Acute Osteomyelitis of the Femur Caused by Nalidixic-Acid-Resistant Salmonella enteritidis

• Na SK
• Kim TJ
• Lee JA
• Lee SS
• Koh SH
• Kim TY
• Kim HS

• KMID: 2082598
• DOI: http://doi.org/10.3904/kjm.2015.88.3.340

Abstract

Infection with nontyphoidal Salmonella most often results in self-limited acute gastroenteritis. However, occasionally it causes bacteremia and localized infection requiring antibiotic treatment. A third-generation cephalosporin or fluoroquinolone is often the first choice of antibiotic. However, there has been an increase in nalidixic-acid-resistant nontyphoidal Salmonella with decreased fluoroquinolone susceptibility. Although there have been many cases reported of nontyphoidal Salmonella, no cases of nalidixic-acid-resistant nontyphoidal Salmonella have been reported in Korea. Here, we report on the case of a 61-year-old man with a diagnosis of acute osteomyelitis and periosteal abscess of the femur caused by nalidixic-acid-resistant Salmonella enteritidis. He was treated successfully with prolonged administration of a high-dose of ciprofloxacin and drainage of the abscess.

Keyword

Salmonella enteritidis; Osteomyelitis; Nalidixic acid; Drug resistance

MeSH Terms

Abscess
Bacteremia
Ciprofloxacin
Diagnosis
Drainage
Drug Resistance
Femur*
Gastroenteritis
Humans
Korea
Middle Aged
Nalidixic Acid
Osteomyelitis*
Salmonella
Salmonella enteritidis*
Ciprofloxacin
Nalidixic Acid