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Association between Lymphovascular Invasion and Recurrence in Patients with pT1N+ or pT2–3N0 Gastric Cancer: a Multi-institutional Dataset Analysis

Fujita K, Kanda M, Ito S, Mochizuki , Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi , Fujiwara M, Murotani K, Kodera Y

PURPOSE: Patients with pathological stage T1N+ or T2–3N0 gastric cancer may experience disease recurrence following curative gastrectomy. However, the current Japanese Gastric Cancer Treatment Guidelines do not recommend postoperative adjuvant...
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Germline PALB2, ATM variants in a patient with breast and ovarian cancer at risk for familial cancer syndrome: Is there a role for risk-reducing salpingo-oophorectomy?

Carbajal-Mamani SL, Markham MJ, Santolaya-Forgas J, Castagno J, Cardenas-Goicoechea J

A 50-year-old non-Hispanic white Caucasian female was diagnosed with breast cancer and was subsequently found to possess the tumorigenic ataxia telangiectasia mutated (ATM) and PALB2 variants but not the BRCA1...
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Living donor liver transplantation with total pancreatectomy and portal vein homograft replacement in a pediatric patient with advanced pancreatoblastoma

Namgoong J, Hwang S, Oh SH, Kim KM, Park GC, Ahn CS, Kwon H, Cho YJ, Kwon YJ

Pancreatoblastoma is a malignant exocrine pancreatic tumor that is usually present in childhood. We herein present one case of pediatric living donor liver transplantation (LDLT) combined with spleen-preserving regional total...
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Living-donor liver transplantation with inferior vena cava replacement in an infant recipient with advanced hepatoblastoma

Namgoong J, Hwang S, Oh SH, Kim KM, Park GC, Ahn CS, Kwon H, Cho YJ, Kwon YJ

Replacement of the inferior vena cava (IVC) after concurrent resection of hepatoblastoma-containing liver and retrohepatic IVC is regarded as a feasible option for pediatric living-donor liver transplantation (LDLT). This technique...
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Adult Ileocolic Intussusception Caused by Diffuse Large B Cell Lymphoma

Park JW, Song GA, Baek DH, Kim GH, Lee BE, Lee MW, Han SY, Park YJ, Park EY

Intussusception is a medical condition, in which a proximal part of the intestine folds into the distal intestine. Adult intussusceptions are rare and account for approximately 5% of all cases...
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Omission of Chemotherapy for the Treatment of Mucinous Breast Cancer: A Nationwide Study from the Korean Breast Cancer Society

Kim HS, Lee JU, Yoo TK, Chae BJ, Son D, Kim YJ, Park WC

PURPOSE: Mucinous breast carcinoma (MBC) is a rare type of breast cancer. Although patients with MBC may have a better prognosis than that of patients with invasive ductal carcinoma, many...
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Comparison of the Beneficial Effects of Adjuvant Chemotherapy among Young and Old Aged Breast Cancer Patients

Mok S, Yoo TK, Chae BJ

PURPOSE: Breast cancer rates are expected to rise with an increasingly aging society. However, research on breast cancer among elderly women is scarce. In the present study, we aimed to...
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Two Cases of Unresectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgical Resection

Huh G, Chun JW, You MS, Paik WH, Lee SH, Kim YT, Ryu JK

We report two cases of patients with unresectable pancreatic cancer treated with neoadjuvant chemotherapy and surgical resection. In the first case, main mass was located at the neck of the...
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Impact of Adjuvant Chemotherapy Completion on Oncologic Outcomes in ypTNMstage 2 Rectal Cancer Patients

Park YY, Lee KY, Kim NK, Lee SB, Kim GR, Min BS, Oh ST

PURPOSE: Adjuvant chemotherapy (aCT) in rectal cancer patients who have undergone curative resection after neoadjuvant chemoradiation (nCRT) is controversial. We aimed to investigate the benefits of using aCT and the...
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Anemic Retinopathy after Chemotherapy

Lee SC, Oh BL

PURPOSE: To report a case of anemic retinopathy after chemotherapy. CASE SUMMARY: A 32-year-old male presented with visual disturbance in both eyes. He had been diagnosed with testicular cancer and had...
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Risk Factors for Gallbladder Stone Formation after Gastric Cancer Surgery

Lee YW, Kim A, Han M, Yoo MW

PURPOSE: Although an increased incidence of gallbladder (GB) stone formation after gastrectomy has been reported, its etiology remains uncertain. The goal of this study was to explore the incidence of...
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A phase II study of neoadjuvant chemotherapy plus durvalumab and tremelimumab in advanced-stage ovarian cancer: a Korean Gynecologic Oncology Group Study (KGOG 3046), TRU-D

Lee JY, Kim JW, Lim MC, Kim S, Kim HS, Choi CH, Yi JY, Park SY, Kim BG, on behalf of KGOG investigators

BACKGROUND: A single-arm phase II study of neoadjuvant chemotherapy plus durvalumab and tremelimumab in the treatment of advanced-stage ovarian cancer has begun in Korea. We hypothesized that adding durvalumab (anti-programmed...
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Evaluation of non-completion of intraperitoneal chemotherapy in patients with advanced epithelial ovarian cancer

Chambers L, Son J, Radeva M, DeBernardo R

OBJECTIVE: To identify factors associated with non-completion of intraperitoneal with intravenous chemotherapy [IP/IV] in women with epithelial ovarian cancer (EOC). METHODS: This was an Institutional Review Board approved, retrospective cohort study...
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Indication for and Effect of Adjuvant Chemotherapy for Stage IIa (T3N0M0) Colon Cancer

Jeon CH, Kim MK, Lee IK

PURPOSE: The efficacy of adjuvant chemotherapy (AC) in stage IIa colon cancer is controversial. This study aimed to investigate the factors influencing survival in patients with stage IIa colon cancer,...
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Loss of LKB1 Protein Expression Correlates with Increased Risk of Recurrence and Death in Patients with Resected, Stage II or III Colon Cancer

Sfakianaki M, Papadaki C, Tzardi M, Trypaki M, Alam S, Lagoudaki , Messaritakis I, Zoras O, Mavroudis , Georgoulias V, Souglakos

PURPOSE: The purpose of this study was to investigate the prognostic significance of liver kinase b1 (LKB1) loss in patients with operable colon cancer (CC). MATERIALS AND METHODS: Two hundred sixty-two...
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Impact of 21-Gene Recurrence Score on Chemotherapy Decision in Invasive Ductal Carcinoma of Breast with Nodal Micrometastases

Chen WR, Deng JP, Wang J, Sun JY, He ZY, Wu SG

PURPOSE: The purpose of this study was to investigate the effect of 21-gene recurrence score (RS) on predicting prognosis and chemotherapy decision in node micrometastases (N1mi) breast invasive ductal carcinoma...
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Clinicopathological Characterization and Prognostic Implication of SMAD4 Expression in Colorectal Carcinoma

Yoo SY, Lee JA, Shin Y, Cho NY, Bae JM, Kang GH

BACKGROUND: SMAD family member 4 (SMAD4) has gained attention as a promising prognostic factor of colorectal cancer (CRC) as well as a key molecule to understand the tumorigenesis and progression...
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Changes of Cognitive Function and Fatigue following Chemotherapy in Patients with Gastrointestinal Cancer: A Prospective Controlled Study

Oh PJ, Moon SM

PURPOSE: This study was to identify changes in cognitive function and fatigue following chemotherapy in patients with stomach or colorectal cancer. METHODS: Of the participants, 67 underwent adjuvant chemotherapy, while 66...
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Clinical Implementation of Precision Medicine in Gastric Cancer

Jeon J, Cheong JH

Gastric cancer (GC) is one of the deadliest malignancies in the world. Currently, clinical treatment decisions are mostly made based on the extent of the tumor and its anatomy, such...
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Lymph-vascular space invasion (LVSI) as a strong and independent predictor for non-locoregional recurrences in endometrial cancer: a Danish Gynecological Cancer Group Study

Ørtoft G, Lausten-Thomsen L, Høgdall C, Hansen ES, Dueholm M

OBJECTIVE: To evaluate the effect of lymph-vascular space invasion (LVSI) on location of recurrences in Danish patients with endometrial cancer. METHODS: This national cohort study (2005–2012) included 4,380 radically operated patients...
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