J Korean Neurosurg Soc.  2001 Jun;30(6):786-789.

Alveolar Soft Part Sarcoma Metastatic to the Brain

• Cheong JH
• Kim CH
• Bak KH
• Kim JM
• Oh SJ

Abstract

Alveolar Soft Part Sarcoma(ASPS) is a rare entity that invariably ends in death from the disseminated disease. Although the most common site of metastasis is the lung, the central nervous system is also the third common site. Its histogenesis remains to be unknown and the gold standard treatment is radically surgical removal of the mass. However, adjuvant chemotherapy and radiotherapy are known to be less effective. The authors present a 24-year-old man who was admitted with headache and neck discomfort. Magnetic resonance(MR) imaging scans demonstrated multiple masses in the left frontal lobe, parietal lobe, and right cerebellum. The patient underwent surgery to remove multiple masses in the staged fashion. The postoperative course was uneventful, but the patient committed suicide 5 months later. The authors reviewed the pertinent literature and discussed this clinical entity with references.

Keyword

Alveolar Soft Part Sarcoma; Metastasis; Brain; Radical removal

MeSH Terms

Brain*
Central Nervous System
Cerebellum
Chemotherapy, Adjuvant
Frontal Lobe
Headache
Humans
Lung
Neck
Neoplasm Metastasis
Parietal Lobe
Radiotherapy
Sarcoma, Alveolar Soft Part*
Suicide
Young Adult