Korean J Otorhinolaryngol-Head Neck Surg.
2011 Aug;54(8):509-518. 10.3342/kjorl-hns.2011.54.8.509.
Endolymphatic Hydrops: Pathophysiology and Etiology
- Affiliations
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- 1Department of Otolaryngology, School of Medicine, Keimyung University, Daegu, Korea. entnamsi@dsmc.or.kr
- KMID: 2074178
- DOI: http://doi.org/10.3342/kjorl-hns.2011.54.8.509
Abstract
- Endolymphatic hydrops (EH) represents a histopathologic finding in which the structures bounding the endolymphatic space are distended by an enlargement of endolymphatic volume. EH primarily involves the cochlear duct and saccule but can involve the utricle and ampullae of the semicircular canals. EH is a consistent finding in patients with Meniere's disease, however, the reverse is not true. EH may occur as a consequence of a variety of disorders, including DFNA 9, Alport syndrome, serous labyrinthitis, suppurative labyrinthitis, otosyphilis, temporal bone fracture, surgical trauma, neoplasm, immune disorders, otosclerosis, or Paget's disease. The mechanism of development of hydrops is also unclear. This review provides information to understand the recent pathophysiologic mechanism and causal disoders in EH.
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