Korean J Nephrol.  2003 Nov;22(6):753-756.

Severe Acute Renal Failure Requiring Hemodialysis Treatment due to Malignant Hyperthermia

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. cmckyo@yahoo.co.kr
  • 2Department of Plastic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 3Department of Anesthesiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Malignant hyperthermia is an inherited hypermetabolic syndrome, characterized by temperature elevation, muscle destruction, muscle rigidity, high oxygen consumption, and metabolic acidosis. It is usually triggered by anesthetic agents and neuromuscular relaxants. We present a case of malignant hyperthermia who developed rhabdomyolysis, acute renal failure, disseminated intravascular coagulopathy following an apparently uneventful general anesthesia. Anesthesia was induced with thiopental sodium and succinylcholine. He was successfully treated with dantrolene along with cardiopulmonary resuscitation and hemodialysis.

Keyword

Malignant hyperthermia; Anesthesia; Acute renal failure; Rhabdomyolysis; Hemodialysis

MeSH Terms

Acidosis
Acute Kidney Injury*
Anesthesia
Anesthesia, General
Anesthetics
Cardiopulmonary Resuscitation
Dantrolene
Malignant Hyperthermia*
Muscle Rigidity
Oxygen Consumption
Renal Dialysis*
Rhabdomyolysis
Succinylcholine
Thiopental
Anesthetics
Dantrolene
Succinylcholine
Thiopental
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